Guido de La Torre Olvera, Miroslav Hnatko, Magdaléna Precnerová, Ivo Dlouhý, Monika Tatarková
{"title":"生物医学应用氮化硅-羟基磷灰石复合支架的定制力学性能","authors":"Guido de La Torre Olvera, Miroslav Hnatko, Magdaléna Precnerová, Ivo Dlouhý, Monika Tatarková","doi":"10.1111/ijac.70007","DOIUrl":null,"url":null,"abstract":"<p>Silicon nitride (Si<sub>3</sub>N<sub>4</sub>)–hydroxyapatite (HA) composite scaffolds for bone replacement were developed via pressure infiltration of HA into a porous Si<sub>3</sub>N<sub>4</sub> matrix. The effect of replication processing parameters (SiO<sub>2</sub> content, number of infiltrations, and calcination temperature) on the structure and mechanical properties of the porous Si<sub>3</sub>N<sub>4</sub> matrix was investigated and compared to human trabecular bone. All fabricated Si<sub>3</sub>N<sub>4</sub> matrices exhibited interconnected porosity comparable to trabecular bone. A matrix processed with double infiltration with 15 wt.% SiO<sub>2</sub> suspension, followed by calcination at 1100°C, demonstrated the highest compressive strength. Subsequent pressure infiltration with HA significantly enhanced both the compressive (∼ twofold) and tensile strength (> quadruple) of this matrix, yielding a composite scaffold with a compressive strength similar to that of human trabecular bone, while maintaining comparable microporosity.</p>","PeriodicalId":13903,"journal":{"name":"International Journal of Applied Ceramic Technology","volume":"22 5","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tailored mechanical properties of silicon nitride–hydroxyapatite composite scaffolds for biomedical applications\",\"authors\":\"Guido de La Torre Olvera, Miroslav Hnatko, Magdaléna Precnerová, Ivo Dlouhý, Monika Tatarková\",\"doi\":\"10.1111/ijac.70007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Silicon nitride (Si<sub>3</sub>N<sub>4</sub>)–hydroxyapatite (HA) composite scaffolds for bone replacement were developed via pressure infiltration of HA into a porous Si<sub>3</sub>N<sub>4</sub> matrix. The effect of replication processing parameters (SiO<sub>2</sub> content, number of infiltrations, and calcination temperature) on the structure and mechanical properties of the porous Si<sub>3</sub>N<sub>4</sub> matrix was investigated and compared to human trabecular bone. All fabricated Si<sub>3</sub>N<sub>4</sub> matrices exhibited interconnected porosity comparable to trabecular bone. A matrix processed with double infiltration with 15 wt.% SiO<sub>2</sub> suspension, followed by calcination at 1100°C, demonstrated the highest compressive strength. Subsequent pressure infiltration with HA significantly enhanced both the compressive (∼ twofold) and tensile strength (> quadruple) of this matrix, yielding a composite scaffold with a compressive strength similar to that of human trabecular bone, while maintaining comparable microporosity.</p>\",\"PeriodicalId\":13903,\"journal\":{\"name\":\"International Journal of Applied Ceramic Technology\",\"volume\":\"22 5\",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-06-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Applied Ceramic Technology\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://ceramics.onlinelibrary.wiley.com/doi/10.1111/ijac.70007\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, CERAMICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Applied Ceramic Technology","FirstCategoryId":"88","ListUrlMain":"https://ceramics.onlinelibrary.wiley.com/doi/10.1111/ijac.70007","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, CERAMICS","Score":null,"Total":0}
Tailored mechanical properties of silicon nitride–hydroxyapatite composite scaffolds for biomedical applications
Silicon nitride (Si3N4)–hydroxyapatite (HA) composite scaffolds for bone replacement were developed via pressure infiltration of HA into a porous Si3N4 matrix. The effect of replication processing parameters (SiO2 content, number of infiltrations, and calcination temperature) on the structure and mechanical properties of the porous Si3N4 matrix was investigated and compared to human trabecular bone. All fabricated Si3N4 matrices exhibited interconnected porosity comparable to trabecular bone. A matrix processed with double infiltration with 15 wt.% SiO2 suspension, followed by calcination at 1100°C, demonstrated the highest compressive strength. Subsequent pressure infiltration with HA significantly enhanced both the compressive (∼ twofold) and tensile strength (> quadruple) of this matrix, yielding a composite scaffold with a compressive strength similar to that of human trabecular bone, while maintaining comparable microporosity.
期刊介绍：
The International Journal of Applied Ceramic Technology publishes cutting edge applied research and development work focused on commercialization of engineered ceramics, products and processes. The publication also explores the barriers to commercialization, design and testing, environmental health issues, international standardization activities, databases, and cost models. Designed to get high quality information to end-users quickly, the peer process is led by an editorial board of experts from industry, government, and universities. Each issue focuses on a high-interest, high-impact topic plus includes a range of papers detailing applications of ceramics. Papers on all aspects of applied ceramics are welcome including those in the following areas:
Nanotechnology applications;
Ceramic Armor;
Ceramic and Technology for Energy Applications (e.g., Fuel Cells, Batteries, Solar, Thermoelectric, and HT Superconductors);
Ceramic Matrix Composites;
Functional Materials;
Thermal and Environmental Barrier Coatings;
Bioceramic Applications;
Green Manufacturing;
Ceramic Processing;
Glass Technology;
Fiber optics;
Ceramics in Environmental Applications;
Ceramics in Electronic, Photonic and Magnetic Applications;
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
