移植率比、等待名单生存和移植后生存的关联:移植受者指标科学登记的分析。

IF 1.7 3区 医学 Q2 SURGERY
Journal of Surgical Research Pub Date : 2025-10-01 Epub Date: 2025-08-07 DOI:10.1016/j.jss.2025.07.012
Faizaan Siddique, Sanath Patil, Nayeem Nasher, Daler Rahimov, Saaniya Farhan, Adam S Bodzin, John W Entwistle, Charles W Hoopes, Vakhtang Tchantchaleishvili
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引用次数: 0

摘要

简介:我们试图阐明移植率、等待名单生存率和移植后1年生存率在肝、肺和心脏移植项目之间的关系。方法:我们提取了2023年7月的移植受者科学登记处(SRTR)分级评分数据,反映了过去一年的三个指标:移植率比、等待名单生存率和移植后1年生存率。根据每个指标内的性能,五个层级从一个(最低)到五个(最高)不等。对肝、心、肺移植中心的评分指标进行比较。结果:在肺移植中心,较高的移植率评分与较低的候补生存率显著相关(r = -0.34, P < 0.01),而在心脏移植中心,这一趋势无显著性差异(r = -0.16, P = 0.08)。在心脏移植中心,较高的移植率评分与较高的移植后1年生存率相关(r = 0.22, P < 0.05)。虽然没有发现等待名单生存率和移植后生存率之间的直接关联,但所有三个SRTR分级评分指标的比较同时产生了对心脏和肺移植中心具有显著意义的回归平面(P分别< 0.01和P = 0.02)。在这些中心,较高的移植率评分与较低的等待名单生存率和较高的移植后1年生存率显著相关,尽管肝移植中心在这些指标之间没有表现出相关性。结论:移植率较高的心肺移植中心与较低的候补生存率和较高的移植后1年生存率相关,尽管肝移植中心的SRTR分级评分之间没有显着相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of Transplant Rate Ratio, Waitlist Survival, and Post-Transplant Survival: Analysis of Scientific Registry of Transplant Recipients Metrics.

Introduction: We sought to elucidate the relationship between transplant rate ratio, waitlist survival, and 1-y post-transplant survival across liver, lung, and heart transplant programs.

Methods: We extracted the Scientific Registry of Transplant Recipients (SRTR) tier rating data in July 2023 reflecting program performance over the past year in three metrics: transplant rate ratio, waitlist survival, and 1-y post-transplant survival. The five tiers ranged from one (lowest) to five (highest) in terms of performance within each metric. The rating metrics were compared across liver, heart, and lung transplant centers.

Results: A higher transplant rate ratio rating was significantly associated with lower waitlist survival rating among lung transplant centers (r = -0.34, P < 0.01), with a nonsignificant trend observed among heart transplant centers (r = -0.16, P = 0.08). A higher transplant rate ratio rating was associated with higher 1-y post-transplant survival rating among heart transplant centers (r = 0.22, P < 0.05). Although no direct association was found between waitlist survival rating and post-transplant survival rating, the comparison of all three SRTR tier rating metrics simultaneously produced regression planes that were significant for heart and lung transplant centers (P < 0.01 and P = 0.02, respectively). A higher transplant rate ratio rating was significantly associated with lower waitlist survival rating and higher 1-y post-transplant survival rating for these centers, although liver transplant centers exhibited no relationship among these metrics.

Conclusions: Heart and lung transplant centers with higher transplant rate were associated with lower waitlist survival and higher 1-y post-transplant survival, although the SRTR tier ratings were not significantly associated to each other among liver transplant centers.

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来源期刊
CiteScore
3.90
自引率
4.50%
发文量
627
审稿时长
138 days
期刊介绍: The Journal of Surgical Research: Clinical and Laboratory Investigation publishes original articles concerned with clinical and laboratory investigations relevant to surgical practice and teaching. The journal emphasizes reports of clinical investigations or fundamental research bearing directly on surgical management that will be of general interest to a broad range of surgeons and surgical researchers. The articles presented need not have been the products of surgeons or of surgical laboratories. The Journal of Surgical Research also features review articles and special articles relating to educational, research, or social issues of interest to the academic surgical community.
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