不宁腿综合症和桥本甲状腺炎。

IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY
Arif Tolga Sönmez, Hüseyin Demirci
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引用次数: 0

摘要

背景:据推测,甲状腺激素和多巴胺能活性之间的不平衡可能导致不宁腿综合征(RLS)的发展。本研究旨在评估与健康对照相比,桥本甲状腺炎患者RLS的发生率和严重程度,重点关注甲状腺激素替代疗法的潜在影响。方法:连续120例桥本甲状腺炎患者80例(未治疗40例,正在治疗40例)和健康对照40例纳入研究。根据国际不宁腿综合征研究组(IRLSSG)的诊断标准评估RLS症状。使用不宁腿综合征严重程度评定量表(RLS-SRS)评估症状严重程度。结果:与健康对照组相比,桥本甲状腺炎患者的RLS症状和RLS- srs评分明显更高(p)。结论:我们的研究结果表明,未经治疗的桥本甲状腺炎患者的RLS更为普遍和严重。此外,甲状腺激素替代疗法可能对降低该人群中RLS的发生率和严重程度具有保护作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Restless legs syndrome and hashimoto's thyroiditis.

Background: It has been hypothesized that an imbalance between thyroid hormones and dopaminergic activity may contribute to the development of Restless legs syndrome (RLS). This study aimed to evaluate the incidence and severity of RLS in patients with Hashimoto's thyroiditis compared to healthy controls, with a focus on the potential impact of thyroid hormone replacement therapy.

Methods: A total of 120 consecutive patients, 80 with Hashimoto's thyroiditis (40 untreated, 40 under treatment) and 40 healthy controls, were included in the study. RLS symptoms were assessed based on the International Restless Legs Syndrome Study Group (IRLSSG) diagnostic criteria. Symptom severity was evaluated using the Restless Legs Syndrome Severity Rating Scale (RLS-SRS).

Results: RLS symptoms and RLS-SRS scores were significantly higher in patients with Hashimoto's thyroiditis compared to healthy controls (p < 0.01). The untreated group showed a significantly higher RLS incidence and symptom severity than both the treated group and controls (p < 0.001). No significant difference was observed between the treated Hashimoto's group and the control group. Additionally, RLS severity was associated with a longer duration of Hashimoto's disease (p = 0.03).

Conclusion: The results of our study suggest that RLS is more prevalent and severe in patients with untreated Hashimoto's thyroiditis. Furthermore, thyroid hormone replacement therapy may have a protective role in reducing both the incidence and severity of RLS in this population.

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来源期刊
Acta neurologica Belgica
Acta neurologica Belgica 医学-临床神经学
CiteScore
4.20
自引率
3.70%
发文量
300
审稿时长
6-12 weeks
期刊介绍: Peer-reviewed and published quarterly, Acta Neurologica Belgicapresents original articles in the clinical and basic neurosciences, and also reports the proceedings and the abstracts of the scientific meetings of the different partner societies. The contents include commentaries, editorials, review articles, case reports, neuro-images of interest, book reviews and letters to the editor. Acta Neurologica Belgica is the official journal of the following national societies: Belgian Neurological Society Belgian Society for Neuroscience Belgian Society of Clinical Neurophysiology Belgian Pediatric Neurology Society Belgian Study Group of Multiple Sclerosis Belgian Stroke Council Belgian Headache Society Belgian Study Group of Neuropathology
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