Ke He, Kui Wang, Yuchen Yue, Shiqi Cao, Hanfei Gao*, Bo Zhang, Wei Li, Huixue Su, Ye Zhang, Wei Li, Jiangang Feng, Junchuan Yang*, Xuesong Zhang*, Lei Jiang and Yuchen Wu,
{"title":"将聚合物分形微网集成到超形态心电图监测中的仿生气泡门控策略。","authors":"Ke He, Kui Wang, Yuchen Yue, Shiqi Cao, Hanfei Gao*, Bo Zhang, Wei Li, Huixue Su, Ye Zhang, Wei Li, Jiangang Feng, Junchuan Yang*, Xuesong Zhang*, Lei Jiang and Yuchen Wu, ","doi":"10.1021/acsnano.5c05701","DOIUrl":null,"url":null,"abstract":"<p >Ultraflexible polymer electronic devices with geometry engineering are highly promising for applications in conformal implantable medical devices owing to their strain tolerance, high charge carrier mobility, and biocompatibility. However, due to molecular entanglement of polymer chains and uncontrollable capillary flows, it remains a significant challenge to fabricate high-resolution, continuous, and uniform polymer patterns via solution processes, thus limiting the performance and scalability of their devices. Herein, we introduced a bioinspired bubble-gated strategy to directionally guide capillary flows for the fabrication of fractal micromeshes based on semiconductive polymers. Inspired by hierarchical liquid transport in the tree xylem, we developed a bubble-gated microfluidic system to regulate liquid distribution, facilitating the confined assembly of large-area, uniform polymer fractal micromeshes with a long-range order. Based on these micromeshes, we fabricated ultraflexible OECTs with stable performances under simultaneous 150% strain in both the <i>x</i>- and <i>y</i>-directions. Furthermore, we engineered a highly ultraconformal electrocardiogram (ECG) detector onto a rabbit heart, providing accurate ECG signal monitoring. This strategy not only overcomes key fabrication challenges but also holds significant promise for advancing applications in implantable devices and biosensors.</p>","PeriodicalId":21,"journal":{"name":"ACS Nano","volume":"19 32","pages":"29316–29326"},"PeriodicalIF":16.0000,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bioinspired Bubble-Gated Strategy for Integrating a Polymer Fractal Micromesh toward Ultraconformal Electrocardiogram Monitoring\",\"authors\":\"Ke He, Kui Wang, Yuchen Yue, Shiqi Cao, Hanfei Gao*, Bo Zhang, Wei Li, Huixue Su, Ye Zhang, Wei Li, Jiangang Feng, Junchuan Yang*, Xuesong Zhang*, Lei Jiang and Yuchen Wu, \",\"doi\":\"10.1021/acsnano.5c05701\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >Ultraflexible polymer electronic devices with geometry engineering are highly promising for applications in conformal implantable medical devices owing to their strain tolerance, high charge carrier mobility, and biocompatibility. However, due to molecular entanglement of polymer chains and uncontrollable capillary flows, it remains a significant challenge to fabricate high-resolution, continuous, and uniform polymer patterns via solution processes, thus limiting the performance and scalability of their devices. Herein, we introduced a bioinspired bubble-gated strategy to directionally guide capillary flows for the fabrication of fractal micromeshes based on semiconductive polymers. Inspired by hierarchical liquid transport in the tree xylem, we developed a bubble-gated microfluidic system to regulate liquid distribution, facilitating the confined assembly of large-area, uniform polymer fractal micromeshes with a long-range order. Based on these micromeshes, we fabricated ultraflexible OECTs with stable performances under simultaneous 150% strain in both the <i>x</i>- and <i>y</i>-directions. Furthermore, we engineered a highly ultraconformal electrocardiogram (ECG) detector onto a rabbit heart, providing accurate ECG signal monitoring. This strategy not only overcomes key fabrication challenges but also holds significant promise for advancing applications in implantable devices and biosensors.</p>\",\"PeriodicalId\":21,\"journal\":{\"name\":\"ACS Nano\",\"volume\":\"19 32\",\"pages\":\"29316–29326\"},\"PeriodicalIF\":16.0000,\"publicationDate\":\"2025-08-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Nano\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acsnano.5c05701\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Nano","FirstCategoryId":"88","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsnano.5c05701","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Bioinspired Bubble-Gated Strategy for Integrating a Polymer Fractal Micromesh toward Ultraconformal Electrocardiogram Monitoring
Ultraflexible polymer electronic devices with geometry engineering are highly promising for applications in conformal implantable medical devices owing to their strain tolerance, high charge carrier mobility, and biocompatibility. However, due to molecular entanglement of polymer chains and uncontrollable capillary flows, it remains a significant challenge to fabricate high-resolution, continuous, and uniform polymer patterns via solution processes, thus limiting the performance and scalability of their devices. Herein, we introduced a bioinspired bubble-gated strategy to directionally guide capillary flows for the fabrication of fractal micromeshes based on semiconductive polymers. Inspired by hierarchical liquid transport in the tree xylem, we developed a bubble-gated microfluidic system to regulate liquid distribution, facilitating the confined assembly of large-area, uniform polymer fractal micromeshes with a long-range order. Based on these micromeshes, we fabricated ultraflexible OECTs with stable performances under simultaneous 150% strain in both the x- and y-directions. Furthermore, we engineered a highly ultraconformal electrocardiogram (ECG) detector onto a rabbit heart, providing accurate ECG signal monitoring. This strategy not only overcomes key fabrication challenges but also holds significant promise for advancing applications in implantable devices and biosensors.
期刊介绍:
ACS Nano, published monthly, serves as an international forum for comprehensive articles on nanoscience and nanotechnology research at the intersections of chemistry, biology, materials science, physics, and engineering. The journal fosters communication among scientists in these communities, facilitating collaboration, new research opportunities, and advancements through discoveries. ACS Nano covers synthesis, assembly, characterization, theory, and simulation of nanostructures, nanobiotechnology, nanofabrication, methods and tools for nanoscience and nanotechnology, and self- and directed-assembly. Alongside original research articles, it offers thorough reviews, perspectives on cutting-edge research, and discussions envisioning the future of nanoscience and nanotechnology.