M Heqing Guo, M Hua Yuan, M Bowen Zhao, B Qiqi Hua, B Linhua Wang
{"title":"超声Z评分和肺动脉瓣/主动脉瓣直径比值提高胎儿主动脉瓣狭窄的预测价值。","authors":"M Heqing Guo, M Hua Yuan, M Bowen Zhao, B Qiqi Hua, B Linhua Wang","doi":"10.1002/jcu.70028","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the predictive value of the ultrasound-based Z score for the aortic valve (AV) diameter, pulmonary valve (PV) Z score, and the PV/AV ratio in diagnosing aortic stenosis (AS) in fetuses.</p><p><strong>Methods: </strong>A prospective study of 24 singleton fetuses with suspected AS who underwent two or more fetal echocardiograms was enrolled. Based on the pregnancy outcomes, the prenatal cases were divided into two groups: the AS group and the false-positive group. Electronic spatiotemporal image correlation (eSTIC) technology was used to measure AV and PV of all fetuses, and the AV and PV Z scores, along with the PV/AV ratio, were calculated, compared, and analyzed.</p><p><strong>Results: </strong>In the AS group, significant differences were found between the first and second echocardiograms regarding the AV Z score, PV Z score, and PV/AV ratio. In the false-positive group, only the PV Z score and PV/AV ratio showed significant differences. In the first echocardiogram, the AV Z score and PV/AV ratio significantly differed between the AS and false-positive groups. In the second echocardiogram, only the AV Z score showed differences. An AV Z score < -2.46 showed high sensitivity (89.5%) and specificity (100%) for AS diagnosis. When combined with a PV/AV ratio > 1.64, the predictive value increased.</p><p><strong>Conclusion: </strong>Fetal echocardiography with an AV Z score <-2.46 and a PV/AV ratio > 1.64 provides a higher predictive value for diagnosing AS in fetuses.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ultrasound-Based Z Score and Pulmonary Valve/Aortic Valve Diameter Ratio Improving the Predictive Value of Fetal Aortic Stenosis.\",\"authors\":\"M Heqing Guo, M Hua Yuan, M Bowen Zhao, B Qiqi Hua, B Linhua Wang\",\"doi\":\"10.1002/jcu.70028\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study aims to investigate the predictive value of the ultrasound-based Z score for the aortic valve (AV) diameter, pulmonary valve (PV) Z score, and the PV/AV ratio in diagnosing aortic stenosis (AS) in fetuses.</p><p><strong>Methods: </strong>A prospective study of 24 singleton fetuses with suspected AS who underwent two or more fetal echocardiograms was enrolled. Based on the pregnancy outcomes, the prenatal cases were divided into two groups: the AS group and the false-positive group. Electronic spatiotemporal image correlation (eSTIC) technology was used to measure AV and PV of all fetuses, and the AV and PV Z scores, along with the PV/AV ratio, were calculated, compared, and analyzed.</p><p><strong>Results: </strong>In the AS group, significant differences were found between the first and second echocardiograms regarding the AV Z score, PV Z score, and PV/AV ratio. In the false-positive group, only the PV Z score and PV/AV ratio showed significant differences. In the first echocardiogram, the AV Z score and PV/AV ratio significantly differed between the AS and false-positive groups. In the second echocardiogram, only the AV Z score showed differences. An AV Z score < -2.46 showed high sensitivity (89.5%) and specificity (100%) for AS diagnosis. When combined with a PV/AV ratio > 1.64, the predictive value increased.</p><p><strong>Conclusion: </strong>Fetal echocardiography with an AV Z score <-2.46 and a PV/AV ratio > 1.64 provides a higher predictive value for diagnosing AS in fetuses.</p>\",\"PeriodicalId\":15386,\"journal\":{\"name\":\"Journal of Clinical Ultrasound\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Ultrasound\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/jcu.70028\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ACOUSTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Ultrasound","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jcu.70028","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ACOUSTICS","Score":null,"Total":0}
Ultrasound-Based Z Score and Pulmonary Valve/Aortic Valve Diameter Ratio Improving the Predictive Value of Fetal Aortic Stenosis.
Objective: This study aims to investigate the predictive value of the ultrasound-based Z score for the aortic valve (AV) diameter, pulmonary valve (PV) Z score, and the PV/AV ratio in diagnosing aortic stenosis (AS) in fetuses.
Methods: A prospective study of 24 singleton fetuses with suspected AS who underwent two or more fetal echocardiograms was enrolled. Based on the pregnancy outcomes, the prenatal cases were divided into two groups: the AS group and the false-positive group. Electronic spatiotemporal image correlation (eSTIC) technology was used to measure AV and PV of all fetuses, and the AV and PV Z scores, along with the PV/AV ratio, were calculated, compared, and analyzed.
Results: In the AS group, significant differences were found between the first and second echocardiograms regarding the AV Z score, PV Z score, and PV/AV ratio. In the false-positive group, only the PV Z score and PV/AV ratio showed significant differences. In the first echocardiogram, the AV Z score and PV/AV ratio significantly differed between the AS and false-positive groups. In the second echocardiogram, only the AV Z score showed differences. An AV Z score < -2.46 showed high sensitivity (89.5%) and specificity (100%) for AS diagnosis. When combined with a PV/AV ratio > 1.64, the predictive value increased.
Conclusion: Fetal echocardiography with an AV Z score <-2.46 and a PV/AV ratio > 1.64 provides a higher predictive value for diagnosing AS in fetuses.
期刊介绍：
The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography.
The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents.
JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
