Alistair J Souch, Ian R Jones, Katherine H Shelton, Cerith S Waters
{"title":"妇女临床样本中的不良童年经历与生育和围产期心理健康结果","authors":"Alistair J Souch, Ian R Jones, Katherine H Shelton, Cerith S Waters","doi":"10.1016/j.jad.2025.120038","DOIUrl":null,"url":null,"abstract":"<p><p>Adverse Childhood Experiences (ACE) are associated with later life complications, including childbearing outcomes and episodes of mental ill-health. The perinatal period is a timepoint of vulnerability to the impacts of early life adversity, such as ACEs. We explored the association between maternal exposure to ACEs, entering parenthood, and episodes of mental ill-health during the perinatal period in a clinical sample with a mental health diagnosis to determine the increased vulnerability the perinatal period brings. Participants (N = 1494) were recruited across the UK, were aged 18 years or over, and female. Standardised self-report questionnaires ascertained demographic, parenthood, mental health, and ACE related information. Within this clinical sample, (N = 1010) women had given birth, and episodes of perinatal mental ill-health were assessed. Maternal childhood physical abuse was associated with an increased likelihood of having children, yet having divorced parents reduced this likelihood. In a clinical sub-sample of women who had children, physical abuse predicted a perinatal episode of bipolar disorder, sexual abuse a perinatal episode of anxiety disorders, and emotional neglect a perinatal episode of depressive disorders. CONCLUSIONS: Specific ACE exposure is associated with entering parenthood and episodes of mental ill-health during the perinatal period. This highlights a moment in the human lifespan when women who have experienced early adversity may be particularly vulnerable; the findings therefore have potential implications for the resourcing of specialist clinical services.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"120038"},"PeriodicalIF":4.9000,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adverse Childhood Experiences (ACEs) and childbearing and perinatal mental health outcomes in a clinical sample of women.\",\"authors\":\"Alistair J Souch, Ian R Jones, Katherine H Shelton, Cerith S Waters\",\"doi\":\"10.1016/j.jad.2025.120038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Adverse Childhood Experiences (ACE) are associated with later life complications, including childbearing outcomes and episodes of mental ill-health. The perinatal period is a timepoint of vulnerability to the impacts of early life adversity, such as ACEs. We explored the association between maternal exposure to ACEs, entering parenthood, and episodes of mental ill-health during the perinatal period in a clinical sample with a mental health diagnosis to determine the increased vulnerability the perinatal period brings. Participants (N = 1494) were recruited across the UK, were aged 18 years or over, and female. Standardised self-report questionnaires ascertained demographic, parenthood, mental health, and ACE related information. Within this clinical sample, (N = 1010) women had given birth, and episodes of perinatal mental ill-health were assessed. Maternal childhood physical abuse was associated with an increased likelihood of having children, yet having divorced parents reduced this likelihood. In a clinical sub-sample of women who had children, physical abuse predicted a perinatal episode of bipolar disorder, sexual abuse a perinatal episode of anxiety disorders, and emotional neglect a perinatal episode of depressive disorders. CONCLUSIONS: Specific ACE exposure is associated with entering parenthood and episodes of mental ill-health during the perinatal period. This highlights a moment in the human lifespan when women who have experienced early adversity may be particularly vulnerable; the findings therefore have potential implications for the resourcing of specialist clinical services.</p>\",\"PeriodicalId\":14963,\"journal\":{\"name\":\"Journal of affective disorders\",\"volume\":\" \",\"pages\":\"120038\"},\"PeriodicalIF\":4.9000,\"publicationDate\":\"2025-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of affective disorders\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jad.2025.120038\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/6 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of affective disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jad.2025.120038","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/6 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Adverse Childhood Experiences (ACEs) and childbearing and perinatal mental health outcomes in a clinical sample of women.
Adverse Childhood Experiences (ACE) are associated with later life complications, including childbearing outcomes and episodes of mental ill-health. The perinatal period is a timepoint of vulnerability to the impacts of early life adversity, such as ACEs. We explored the association between maternal exposure to ACEs, entering parenthood, and episodes of mental ill-health during the perinatal period in a clinical sample with a mental health diagnosis to determine the increased vulnerability the perinatal period brings. Participants (N = 1494) were recruited across the UK, were aged 18 years or over, and female. Standardised self-report questionnaires ascertained demographic, parenthood, mental health, and ACE related information. Within this clinical sample, (N = 1010) women had given birth, and episodes of perinatal mental ill-health were assessed. Maternal childhood physical abuse was associated with an increased likelihood of having children, yet having divorced parents reduced this likelihood. In a clinical sub-sample of women who had children, physical abuse predicted a perinatal episode of bipolar disorder, sexual abuse a perinatal episode of anxiety disorders, and emotional neglect a perinatal episode of depressive disorders. CONCLUSIONS: Specific ACE exposure is associated with entering parenthood and episodes of mental ill-health during the perinatal period. This highlights a moment in the human lifespan when women who have experienced early adversity may be particularly vulnerable; the findings therefore have potential implications for the resourcing of specialist clinical services.
期刊介绍:
The Journal of Affective Disorders publishes papers concerned with affective disorders in the widest sense: depression, mania, mood spectrum, emotions and personality, anxiety and stress. It is interdisciplinary and aims to bring together different approaches for a diverse readership. Top quality papers will be accepted dealing with any aspect of affective disorders, including neuroimaging, cognitive neurosciences, genetics, molecular biology, experimental and clinical neurosciences, pharmacology, neuroimmunoendocrinology, intervention and treatment trials.