T. V. Shein, E. A. Berendeev, V. S. Degtyarev, A. M. Koshkarev, A. S. Kuznetsov, S. S. Savinov, S. Yu. Taskaev
{"title":"基于VITA加速器的中子源束整形组件","authors":"T. V. Shein, E. A. Berendeev, V. S. Degtyarev, A. M. Koshkarev, A. S. Kuznetsov, S. S. Savinov, S. Yu. Taskaev","doi":"10.1134/S1547477125700700","DOIUrl":null,"url":null,"abstract":"<p>The VITA accelerator-based neutron source has been proposed and developed at the Budker Institute of Nuclear Physics (Novosibirsk, Russia) for boron neutron capture therapy (BNCT), which includes a vacuum-insulated tandem accelerator for proton beam production, a lithium target for neutron generation through the <sup>7</sup>Li(<i>p</i>, <i>n</i>)<sup>7</sup>Be reaction, and a neutron beam shaping assembly (BSA) with MgF<sub>2</sub> moderator for therapeutic beam generation. This paper presents a comparison of the results of numerical simulations of boron dose and γ-ray dose spatial distributions in a water phantom for three different neutron beam shaping assemblies. The investigations are carried out at the VITA accelerator-based neutron source in the Budker Institute of Nuclear Physics, Siberian branch, Russian Academy of Sciences, using a small neutron detector to measure these components of ionizing radiation. An agreement between the measured and simulated results is obtained. For the VITA accelerator neutron source that was manufactured and is being supplied to the Blokhin National Medical Research Center of Oncology in Moscow with the purpose of conducting clinical trials of the BNCT technique in Russia and the subsequent treatment of patients, the BSA is optimized by numerical simulation with consideration for the equipment, the presence of structural materials, and the wall separating the installation room from the irradiation room. The description of materials that make it possible to form a neutron beam that meets the requirements of the BNCT and the design of manufactured BSA is presented.</p>","PeriodicalId":730,"journal":{"name":"Physics of Particles and Nuclei Letters","volume":"22 4","pages":"842 - 846"},"PeriodicalIF":0.4000,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Beam Shaping Assembly of the VITA Accelerator-Based Neutron Source\",\"authors\":\"T. V. Shein, E. A. Berendeev, V. S. Degtyarev, A. M. Koshkarev, A. S. Kuznetsov, S. S. Savinov, S. Yu. Taskaev\",\"doi\":\"10.1134/S1547477125700700\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The VITA accelerator-based neutron source has been proposed and developed at the Budker Institute of Nuclear Physics (Novosibirsk, Russia) for boron neutron capture therapy (BNCT), which includes a vacuum-insulated tandem accelerator for proton beam production, a lithium target for neutron generation through the <sup>7</sup>Li(<i>p</i>, <i>n</i>)<sup>7</sup>Be reaction, and a neutron beam shaping assembly (BSA) with MgF<sub>2</sub> moderator for therapeutic beam generation. This paper presents a comparison of the results of numerical simulations of boron dose and γ-ray dose spatial distributions in a water phantom for three different neutron beam shaping assemblies. The investigations are carried out at the VITA accelerator-based neutron source in the Budker Institute of Nuclear Physics, Siberian branch, Russian Academy of Sciences, using a small neutron detector to measure these components of ionizing radiation. An agreement between the measured and simulated results is obtained. For the VITA accelerator neutron source that was manufactured and is being supplied to the Blokhin National Medical Research Center of Oncology in Moscow with the purpose of conducting clinical trials of the BNCT technique in Russia and the subsequent treatment of patients, the BSA is optimized by numerical simulation with consideration for the equipment, the presence of structural materials, and the wall separating the installation room from the irradiation room. The description of materials that make it possible to form a neutron beam that meets the requirements of the BNCT and the design of manufactured BSA is presented.</p>\",\"PeriodicalId\":730,\"journal\":{\"name\":\"Physics of Particles and Nuclei Letters\",\"volume\":\"22 4\",\"pages\":\"842 - 846\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-08-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physics of Particles and Nuclei Letters\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1547477125700700\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHYSICS, PARTICLES & FIELDS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics of Particles and Nuclei Letters","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S1547477125700700","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, PARTICLES & FIELDS","Score":null,"Total":0}
Beam Shaping Assembly of the VITA Accelerator-Based Neutron Source
The VITA accelerator-based neutron source has been proposed and developed at the Budker Institute of Nuclear Physics (Novosibirsk, Russia) for boron neutron capture therapy (BNCT), which includes a vacuum-insulated tandem accelerator for proton beam production, a lithium target for neutron generation through the 7Li(p, n)7Be reaction, and a neutron beam shaping assembly (BSA) with MgF2 moderator for therapeutic beam generation. This paper presents a comparison of the results of numerical simulations of boron dose and γ-ray dose spatial distributions in a water phantom for three different neutron beam shaping assemblies. The investigations are carried out at the VITA accelerator-based neutron source in the Budker Institute of Nuclear Physics, Siberian branch, Russian Academy of Sciences, using a small neutron detector to measure these components of ionizing radiation. An agreement between the measured and simulated results is obtained. For the VITA accelerator neutron source that was manufactured and is being supplied to the Blokhin National Medical Research Center of Oncology in Moscow with the purpose of conducting clinical trials of the BNCT technique in Russia and the subsequent treatment of patients, the BSA is optimized by numerical simulation with consideration for the equipment, the presence of structural materials, and the wall separating the installation room from the irradiation room. The description of materials that make it possible to form a neutron beam that meets the requirements of the BNCT and the design of manufactured BSA is presented.
期刊介绍:
The journal Physics of Particles and Nuclei Letters, brief name Particles and Nuclei Letters, publishes the articles with results of the original theoretical, experimental, scientific-technical, methodological and applied research. Subject matter of articles covers: theoretical physics, elementary particle physics, relativistic nuclear physics, nuclear physics and related problems in other branches of physics, neutron physics, condensed matter physics, physics and engineering at low temperatures, physics and engineering of accelerators, physical experimental instruments and methods, physical computation experiments, applied research in these branches of physics and radiology, ecology and nuclear medicine.