{"title":"中国老年人内脏脂肪指数与高血压发生风险的关系：一项前瞻性队列研究。","authors":"Datian Gao, Xuejiao Chen, Dechen Liu, Donghai Su, Yulin Cheng, Yufang Cui, Wanli Hu, Zihao Li, Gefei Li, Xiaoke Zhang, Haiyun Gao, Songhe Shi","doi":"10.1007/s40292-025-00734-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The Chinese visceral adiposity index (CVAI), a favorable surrogate index for assessing visceral fat distribution and function, has been proven to be associated with various conditions, including diabetes mellitus, cardiovascular diseases, and strokes. Nevertheless, evidence on the association of CVAI with the risk of incident hypertension among older adults is limited.</p><p><strong>Aim: </strong>This study aimed to explore the association between CVAI and the risk of incident hypertension among older adults.</p><p><strong>Methods: </strong>Data were collected from the annual health examination dataset in Xinzheng, Henan Province from 2018 to 2023. A total of 10,353 participants aged ≥ 60 years were included. Cox proportional hazard models were used to examine the association between CVAI and the risk of incident hypertension by using hazard ratios (HRs) and 95% confidence intervals (CIs). Subgroup and sensitivity analyses were performed to confirm the association's robustness. Additionally, the restricted cubic spline (RCS) was used to fit the dose-response association between CVAI and the risk of incident hypertension.</p><p><strong>Results: </strong>During a median of 2.72 years of follow-up, hypertension developed in 6990 participants. In the fully-adjusted model, compared with participants in the tertile 1 of CVAI, the tertile 3 (HR = 1.26, 95% CI: 1.19-1.34) of CVAI was associated with an increased risk of incident hypertension and per standard deviation (SD) increase was associated with a 12% (HR = 1.12, 95% CI: 1.09-1.15) increased risk of incident hypertension. Similar significant associations were observed in subgroup and sensitivity analyses. Additionally, the RCS analysis showed a significant dose-response association of CVAI with the risk of incident hypertension (P overall < 0.001 and P nonlinear = 0.238).</p><p><strong>Conclusions: </strong>These results suggested a positive association between CVAI and the risk of incident hypertension among older adults.</p>","PeriodicalId":12890,"journal":{"name":"High Blood Pressure & Cardiovascular Prevention","volume":" ","pages":"553-562"},"PeriodicalIF":2.9000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association Between Chinese Visceral Adiposity Index and Risk of Incident Hypertension Among Older Adults: A Prospective Cohort Study.\",\"authors\":\"Datian Gao, Xuejiao Chen, Dechen Liu, Donghai Su, Yulin Cheng, Yufang Cui, Wanli Hu, Zihao Li, Gefei Li, Xiaoke Zhang, Haiyun Gao, Songhe Shi\",\"doi\":\"10.1007/s40292-025-00734-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The Chinese visceral adiposity index (CVAI), a favorable surrogate index for assessing visceral fat distribution and function, has been proven to be associated with various conditions, including diabetes mellitus, cardiovascular diseases, and strokes. Nevertheless, evidence on the association of CVAI with the risk of incident hypertension among older adults is limited.</p><p><strong>Aim: </strong>This study aimed to explore the association between CVAI and the risk of incident hypertension among older adults.</p><p><strong>Methods: </strong>Data were collected from the annual health examination dataset in Xinzheng, Henan Province from 2018 to 2023. A total of 10,353 participants aged ≥ 60 years were included. Cox proportional hazard models were used to examine the association between CVAI and the risk of incident hypertension by using hazard ratios (HRs) and 95% confidence intervals (CIs). Subgroup and sensitivity analyses were performed to confirm the association's robustness. Additionally, the restricted cubic spline (RCS) was used to fit the dose-response association between CVAI and the risk of incident hypertension.</p><p><strong>Results: </strong>During a median of 2.72 years of follow-up, hypertension developed in 6990 participants. In the fully-adjusted model, compared with participants in the tertile 1 of CVAI, the tertile 3 (HR = 1.26, 95% CI: 1.19-1.34) of CVAI was associated with an increased risk of incident hypertension and per standard deviation (SD) increase was associated with a 12% (HR = 1.12, 95% CI: 1.09-1.15) increased risk of incident hypertension. Similar significant associations were observed in subgroup and sensitivity analyses. Additionally, the RCS analysis showed a significant dose-response association of CVAI with the risk of incident hypertension (P overall < 0.001 and P nonlinear = 0.238).</p><p><strong>Conclusions: </strong>These results suggested a positive association between CVAI and the risk of incident hypertension among older adults.</p>\",\"PeriodicalId\":12890,\"journal\":{\"name\":\"High Blood Pressure & Cardiovascular Prevention\",\"volume\":\" \",\"pages\":\"553-562\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"High Blood Pressure & Cardiovascular Prevention\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s40292-025-00734-9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/9 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"PERIPHERAL VASCULAR DISEASE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"High Blood Pressure & Cardiovascular Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40292-025-00734-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/9 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
Association Between Chinese Visceral Adiposity Index and Risk of Incident Hypertension Among Older Adults: A Prospective Cohort Study.
Introduction: The Chinese visceral adiposity index (CVAI), a favorable surrogate index for assessing visceral fat distribution and function, has been proven to be associated with various conditions, including diabetes mellitus, cardiovascular diseases, and strokes. Nevertheless, evidence on the association of CVAI with the risk of incident hypertension among older adults is limited.
Aim: This study aimed to explore the association between CVAI and the risk of incident hypertension among older adults.
Methods: Data were collected from the annual health examination dataset in Xinzheng, Henan Province from 2018 to 2023. A total of 10,353 participants aged ≥ 60 years were included. Cox proportional hazard models were used to examine the association between CVAI and the risk of incident hypertension by using hazard ratios (HRs) and 95% confidence intervals (CIs). Subgroup and sensitivity analyses were performed to confirm the association's robustness. Additionally, the restricted cubic spline (RCS) was used to fit the dose-response association between CVAI and the risk of incident hypertension.
Results: During a median of 2.72 years of follow-up, hypertension developed in 6990 participants. In the fully-adjusted model, compared with participants in the tertile 1 of CVAI, the tertile 3 (HR = 1.26, 95% CI: 1.19-1.34) of CVAI was associated with an increased risk of incident hypertension and per standard deviation (SD) increase was associated with a 12% (HR = 1.12, 95% CI: 1.09-1.15) increased risk of incident hypertension. Similar significant associations were observed in subgroup and sensitivity analyses. Additionally, the RCS analysis showed a significant dose-response association of CVAI with the risk of incident hypertension (P overall < 0.001 and P nonlinear = 0.238).
Conclusions: These results suggested a positive association between CVAI and the risk of incident hypertension among older adults.
期刊介绍：
High Blood Pressure & Cardiovascular Prevention promotes knowledge, update and discussion in the field of hypertension and cardiovascular disease prevention, by providing a regular programme of independent review articles covering key aspects of the management of hypertension and cardiovascular diseases. The journal includes: Invited ''State of the Art'' reviews. Expert commentaries on guidelines, major trials, technical advances.Presentation of new intervention trials design.''Pros and Cons'' or round tables on controversial issues.Statements on guidelines from hypertension and cardiovascular scientific societies.Socio-economic issues.Cost/benefit in prevention of cardiovascular diseases.Monitoring of healthcare systems.News and views from the Italian Society of Hypertension (including abstracts).All manuscripts are subject to peer review by international experts. Letters to the editor are welcomed and will be considered for publication.
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