{"title":"左心室辅助装置在心力衰竭管理中的应用:单中心经验。","authors":"Sam Karem, Rajasekhar S R Malyala, Sibu Saha","doi":"10.1055/a-2536-9161","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Heart failure is a prevalent health care issue in the United States. While most cases of heart failure can be managed medically, intractable cases benefit from a left ventricular assist device (LVAD).</p><p><strong>Aim: </strong>The aim of this study is to review the outcomes of LVAD therapy at the University of Kentucky.</p><p><strong>Materials and methods: </strong>Data received from University of Kentucky Hospital. We received Institutional Review Board approval to review patient records admitted for LVAD implantation from January 1, 2017, to December 31, 2021.</p><p><strong>Results: </strong>After reviewing records, we had 127 eligible LVAD patients with an age range of 18 to 83 years, with 87% of recipients being white, 12.5% being black, 81% male, and 19% female. Results show the average length of admission for patients receiving LVAD is 41 days. Quality of life is reported using the New York Heart Association (NYHA) classification at follow-up, which shows 6 patients in Class I, 52 patients progressing to Class II, 21 patients to class III; other patients were deceased before discharge or did not go below class IV heart failure. Prior to 2021, there were 105 patients and 65 patients were alive at 2 years follow-up, and 18 out of 23 patients who received LVAD after 2021 are still living. For postoperative complications, 26% developed stroke, 24.4% developed gastrointestinal bleeding, 26% developed renal failure, 44.8% developed respiratory failure, 37% developed driveline infection, 14.2% developed right ventricular dysfunction/failure, and 20.4% developed an LVAD complication.</p><p><strong>Conclusion: </strong>LVAD has been implemented to manage advanced heart failure and improve quality of life.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"34 3","pages":"220-225"},"PeriodicalIF":0.9000,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12324851/pdf/","citationCount":"0","resultStr":"{\"title\":\"Left Ventricular Assist Device in the Management of Heart Failure: A Single-Center Experience.\",\"authors\":\"Sam Karem, Rajasekhar S R Malyala, Sibu Saha\",\"doi\":\"10.1055/a-2536-9161\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Heart failure is a prevalent health care issue in the United States. While most cases of heart failure can be managed medically, intractable cases benefit from a left ventricular assist device (LVAD).</p><p><strong>Aim: </strong>The aim of this study is to review the outcomes of LVAD therapy at the University of Kentucky.</p><p><strong>Materials and methods: </strong>Data received from University of Kentucky Hospital. We received Institutional Review Board approval to review patient records admitted for LVAD implantation from January 1, 2017, to December 31, 2021.</p><p><strong>Results: </strong>After reviewing records, we had 127 eligible LVAD patients with an age range of 18 to 83 years, with 87% of recipients being white, 12.5% being black, 81% male, and 19% female. Results show the average length of admission for patients receiving LVAD is 41 days. Quality of life is reported using the New York Heart Association (NYHA) classification at follow-up, which shows 6 patients in Class I, 52 patients progressing to Class II, 21 patients to class III; other patients were deceased before discharge or did not go below class IV heart failure. Prior to 2021, there were 105 patients and 65 patients were alive at 2 years follow-up, and 18 out of 23 patients who received LVAD after 2021 are still living. For postoperative complications, 26% developed stroke, 24.4% developed gastrointestinal bleeding, 26% developed renal failure, 44.8% developed respiratory failure, 37% developed driveline infection, 14.2% developed right ventricular dysfunction/failure, and 20.4% developed an LVAD complication.</p><p><strong>Conclusion: </strong>LVAD has been implemented to manage advanced heart failure and improve quality of life.</p>\",\"PeriodicalId\":13798,\"journal\":{\"name\":\"International Journal of Angiology\",\"volume\":\"34 3\",\"pages\":\"220-225\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-03-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12324851/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Angiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/a-2536-9161\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"PERIPHERAL VASCULAR DISEASE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Angiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2536-9161","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
Left Ventricular Assist Device in the Management of Heart Failure: A Single-Center Experience.
Background: Heart failure is a prevalent health care issue in the United States. While most cases of heart failure can be managed medically, intractable cases benefit from a left ventricular assist device (LVAD).
Aim: The aim of this study is to review the outcomes of LVAD therapy at the University of Kentucky.
Materials and methods: Data received from University of Kentucky Hospital. We received Institutional Review Board approval to review patient records admitted for LVAD implantation from January 1, 2017, to December 31, 2021.
Results: After reviewing records, we had 127 eligible LVAD patients with an age range of 18 to 83 years, with 87% of recipients being white, 12.5% being black, 81% male, and 19% female. Results show the average length of admission for patients receiving LVAD is 41 days. Quality of life is reported using the New York Heart Association (NYHA) classification at follow-up, which shows 6 patients in Class I, 52 patients progressing to Class II, 21 patients to class III; other patients were deceased before discharge or did not go below class IV heart failure. Prior to 2021, there were 105 patients and 65 patients were alive at 2 years follow-up, and 18 out of 23 patients who received LVAD after 2021 are still living. For postoperative complications, 26% developed stroke, 24.4% developed gastrointestinal bleeding, 26% developed renal failure, 44.8% developed respiratory failure, 37% developed driveline infection, 14.2% developed right ventricular dysfunction/failure, and 20.4% developed an LVAD complication.
Conclusion: LVAD has been implemented to manage advanced heart failure and improve quality of life.