{"title":"磁共振引导聚焦超声(MRgFUS)丘脑切开术在特发性震颤和震颤显性帕金森病中的目标的概率映射:来自德国队列的见解。","authors":"Jonas Krauss,Neeraj Upadhyay,Veronika Purrer,Valeri Borger,Marcel Daamen,Hannah Weiland,Angelika Maurer,Carsten Schmeel,Alexander Radbruch,Markus Essler,Ullrich Wüllner,Henning Boecker","doi":"10.1002/mds.70003","DOIUrl":null,"url":null,"abstract":"Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).","PeriodicalId":213,"journal":{"name":"Movement Disorders","volume":"95 1","pages":""},"PeriodicalIF":7.6000,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Probabilistic Mapping of Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor-Dominant Parkinson's Disease: Insights from a German Cohort.\",\"authors\":\"Jonas Krauss,Neeraj Upadhyay,Veronika Purrer,Valeri Borger,Marcel Daamen,Hannah Weiland,Angelika Maurer,Carsten Schmeel,Alexander Radbruch,Markus Essler,Ullrich Wüllner,Henning Boecker\",\"doi\":\"10.1002/mds.70003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).\",\"PeriodicalId\":213,\"journal\":{\"name\":\"Movement Disorders\",\"volume\":\"95 1\",\"pages\":\"\"},\"PeriodicalIF\":7.6000,\"publicationDate\":\"2025-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Movement Disorders\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/mds.70003\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Movement Disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/mds.70003","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
磁共振引导聚焦超声(MRgFUS)的精确定位对于原发性震颤和震颤显性帕金森病的有效震颤控制至关重要,因为微小的偏差可能会降低疗效或引起副作用。在我们的队列中,甜点在蒙特利尔神经学研究所(MNI)坐标x = -12.4, y = -17.5, z = -1.7 (ET)和x = -13.4, y = -19.8, z = -3.0 (TDPD)被确定。
Probabilistic Mapping of Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor-Dominant Parkinson's Disease: Insights from a German Cohort.
Precise targeting in magnetic resonance-guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor-dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = -12.4, y = -17.5, z = -1.7 (ET) and x = -13.4, y = -19.8, z = -3.0 (TDPD).
期刊介绍:
Movement Disorders publishes a variety of content types including Reviews, Viewpoints, Full Length Articles, Historical Reports, Brief Reports, and Letters. The journal considers original manuscripts on topics related to the diagnosis, therapeutics, pharmacology, biochemistry, physiology, etiology, genetics, and epidemiology of movement disorders. Appropriate topics include Parkinsonism, Chorea, Tremors, Dystonia, Myoclonus, Tics, Tardive Dyskinesia, Spasticity, and Ataxia.