抑郁症和并发糖尿病患者的医疗资源利用:一项20年基于人群的倾向评分匹配队列研究

IF 3.7 2区 医学 Q1 PSYCHIATRY
General hospital psychiatry Pub Date : 2025-09-01 Epub Date: 2025-08-06 DOI:10.1016/j.genhosppsych.2025.08.004
Matthew Tsz Ho Ho, Joe Kwun Nam Chan, Heidi Ka Ying Lo, Catherine Zhiqian Fang, Corine Sau Man Wong, Krystal Chi Kei Lee, Wing Chung Chang
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引用次数: 0

摘要

背景:抑郁症合并糖尿病与糖尿病并发症的风险增加相关,导致大量的医疗保健支出。然而,先前调查糖尿病患者抑郁与医疗保健利用相关的研究受到重要限制的阻碍。我们研究了既往抑郁是否会增加偶发糖尿病患者的医疗保健利用和费用。方法:这项基于人群倾向评分(PS)匹配(1:10)的队列研究确定了2002年至2021年间香港12,165例已有抑郁症和偶发糖尿病患者(抑郁症-糖尿病组)和116,853例偶发糖尿病患者(糖尿病组),使用全港公共医疗服务病历数据库。ps匹配纳入了一系列综合协变量,包括年龄、性别、日历年期间、流域面积、身体和精神合并症以及药物处方。采用负二项回归比较各组之间的每患者年特定服务利用率,并按服务类型、性别和年龄组进行分层分析。结果:抑郁症-糖尿病组与糖尿病组相比,急诊期间医疗保健利用率显著提高38%(优势比1.16,95% CI[1.12-1.20];1906港元[243美元]对1648港元[210美元]),住院病人(1.47[1.27-1.72];17,333港元[2208美元]对12,356港元[1574美元]),门诊费用为1.29[1.27-1.31];11,974港元[1526美元]对8670港元[1105美元]),导致每位患者每年额外的医疗费用为8540港元。其他分析表明,在三个年龄组中,在精神科和非精神科资源中,在患有抑郁症和合并糖尿病的男性和女性中,与仅患有糖尿病的男性和女性相比,医疗保健利用率都有所增加。结论:与仅患有糖尿病的患者相比,既往抑郁并合并糖尿病患者的医疗资源利用率和成本增加的风险更高。有必要进一步研究有效的干预措施,以减轻与这两种情况有关的负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Healthcare resource utilization of people with depressive disorder and co-occurring incident diabetes mellitus: A 20-year population-based propensity score-matched cohort study.

Background: Depression with co-occurring diabetes is associated with elevated risk of diabetes complications, driving substantial healthcare expenditure. However, previous research investigating healthcare utilization associated with depression in patients with diabetes is hampered by important limitations. We examined whether pre-existing depression increased healthcare utilization and costs in patients with incident diabetes.

Method: This population-based propensity score (PS)-matched (1:10) cohort study identified 12,165 patients with pre-existing depression and incident-diabetes (depression-diabetes group) and 116,853 patients with incident-diabetes only (diabetes-only group) between 2002 and 2021 in Hong Kong, using territory-wide medical-record database of public healthcare services. A comprehensive array of covariates was included in PS-matching, comprising age, sex, calendar-year period, catchment-area, physical and psychiatric comorbidities, and medication prescriptions. Service-specific utilization per patient-year was compared by negative binomial regression between groups, with stratified analyses by service types, sex, and age groups.

Results: Depression-diabetes group was significantly associated with 38 % elevated healthcare utilization relative to diabetes-only group across emergency (Odds ratio 1.16, 95 %CI[1.12-1.20]; HK$1906[US$243] versus HK$1648[US$210]), inpatient (1.47[1.27-1.72]; HK$17,333[US$2208] versus HK$12,356[US$1574]), and outpatient services (1.29[1.27-1.31]; HK$11,974[US$1526] versus HK$8670[US$1105]), leading to additional HK$8540 annual healthcare costs per-patient. Additional analyses demonstrated that increased healthcare utilization was observed in both men and women with depression and co-occurring diabetes relative to their diabetes-only counterparts, across three age-groups, and in both psychiatric and non-psychiatric resources.

Conclusion: Patients with pre-existing depression and co-occurring incident-diabetes are at heightened risk for increased healthcare resource utilization and cost compared to diabetes-only patients. Further research on effective interventions is warranted to alleviate the burden associated with both conditions.

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来源期刊
General hospital psychiatry
General hospital psychiatry 医学-精神病学
CiteScore
9.60
自引率
2.90%
发文量
125
审稿时长
20 days
期刊介绍: General Hospital Psychiatry explores the many linkages among psychiatry, medicine, and primary care. In emphasizing a biopsychosocial approach to illness and health, the journal provides a forum for professionals with clinical, academic, and research interests in psychiatry''s role in the mainstream of medicine.
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