接受体外膜氧合的婴儿先天性膈疝的手术时机：一项荟萃分析。

IF 1.6 3区医学 Q2 PEDIATRICS

Pediatric Surgery International Pub Date : 2025-08-05 DOI:10.1007/s00383-025-06146-z

Minhua Lin, Hao Wu, Jiachi Liao, Ziyin Lyu, Le Li

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引用次数: 0

摘要

关于接受体外膜氧合（ECMO）的婴儿先天性膈疝手术的时机存在争议。我们进行了一项荟萃分析，研究了接受ECMO的婴儿先天性膈疝（CDH）手术的最佳时机。与晚期ECMO手术相比，早期ECMO修复手术降低了死亡率(OR, 0.51；95% ci 0.30-0.87；P = 0.01)和术后出血率(OR, 0.25；95% ci 0.11-0.54；P = 0.0004)，缩短ECMO持续时间(MD, - 2.15；95% Cl, - 3.20 ~ - 1.09；P

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The timing of surgery for congenital diaphragmatic hernia in infants receiving extracorporeal membrane oxygenation: a meta-analysis.

There is controversy regarding the timing of congenital diaphragmatic hernia surgery in infants receiving extracorporeal membrane oxygenation (ECMO). We conducted a meta-analysis of trials examining the optimal timing of surgery for congenital diaphragmatic hernia (CDH) in infants receiving ECMO. Compared to late surgery with ECMO, early repair surgery with ECMO reduced mortality (OR, 0.51; 95% CI 0.30-0.87; P = 0.01) and postoperative bleeding rates (OR, 0.25; 95% CI 0.11-0.54; P = 0.0004) and shortened ECMO duration (MD, - 2.15; 95% Cl, - 3.20 to - 1.09; P < 0.0001) and duration of hospitalization (MD, - 29.07; 95% Cl, - 44.55 to - 12.59; P = 0.0005). There were no significant differences in ventilator duration (MD, - 15.98; 95% CI, - 35.76 to 3.80; P = 0.11). For infants with CDH receiving ECMO, we recommend early repair surgery. Levels of evidence: Level III.

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来源期刊

Pediatric Surgery International 医学-外科

CiteScore

3.00

自引率

5.60%

发文量

215

审稿时长

3-6 weeks

期刊介绍： Pediatric Surgery International is a journal devoted to the publication of new and important information from the entire spectrum of pediatric surgery. The major purpose of the journal is to promote postgraduate training and further education in the surgery of infants and children. The contents will include articles in clinical and experimental surgery, as well as related fields. One section of each issue is devoted to a special topic, with invited contributions from recognized authorities. Other sections will include: -Review articles- Original articles- Technical innovations- Letters to the editor