用商业PCR检测MRSA载体分析合并样本的高诊断准确性。

IF 1.8 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2025-12-01 Epub Date: 2025-08-05 DOI:10.1016/j.diagmicrobio.2025.117031

Ditte Bang Oturai, Jonas Bredtoft Boel, Jette Bangsborg, Frederik Emil Mandix, Barbara Juliane Holzknecht

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引用次数: 0

摘要

我们评估了两代造父变星Xpert MRSA检测的诊断准确性，使用来自4,519例患者的汇总样本来检测低流行人群中的MRSA携带。Xpert MRSA NxG试剂盒具有较高的准确性，包括95%的灵敏度和99%的特异性。这支持聚合PCR作为一种资源高效的方法。

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High diagnostic accuracy of pooled samples analysed with a commercial PCR for detecting MRSA carriage.

We evaluated the diagnostic accuracy of two Cepheid Xpert MRSA assay generations using pooled samples from 4,519 patients to detect MRSA carriage in a low-prevalence population. High accuracy, including 95 % sensitivity and 99 % specificity was shown for the Xpert MRSA NxG kit. This supports pooled PCR as a resource-efficient method.

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.