年龄和过敏原类型对慢性鼻炎患儿致敏变化的影响。

IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
Sucheera Nokkaew, Wanlapa Jotikasthira, Potjanee Kiewngam, Adithep Sawatchai, Watcharoot Kanchongkittiphon, Wiparat Manuyakorn
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引用次数: 0

摘要

背景:空气过敏原致敏评价有助于慢性鼻炎的诊断和治疗。目的:探讨鼻炎患儿过敏原致敏性随时间的变化。方法:对2009年至2019年间接受空气过敏原皮肤点刺试验(SPT)的慢性鼻炎患儿进行重新评估,并在2022年至2024年间进行第二次SPT。通过比较初始和重新评估的SPT结果来评估致敏变化。负转换器被定义为先前的阳性测试变为阴性。结果:在300名儿童(平均11.5岁)中,SPT阳性率从71.3%上升到83.7% (p结论:过敏原致敏模式随时间而变化,受过敏原类型和患者年龄的影响。重复检测可能是必要的,特别是对于鼻炎不受控制的儿童。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of age and allergen type on sensitization changes in children with chronic rhinitis.

Background: Aeroallergen sensitization evaluation aids in diagnosing and managing chronic rhinitis.

Objective: To investigate changes in allergen sensitization over time in children with rhinitis.

Methods: Children with chronic rhinitis who underwent aeroallergen skin prick tests (SPT) between 2009 and 2019 were re-evaluated with a second SPT between 2022 and 2024. Sensitization changes were assessed by comparing initial and re-evaluation SPT results. A negative converter was defined as a previously positive test that became negative.

Results: Among 300 children (mean age 11.5 years), positive SPT rates increased from 71.3 % to 83.7 % (p < 0.001). House dust mites (HDM) were the most common sensitization (77 %), followed by cockroaches (24 %). Sensitization patterns changed in 56.7 % of children. HDM sensitization increased across all age groups, while cat sensitization rose significantly in those initially tested before age 5. Negative conversion rates varied by allergen, highest for Careless Weed (85.7 %) and lowest for HDM (1.52 %). Children who became negative converters for Bermuda grass had smaller initial wheal sizes than those who remained positive (3 mm vs. 5.8 mm, p = 0.003).

Conclusion: Allergen sensitization patterns evolve over time, influenced by allergen type and patient age. Repeat testing may be necessary, especially for children with uncontrolled rhinitis.

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来源期刊
CiteScore
3.20
自引率
6.70%
发文量
276
审稿时长
62 days
期刊介绍: The purpose of the International Journal of Pediatric Otorhinolaryngology is to concentrate and disseminate information concerning prevention, cure and care of otorhinolaryngological disorders in infants and children due to developmental, degenerative, infectious, neoplastic, traumatic, social, psychiatric and economic causes. The Journal provides a medium for clinical and basic contributions in all of the areas of pediatric otorhinolaryngology. This includes medical and surgical otology, bronchoesophagology, laryngology, rhinology, diseases of the head and neck, and disorders of communication, including voice, speech and language disorders.
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