将聚合物分形微网集成到超形态心电图监测中的仿生气泡门控策略。

IF 16 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY
ACS Nano Pub Date : 2025-08-10 DOI:10.1021/acsnano.5c05701
Ke He, Kui Wang, Yuchen Yue, Shiqi Cao, Hanfei Gao*, Bo Zhang, Wei Li, Huixue Su, Ye Zhang, Wei Li, Jiangang Feng, Junchuan Yang*, Xuesong Zhang*, Lei Jiang and Yuchen Wu, 
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引用次数: 0

摘要

具有几何工程的超柔性聚合物电子器件由于其应变耐受性、高载流子迁移率和生物相容性,在适形植入医疗设备中具有很高的应用前景。然而,由于聚合物链的分子纠缠和不可控的毛细管流动,通过溶液工艺制造高分辨率、连续和均匀的聚合物图案仍然是一个重大挑战,从而限制了其设备的性能和可扩展性。在此,我们引入了一种生物启发的气泡门控策略来定向引导毛细管流动,以制造基于半导体聚合物的分形微网。受木质部分层液体输送的启发,我们开发了一种气泡门控微流控系统来调节液体分布,促进大面积、均匀的聚合物分形微网的远程有序组装。基于这些微网格,我们制备了在x和y方向同时150%应变下性能稳定的超柔性oect。此外,我们在兔子心脏上设计了一个高度超常规的心电图(ECG)检测器,提供准确的ECG信号监测。该策略不仅克服了关键的制造挑战,而且在推进植入式设备和生物传感器的应用方面具有重要的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Bioinspired Bubble-Gated Strategy for Integrating a Polymer Fractal Micromesh toward Ultraconformal Electrocardiogram Monitoring

Bioinspired Bubble-Gated Strategy for Integrating a Polymer Fractal Micromesh toward Ultraconformal Electrocardiogram Monitoring

Ultraflexible polymer electronic devices with geometry engineering are highly promising for applications in conformal implantable medical devices owing to their strain tolerance, high charge carrier mobility, and biocompatibility. However, due to molecular entanglement of polymer chains and uncontrollable capillary flows, it remains a significant challenge to fabricate high-resolution, continuous, and uniform polymer patterns via solution processes, thus limiting the performance and scalability of their devices. Herein, we introduced a bioinspired bubble-gated strategy to directionally guide capillary flows for the fabrication of fractal micromeshes based on semiconductive polymers. Inspired by hierarchical liquid transport in the tree xylem, we developed a bubble-gated microfluidic system to regulate liquid distribution, facilitating the confined assembly of large-area, uniform polymer fractal micromeshes with a long-range order. Based on these micromeshes, we fabricated ultraflexible OECTs with stable performances under simultaneous 150% strain in both the x- and y-directions. Furthermore, we engineered a highly ultraconformal electrocardiogram (ECG) detector onto a rabbit heart, providing accurate ECG signal monitoring. This strategy not only overcomes key fabrication challenges but also holds significant promise for advancing applications in implantable devices and biosensors.

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来源期刊
ACS Nano
ACS Nano 工程技术-材料科学:综合
CiteScore
26.00
自引率
4.10%
发文量
1627
审稿时长
1.7 months
期刊介绍: ACS Nano, published monthly, serves as an international forum for comprehensive articles on nanoscience and nanotechnology research at the intersections of chemistry, biology, materials science, physics, and engineering. The journal fosters communication among scientists in these communities, facilitating collaboration, new research opportunities, and advancements through discoveries. ACS Nano covers synthesis, assembly, characterization, theory, and simulation of nanostructures, nanobiotechnology, nanofabrication, methods and tools for nanoscience and nanotechnology, and self- and directed-assembly. Alongside original research articles, it offers thorough reviews, perspectives on cutting-edge research, and discussions envisioning the future of nanoscience and nanotechnology.
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