Highly efficient non-enzyme glucose sensing by multi-component CuCoNiFeSi alloy with feather-like CuxO

Extensive research focuses on developing cost-effective, high-performance electrochemical non-enzyme glucose sensors, particularly using nanocomposites of metal oxides and multi-component alloys. In this paper, a batch of nano-flaky Cu_xO decorated CuCoNiFeSi (Cu_xO@Cu/Fe) and CuCoNiSi (Cu_xO@Cu) electrode was developed by melt-spinning following by anodization. According to the results, the sensitivity of Cu_xO@Cu/Fe-25/35 for glucose detection in the lower (0–1 mM) and higher region (1–15 and 15–21 mM) is 2.544, 1.51 and 0.64 mA mM⁻¹ cm⁻², respectively. The limit of detection (LOD) was estimated to be 0.88 μM (signal noise ratio (S/N) = 3). Furthermore, the Cu_xO@Cu/Fe-25/35 possessed various merits, such as excellent selectivity, good reusability, acceptable reproducibility, satisfying long-term stability, and high tolerance to chloride ions. The enhanced performances of the Cu_xO@Cu/Fe-25/35 electrodes are attributable to the feather-like Cu_xO and synergistic effect between Cu_xO and Ni(Fe, Co)₃Si₂. The work provides a new pathway for detecting all glucose density by electrochemical non-enzymatic glucose sensor.

Graphical abstract