Ahmad Matarneh, Sundus Sardar, Abdelrauof Akkari, Omar Salameh, Naman Trivedi, Muhammad Abdulbasit, Navin Verma, Ronald Miller, Nasrollah Ghahramani
{"title":"感染性心内膜炎模拟抗中性粒细胞-细胞质-抗体相关血管炎伴肾小球肾炎1例报告。","authors":"Ahmad Matarneh, Sundus Sardar, Abdelrauof Akkari, Omar Salameh, Naman Trivedi, Muhammad Abdulbasit, Navin Verma, Ronald Miller, Nasrollah Ghahramani","doi":"10.1186/s13256-025-05470-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Infective endocarditis occasionally presents with antineutrophil cytoplasmic antibody positivity, leading to diagnostic challenges and confusion, as it can be mislabeled antineutrophil-cytoplasmic-antibody-associated vasculitis. Distinguishing between these two factors is crucial for appropriate management.</p><p><strong>Case presentation: </strong>In this case report, we describe a 77-year-old White non-Hispanic male patient who initially presented with features suggestive of antineutrophil-cytoplasmic-antibody-associated vasculitis but was ultimately diagnosed with infective endocarditis.</p><p><strong>Conclusion: </strong>Our findings emphasize the need to rule out infective endocarditis in patients with suspected antineutrophil-cytoplasmic-antibody-associated vasculitis, as it can be the same, and management relies on different lines of therapy. Immunosuppression therapy can lead to devastating effects in patients with infective endocarditis.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"385"},"PeriodicalIF":0.8000,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12323207/pdf/","citationCount":"0","resultStr":"{\"title\":\"Infective endocarditis mimicking antineutrophil-cytoplasmic-antibody-associated vasculitis with glomerulonephritis: a case report.\",\"authors\":\"Ahmad Matarneh, Sundus Sardar, Abdelrauof Akkari, Omar Salameh, Naman Trivedi, Muhammad Abdulbasit, Navin Verma, Ronald Miller, Nasrollah Ghahramani\",\"doi\":\"10.1186/s13256-025-05470-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Infective endocarditis occasionally presents with antineutrophil cytoplasmic antibody positivity, leading to diagnostic challenges and confusion, as it can be mislabeled antineutrophil-cytoplasmic-antibody-associated vasculitis. Distinguishing between these two factors is crucial for appropriate management.</p><p><strong>Case presentation: </strong>In this case report, we describe a 77-year-old White non-Hispanic male patient who initially presented with features suggestive of antineutrophil-cytoplasmic-antibody-associated vasculitis but was ultimately diagnosed with infective endocarditis.</p><p><strong>Conclusion: </strong>Our findings emphasize the need to rule out infective endocarditis in patients with suspected antineutrophil-cytoplasmic-antibody-associated vasculitis, as it can be the same, and management relies on different lines of therapy. Immunosuppression therapy can lead to devastating effects in patients with infective endocarditis.</p>\",\"PeriodicalId\":16236,\"journal\":{\"name\":\"Journal of Medical Case Reports\",\"volume\":\"19 1\",\"pages\":\"385\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-08-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12323207/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s13256-025-05470-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s13256-025-05470-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Infective endocarditis mimicking antineutrophil-cytoplasmic-antibody-associated vasculitis with glomerulonephritis: a case report.
Background: Infective endocarditis occasionally presents with antineutrophil cytoplasmic antibody positivity, leading to diagnostic challenges and confusion, as it can be mislabeled antineutrophil-cytoplasmic-antibody-associated vasculitis. Distinguishing between these two factors is crucial for appropriate management.
Case presentation: In this case report, we describe a 77-year-old White non-Hispanic male patient who initially presented with features suggestive of antineutrophil-cytoplasmic-antibody-associated vasculitis but was ultimately diagnosed with infective endocarditis.
Conclusion: Our findings emphasize the need to rule out infective endocarditis in patients with suspected antineutrophil-cytoplasmic-antibody-associated vasculitis, as it can be the same, and management relies on different lines of therapy. Immunosuppression therapy can lead to devastating effects in patients with infective endocarditis.
期刊介绍：
JMCR is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. Reports should show one of the following: 1. Unreported or unusual side effects or adverse interactions involving medications 2. Unexpected or unusual presentations of a disease 3. New associations or variations in disease processes 4. Presentations, diagnoses and/or management of new and emerging diseases 5. An unexpected association between diseases or symptoms 6. An unexpected event in the course of observing or treating a patient 7. Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
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