光学雾化是降低近视过高估计的有效方法。

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-08-05 DOI:10.1016/j.pdpdt.2025.104751

Jiajia Lin , Ting Chen , Zequn Lin , Xinyao Xiong , Yinhe Chen , Yang Yu , Luoming Huang

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引用次数: 0

摘要

背景：本研究旨在探讨光学雾化控制调节的效果，并评价其在降低青少年近视高估中的效果，为临床屈光测量提供科学依据。方法：共招募了142名17 ~ 23岁的年轻人（284只眼）。在基线、光学雾化和睫状体麻痹三种情况下，使用开场自折射仪和部分相干干涉测量屈光状态和眼部生物特征参数。采用+2.00 D球面镜片配戴20分钟致光学雾化，0.5%复方热带酰胺-苯肾上腺素滴眼液致睫状体麻痹。根据眼球等效值（SE）与基线测量值的差值是否≥0.50 d，将眼分为高估和非高估近视组。分析三种情况下眼球等效值和晶状体厚度的变化，并计算雾诱导调节控制的效率。结果：在高估近视组（82只眼）中，光学雾化使调节能力较基线平均降低0.28±0.37 D (p < 0.001)，占单眼麻痹效果（0.76±0.29 D）的36.84%。在整个样本眼中，雾化使调节能力降低了0.07±0.34 D (p < 0.001)，相当于单眼麻痹效果（0.32±0.37 D）的21.88%。光学雾化后晶状体厚度无明显变化，而睫状体麻痹显著降低晶状体厚度(高估近视组：-0.07±0.10 mm, p = 0.003；总：-0.05±0.19 mm, p < 0.001)。结论：光学雾化可有效抑制年轻人不必要的调节反应，显著降低近视高估，对有明显近视高估的人群效果尤为显著。虽然光学雾化在放松调节方面不如睫状体麻痹有效，但它在易于使用，非侵入性和良好的耐受性方面具有优势，使其在临床屈光测量中非常适用。

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Optical fogging is an effective method of reducing overestimation of myopia

Background

This study aimed to investigate the effectiveness of optical fogging in controlling accommodation and to evaluate its efficiency in reducing myopic overestimation among young adults, with the goal of providing scientific evidence for clinical refractive measurement.

Methods

A total of 142 young adults aged 17 to 23 years (284 eyes) were enrolled. Refractive status and ocular biometric parameters were measured using open-field autorefractor and partial coherence interferometry under three conditions: baseline, optical fogging, and cycloplegia. Optical fogging was induced by wearing +2.00 D spherical lenses for 20 min, while cycloplegia was induced using 0.5 % compound tropicamide-phenylephrine eye drops. Eyes were categorized into overestimated and non-overestimated myopia groups based on whether the difference in spherical equivalent (SE) between cycloplegic and baseline measurements was ≥0.50 D. Changes in SE and lens thickness under the three conditions were analyzed, and the efficiency of optical fogging-induced accommodative control was calculated.

Results

In the overestimated myopia group (82 eyes), optical fogging reduced accommodation by an average of 0.28 ± 0.37 D compared to baseline (p < 0.001), accounting for 36.84 % of the effect of cycloplegia (0.76 ± 0.29 D). In the total sample eyes, optical fogging reduced accommodation by 0.07 ± 0.34 D (p < 0.001), which corresponded to 21.88 % of the cycloplegic effect (0.32 ± 0.37 D). Lens thickness showed no significant change after optical fogging (all p > 0.05).

Conclusions

Optical fogging effectively suppresses unnecessary accommodative responses in young adults, significantly reducing myopic overestimation, with particularly pronounced effects in those with notable myopic overestimation. Although optical fogging is less effective than cycloplegia in relaxing accommodation, it offers advantages in terms of ease of use, non-invasiveness, and good tolerance, making it highly applicable in clinical refractive measurement.

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.