增强现实视觉训练对脉络膜厚度和调节功能的直接影响：一项小样本研究。

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-08-07 DOI:10.1016/j.pdpdt.2025.104756

Guo-rui Hu , Zhi-xing Xu , Chang-feng Pan , Zheng-yang Tao , Hang Chu , Zong-yue Lv , Ze-feng Kang , Hong-wei Deng

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引用次数: 0

摘要

背景：增强现实（AR）视觉训练对脉络膜厚度（ChT）和调节设施（AF）的直接影响尚不清楚。AR技术与视力功能恢复模型结合在近视防控中的潜力有待进一步的实证验证。目的：本研究的目的是评估单次AR视觉训练结合视觉功能恢复模型对ChT和AF的直接效果。研究结果可能为优化这种跨学科数字治疗（DTx）方法提供证据，并评估其在近视干预中的潜力。方法：20名6 ~ 13岁的健康志愿者参与研究。参与者被随机分配到AR组（n=11）或空白对照组（n=9）。采用前瞻性自我控制设计，利用光学相干断层扫描血管造影评估训练前后ChT的变化。同时，在训练前后测量心房颤动。AR组接受了一次视觉训练，训练后的指标在五分钟内记录下来。空白对照组休息30分钟后重新测量相同的指标。结果：在单次AR视觉训练后，AR组在0-1 mm区域内的平均ChT显著降低，从332.85±79.00 μm降至324.11±73.52 μm （p = 0.007）。此外，AF从5.05±1.38 cpm显著增加到8.05±1.81 cpm （p = 0.004）。球当量与0 ~ 1 mm区域内的ChT变化呈显著正相关（r = 0.962,p = 0.009）。结论：单次AR视觉训练结合视觉功能恢复模型与短期内ChT降低和AF显著改善相关。这些研究结果表明，AR技术与DTx的整合具有作为近视干预策略的潜力，并为进一步优化数字治疗提供了新的方向。

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Immediate impact of augmented reality visual training on choroidal thickness and accommodative function: A small sample study

Background

The immediate effects of augmented reality (AR) visual training on choroidal thickness (ChT) and accommodative facility (AF) remain unclear. The potential of AR technology, when combined with vision function restoration models for myopia prevention and control requires further empirical validation.

Objective

The aim of this study is to evaluate the immediate effects of a single AR visual training session, integrated with a vision function restoration model, on ChT and AF. The findings may provide evidence to support the optimization of this interdisciplinary digital therapeutic (DTx) approach and assess its potential in myopia intervention.

Methods

Twenty healthy volunteers aged 6 to 13 years participated in the study. Participants were randomly assigned to an AR group (n = 11) or a blank control group (n = 9). A prospective self-controlled design was employed to assess changes in ChT before and after training using optical coherence tomography angiography. At the same time, AF was measured both before and after the training session. The AR group underwent a single session of visual training, with post-training metrics recorded within five minutes. The blank control group rested for 30 min before remeasuring the same metrics.

Results

Following a single AR visual training session, the AR group demonstrated a significant reduction in average ChT within the 0–1 mm zone, from 332.85 ± 79.00 µm to 324.11 ± 73.52 µm (p = 0.007). Additionally, AF significantly increased from 5.05±1.38 cpm to 8.05 ± 1.81 cpm (p = 0.004). A positive correlation was observed between spherical equivalent and the change in ChT within the 0–1 mm zone (r = 0.962, p = 0.009).

Conclusion

A single AR visual training session combined with a vision function restoration model was associated with a short-term decrease in ChT and a significant improvement in AF. These findings indicate that the integration of AR technology with DTx holds potential as a myopia intervention strategy and highlights a novel direction for further optimization of digital therapeutics.

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.