{"title":"伤口敷料的研究进展:单胚根提取物的生物功能化纳米颗粒。","authors":"Rajeshreeba A Jadeja, Suranjana V Mayani","doi":"10.1177/15347346251365421","DOIUrl":null,"url":null,"abstract":"<p><p>Wound healing is a complex biological process that can be significantly impaired by numerous factors, resulting in chronic wounds. Recent advancements in nanotechnology have demonstrated the potential of biofunctionalized nanoparticles to improve wound healing. This review examines the methodology and application of biofunctionalized nanoparticles derived from <i>Butea monosperma</i> root extract, incorporated into electro spun nanofibers, presenting a novel approach for advanced wound dressings. This review examines the extraction process, nanoparticle synthesis, electrospinning techniques, and the assessment of the therapeutic properties of the nanofibers. In vitro and in vivo studies demonstrate the efficacy of this approach in promoting wound healing, highlighting significant antibacterial activity and improved tissue regeneration. Future research and clinical application directions are also examined.</p>","PeriodicalId":94229,"journal":{"name":"The international journal of lower extremity wounds","volume":" ","pages":"15347346251365421"},"PeriodicalIF":1.5000,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Review on Advancements in Wound Dressing: Biofunctionalized Nanoparticles from <i>Butea monosperma</i> Root Extract.\",\"authors\":\"Rajeshreeba A Jadeja, Suranjana V Mayani\",\"doi\":\"10.1177/15347346251365421\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Wound healing is a complex biological process that can be significantly impaired by numerous factors, resulting in chronic wounds. Recent advancements in nanotechnology have demonstrated the potential of biofunctionalized nanoparticles to improve wound healing. This review examines the methodology and application of biofunctionalized nanoparticles derived from <i>Butea monosperma</i> root extract, incorporated into electro spun nanofibers, presenting a novel approach for advanced wound dressings. This review examines the extraction process, nanoparticle synthesis, electrospinning techniques, and the assessment of the therapeutic properties of the nanofibers. In vitro and in vivo studies demonstrate the efficacy of this approach in promoting wound healing, highlighting significant antibacterial activity and improved tissue regeneration. Future research and clinical application directions are also examined.</p>\",\"PeriodicalId\":94229,\"journal\":{\"name\":\"The international journal of lower extremity wounds\",\"volume\":\" \",\"pages\":\"15347346251365421\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The international journal of lower extremity wounds\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/15347346251365421\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The international journal of lower extremity wounds","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/15347346251365421","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Review on Advancements in Wound Dressing: Biofunctionalized Nanoparticles from Butea monosperma Root Extract.
Wound healing is a complex biological process that can be significantly impaired by numerous factors, resulting in chronic wounds. Recent advancements in nanotechnology have demonstrated the potential of biofunctionalized nanoparticles to improve wound healing. This review examines the methodology and application of biofunctionalized nanoparticles derived from Butea monosperma root extract, incorporated into electro spun nanofibers, presenting a novel approach for advanced wound dressings. This review examines the extraction process, nanoparticle synthesis, electrospinning techniques, and the assessment of the therapeutic properties of the nanofibers. In vitro and in vivo studies demonstrate the efficacy of this approach in promoting wound healing, highlighting significant antibacterial activity and improved tissue regeneration. Future research and clinical application directions are also examined.