2型糖尿病和非糖尿病患者拔牙后牙槽窝局部菌血症的前瞻性研究。

Q3 Dentistry
Indian Journal of Dental Research Pub Date : 2025-04-01 Epub Date: 2025-08-04 DOI:10.4103/ijdr.ijdr_520_24
Amisha Nayak, Yogesh Kini, Ketaki Bhor, Varsha Yadav, Junaid Ahmed, Srikant Natrajan
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引用次数: 0

摘要

背景:拔牙会将细菌引入血液,导致短暂的菌血症。糖尿病人更容易受到影响,因为免疫功能受损,愈合延迟,感染清除减少。虽然系统性菌血症研究得很好,但来自牙槽窝的局部菌血症仍未得到充分研究。本研究比较糖尿病和非糖尿病患者拔牙后菌血症,以改善感染风险评估和预防护理。目的:1。比较糖尿病和非糖尿病患者的牙槽窝菌血症。2. 评估两组的菌血症患病率和严重程度。3. 评估糖尿病对拔牙后菌血症的影响。4. 鉴定主要细菌种类及其临床意义。5. 检查菌血症、血糖控制、愈合反应和感染风险之间的关系。材料与方法:选取年龄30 ~ 70岁、社会经济背景中低的患者60例,其中糖尿病患者30例,非糖尿病患者30例。糖尿病患者以男性为主,非糖尿病患者以女性为主。取取取后的窝血,在血琼脂上培养,37℃孵育24小时。细菌鉴定采用显微镜检查和确证性分析。结果:糖尿病患者链球菌(56.6%)、肠球菌(26.6%)、克雷伯氏菌(3.3%)、念珠菌(3.3%)的检出率高于非糖尿病患者,而肠球菌(40%)、链球菌(30%)、莫拉氏菌(16.6%)、大肠杆菌(3.3%)的检出率高于非糖尿病患者。葡萄球菌和肺炎球菌是糖尿病患者所特有的。结论:局部菌血症可能提示全身性健康风险。需要进一步的研究来建立临床相关性,完善治疗方案,改进早期干预策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Localized Bacteremia in Alveolar Sockets after Tooth Extraction in Type II Diabetic and Non-Diabetic Patients - A Prospective Study.

Background: Tooth extractions can introduce bacteria into the bloodstream, leading to transient bacteremia. Diabetic individuals are more susceptible due to impaired immunity, delayed healing, and reduced infection clearance. While systemic bacteremia is well-studied, localized bacteremia from the alveolar socket remains underexplored. This study compares post-extraction bacteremia in diabetic and non-diabetic patients to improve infection risk assessment and preventive care.

Objectives: 1. Compare alveolar socket bacteremia in diabetic and non-diabetic patients. 2. Assess bacteremia prevalence and severity in both groups. 3. Evaluate the impact of diabetes on post-extraction bacteremia. 4. Identify predominant bacterial species and their clinical relevance. 5. Examine associations between bacteremia, glycemic control, healing response, and infection risk.

Materials and methods: Sixty patients (30 diabetics, 30 non-diabetics) aged 30-70 from low-to-medium socioeconomic backgrounds were studied. Males predominated among diabetics, females among non-diabetics. Post-extraction socket blood was collected, cultured on blood agar, and incubated at 37°C for 24 hours. Bacterial identification was performed using microscopic examination and confirmatory assays.

Results: Statistical analysis ( p ≤ 0.05) showed diabetics had higher Streptococcus (56.6%), Enterococcus (26.6%), Klebsiella (3.3%), and Candida (3.3%), while non-diabetics had Enterococcus (40%), Streptococcus (30%), Moraxella (16.6%), and Escherichia coli (3.3%). Staphylococcus and Pneumococcus were exclusive to diabetics.

Conclusion: Localized bacteremia may indicate systemic health risks. Further research is needed to establish clinical correlations, refine treatment protocols, and improve early intervention strategies.

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来源期刊
Indian Journal of Dental Research
Indian Journal of Dental Research Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
80
审稿时长
38 weeks
期刊介绍: Indian Journal of Dental Research (IJDR) is the official publication of the Indian Society for Dental Research (ISDR), India section of the International Association for Dental Research (IADR), published quarterly. IJDR publishes scientific papers on well designed and controlled original research involving orodental sciences. Papers may also include reports on unusual and interesting case presentations and invited review papers on significant topics.
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