{"title":"在埃塞俄比亚亚的斯亚贝巴Ras Desta Damtew纪念医院随访的糖尿病患者外周血管疾病及其相关因素","authors":"Zerihun Chala Deme , Getchew Fekadu Feda , Dereje Tsegaye , Agumasie Semahegn","doi":"10.1016/j.endmts.2025.100271","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to assess the prevalence of peripheral vascular disorders and associated factors among diabetic patients on follow-up at Ras Desta Damtew Memorial Hospital, Ethiopia.</div></div><div><h3>Methods</h3><div>An institutional-based cross-sectional study was conducted among 275 randomly selected Diabetes Mellitus patients attending follow-up at Ras Desta Damtew Memorial Hospital, Addis Ababa, Ethiopia, from July to August 2024. Data were collected using structured questionnaires, ankle-brachial index, and Edinburgh Claudication Questionnaire, IPAQ-SF. Data were entered into Epi-data version 4.6 and exported to SPSS version 25 for analysis. Bi-variable and multivariable binary logistic regression analyses were conducted to determine associations between dependent and independent variables. Adjusted odds ratios with 95 % confidence intervals were reported, and statistical significance was considered at <em>p</em> ≤ 0.05.</div></div><div><h3>Results</h3><div>The study found that 12 % (95 % CI: 8.15 %–15.85 %) of diabetic patients developed peripheral vascular disorders. Significant associations were found with smoking (AOR: 5.59; 3.42–8.63), alcohol use (AOR: 4.09; 2.56–7.74), hypertension (AOR: 3.55; 1.69–6.25), and physical inactivity (AOR: 3.80; 1.56–9.47).</div></div><div><h3>Conclusions</h3><div>Over one in ten diabetic patients developed peripheral vascular disease. Key associated factors include smoking, alcohol use, hypertension, and physical inactivity. Interventions targeting these risk factors are necessary to reduce related complications in diabetic patients.</div></div>","PeriodicalId":34427,"journal":{"name":"Endocrine and Metabolic Science","volume":"19 ","pages":"Article 100271"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Peripheral vascular disease and its associated factors among diabetic patients on follow-up at Ras Desta Damtew Memorial Hospital, Addis Ababa, Ethiopia\",\"authors\":\"Zerihun Chala Deme , Getchew Fekadu Feda , Dereje Tsegaye , Agumasie Semahegn\",\"doi\":\"10.1016/j.endmts.2025.100271\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>This study aimed to assess the prevalence of peripheral vascular disorders and associated factors among diabetic patients on follow-up at Ras Desta Damtew Memorial Hospital, Ethiopia.</div></div><div><h3>Methods</h3><div>An institutional-based cross-sectional study was conducted among 275 randomly selected Diabetes Mellitus patients attending follow-up at Ras Desta Damtew Memorial Hospital, Addis Ababa, Ethiopia, from July to August 2024. Data were collected using structured questionnaires, ankle-brachial index, and Edinburgh Claudication Questionnaire, IPAQ-SF. Data were entered into Epi-data version 4.6 and exported to SPSS version 25 for analysis. Bi-variable and multivariable binary logistic regression analyses were conducted to determine associations between dependent and independent variables. Adjusted odds ratios with 95 % confidence intervals were reported, and statistical significance was considered at <em>p</em> ≤ 0.05.</div></div><div><h3>Results</h3><div>The study found that 12 % (95 % CI: 8.15 %–15.85 %) of diabetic patients developed peripheral vascular disorders. Significant associations were found with smoking (AOR: 5.59; 3.42–8.63), alcohol use (AOR: 4.09; 2.56–7.74), hypertension (AOR: 3.55; 1.69–6.25), and physical inactivity (AOR: 3.80; 1.56–9.47).</div></div><div><h3>Conclusions</h3><div>Over one in ten diabetic patients developed peripheral vascular disease. Key associated factors include smoking, alcohol use, hypertension, and physical inactivity. Interventions targeting these risk factors are necessary to reduce related complications in diabetic patients.</div></div>\",\"PeriodicalId\":34427,\"journal\":{\"name\":\"Endocrine and Metabolic Science\",\"volume\":\"19 \",\"pages\":\"Article 100271\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Endocrine and Metabolic Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666396125000573\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endocrine and Metabolic Science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666396125000573","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目的本研究旨在评估在埃塞俄比亚Ras Desta Damtew纪念医院随访的糖尿病患者外周血管疾病的患病率及相关因素。方法对2024年7月至8月在埃塞俄比亚亚的斯亚贝巴Ras Desta Damtew纪念医院随访的275例糖尿病患者进行了一项基于机构的横断面研究。采用结构化问卷、踝臂指数和爱丁堡跛行问卷(IPAQ-SF)收集数据。数据输入Epi-data 4.6版本,导出到SPSS 25版本进行分析。进行双变量和多变量二元逻辑回归分析,以确定因变量和自变量之间的关联。校正优势比为95%置信区间,p≤0.05认为有统计学意义。结果研究发现,12% (95% CI: 8.15% - 15.85%)的糖尿病患者发生周围血管病变。与吸烟有显著相关性(AOR: 5.59;3.42-8.63),酒精使用(AOR: 4.09;2.56-7.74),高血压(AOR: 3.55;1.69-6.25),缺乏身体活动(AOR: 3.80;1.56 - -9.47)。结论1 / 10以上的糖尿病患者发生周围血管病变。主要的相关因素包括吸烟、饮酒、高血压和缺乏身体活动。针对这些危险因素的干预措施对于减少糖尿病患者的相关并发症是必要的。
Peripheral vascular disease and its associated factors among diabetic patients on follow-up at Ras Desta Damtew Memorial Hospital, Addis Ababa, Ethiopia
Objective
This study aimed to assess the prevalence of peripheral vascular disorders and associated factors among diabetic patients on follow-up at Ras Desta Damtew Memorial Hospital, Ethiopia.
Methods
An institutional-based cross-sectional study was conducted among 275 randomly selected Diabetes Mellitus patients attending follow-up at Ras Desta Damtew Memorial Hospital, Addis Ababa, Ethiopia, from July to August 2024. Data were collected using structured questionnaires, ankle-brachial index, and Edinburgh Claudication Questionnaire, IPAQ-SF. Data were entered into Epi-data version 4.6 and exported to SPSS version 25 for analysis. Bi-variable and multivariable binary logistic regression analyses were conducted to determine associations between dependent and independent variables. Adjusted odds ratios with 95 % confidence intervals were reported, and statistical significance was considered at p ≤ 0.05.
Results
The study found that 12 % (95 % CI: 8.15 %–15.85 %) of diabetic patients developed peripheral vascular disorders. Significant associations were found with smoking (AOR: 5.59; 3.42–8.63), alcohol use (AOR: 4.09; 2.56–7.74), hypertension (AOR: 3.55; 1.69–6.25), and physical inactivity (AOR: 3.80; 1.56–9.47).
Conclusions
Over one in ten diabetic patients developed peripheral vascular disease. Key associated factors include smoking, alcohol use, hypertension, and physical inactivity. Interventions targeting these risk factors are necessary to reduce related complications in diabetic patients.