小柴胡汤加减汤联合丙戊酸钠治疗脑膜炎相关性癫痫疗效观察。

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Yiming Li, Xiao Zhang, Maoyun Wang, Shuai Meng, Fagen Li
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引用次数: 0

摘要

脑膜炎是一种神经系统疾病,严重时可引起癫痫。本研究分析小柴胡汤加减汤联合丙戊酸钠治疗脑膜炎相关癫痫的疗效。将2022年6月至2024年6月期间100例脑膜炎相关癫痫患者随机分为对照组(n=50)和研究组(n=50)。两组患者均给予丙戊酸钠治疗,研究组患者加用柴胡汤加减汤治疗。评价两组患者中医症状(TCMS)评分、脑脊液恢复正常比例、神经学因素、炎症因素、免疫指标、生活质量评分、功能区评分、临床疗效及不良反应发生率。两组治疗后的结果均优于治疗前。治疗后,对照组患者TCMS评分、脑脊液恢复正常比例、神经因素、免疫指标、生活质量评分、功能区评分、临床疗效均高于对照组,对照组患者炎症因素及不良反应发生率均低于对照组(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Observation on the efficacy of Xiao Chai Hu Tang plus minus Tang combined with sodium valproate in the treatment of meningitis-associated epilepsy.

Meningitis is a neurological condition that can be severe causing epilepsy. This study analyzed the efficacy of Xiao Chai Hu Tang plus minus Tang combined with sodium valproate in the treatment of meningitis-associated epilepsy. 100 patients with meningitis-associated epilepsy during June 2022 to June 2024 were randomised to control group (n=50) and study group (n=50). Both groups were treated with sodium valproate and study group was added Xiao Chai Hu Tang plus minus Tang treatment. To evaluate the traditional Chinese medicine symptom (TCMS) scores, cerebrospinal fluid returning to normal proportion, neurological factors, inflammatory factors, immune indicators, life qualities scores, functional area scores, clinical efficacy and adverse reactions incidence in both groups. All the results of the both groups post-therapy were better versus pre-therapy. Post-therapy, the TCMS scores, erebrospinal fluid returning to normal proportion, neurological factors, immune indicators, life qualities scores, functional area scores and clinical efficacy were above to control group, the inflammatory factors and adverse reactions incidence were below in study group (p<0.05). The efficacy of this combination therapy for the treatment of meningitis-associated epilepsy is accurate and has high clinical value.

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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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