Nd:YAG激光后囊膜切开术后视网膜血管密度变化的光学相干断层扫描血管造影检测。

IF 1.5 4区 医学 Q3 OPHTHALMOLOGY
Serhat Ayla, Sevim Ayça Seyyar, Kıvanç Güngör
{"title":"Nd:YAG激光后囊膜切开术后视网膜血管密度变化的光学相干断层扫描血管造影检测。","authors":"Serhat Ayla, Sevim Ayça Seyyar, Kıvanç Güngör","doi":"10.1080/08164622.2025.2542325","DOIUrl":null,"url":null,"abstract":"<p><strong>Clinical relevance: </strong>Nd:YAG laser capsulotomy is a standard treatment for posterior capsule opacification. While effective, it may induce subclinical changes in retinal structure or perfusion. Optical coherence tomography angiography enables non-invasive visualisation of retinal microvasculature and is a valuable tool for monitoring potential vascular effects of intraocular laser procedures.</p><p><strong>Background: </strong>Posterior capsule opacification is the most common delayed complication following cataract surgery. Nd:YAG laser posterior capsulotomy is the standard treatment, but its effects on retinal microcirculation remain under-investigated. Optical coherence tomography angiography offers high-resolution vascular imaging but differentiating true vascular alterations from improved visualisation after media clearing presents a diagnostic challenge.</p><p><strong>Methods: </strong>This prospective study included 30 pseudophakic patients undergoing Nd:YAG capsulotomy for visually significant posterior capsule opacification. optical coherence tomography angiography imaging was performed at baseline, 1 hour, 1 week, and 1 month after treatment. The untreated pseudophakic fellow eyes of 25 patients served as internal controls. Vessel density measurements were obtained from the superficial capillary plexus (SCP-VD), deep capillary plexus (DCP-VD), and radial peripapillary capillaries. Intra-group changes were analysed with repeated measures ANOVA, and inter-eye comparisons were performed using independent samples t-tests.</p><p><strong>Results: </strong>SCP-VD showed significant increases in nasal and inferior parafoveal and perifoveal sectors at 1 week and 1 month (<i>p</i> < 0.05). DCP-VD also increased postoperatively, particularly in the foveal and superior perifoveal areas. Deep foveal vascular density at 1 month was significantly higher than in fellow eyes (<i>p</i> = 0.013). Peripapillary capillaries vascular density increased significantly over time (<i>p</i> = 0.035), though inter-eye differences were not significant.</p><p><strong>Conclusion: </strong>Optical coherence tomography angiography detects localised vascular changes following Nd:YAG capsulotomy. Incorporating fellow-eye controls strengthens interpretive accuracy by minimising the confounding effects of image quality improvement, supporting the clinical use of optical coherence tomography angiography in postoperative retinal assessment of pseudophakic patients.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-11"},"PeriodicalIF":1.5000,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Retinal vascular density changes detected by optical coherence tomography angiography following Nd:YAG laser posterior capsulotomy.\",\"authors\":\"Serhat Ayla, Sevim Ayça Seyyar, Kıvanç Güngör\",\"doi\":\"10.1080/08164622.2025.2542325\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Clinical relevance: </strong>Nd:YAG laser capsulotomy is a standard treatment for posterior capsule opacification. While effective, it may induce subclinical changes in retinal structure or perfusion. Optical coherence tomography angiography enables non-invasive visualisation of retinal microvasculature and is a valuable tool for monitoring potential vascular effects of intraocular laser procedures.</p><p><strong>Background: </strong>Posterior capsule opacification is the most common delayed complication following cataract surgery. Nd:YAG laser posterior capsulotomy is the standard treatment, but its effects on retinal microcirculation remain under-investigated. Optical coherence tomography angiography offers high-resolution vascular imaging but differentiating true vascular alterations from improved visualisation after media clearing presents a diagnostic challenge.</p><p><strong>Methods: </strong>This prospective study included 30 pseudophakic patients undergoing Nd:YAG capsulotomy for visually significant posterior capsule opacification. optical coherence tomography angiography imaging was performed at baseline, 1 hour, 1 week, and 1 month after treatment. The untreated pseudophakic fellow eyes of 25 patients served as internal controls. Vessel density measurements were obtained from the superficial capillary plexus (SCP-VD), deep capillary plexus (DCP-VD), and radial peripapillary capillaries. Intra-group changes were analysed with repeated measures ANOVA, and inter-eye comparisons were performed using independent samples t-tests.</p><p><strong>Results: </strong>SCP-VD showed significant increases in nasal and inferior parafoveal and perifoveal sectors at 1 week and 1 month (<i>p</i> < 0.05). DCP-VD also increased postoperatively, particularly in the foveal and superior perifoveal areas. Deep foveal vascular density at 1 month was significantly higher than in fellow eyes (<i>p</i> = 0.013). Peripapillary capillaries vascular density increased significantly over time (<i>p</i> = 0.035), though inter-eye differences were not significant.</p><p><strong>Conclusion: </strong>Optical coherence tomography angiography detects localised vascular changes following Nd:YAG capsulotomy. Incorporating fellow-eye controls strengthens interpretive accuracy by minimising the confounding effects of image quality improvement, supporting the clinical use of optical coherence tomography angiography in postoperative retinal assessment of pseudophakic patients.</p>\",\"PeriodicalId\":10214,\"journal\":{\"name\":\"Clinical and Experimental Optometry\",\"volume\":\" \",\"pages\":\"1-11\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-08-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Optometry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/08164622.2025.2542325\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Optometry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/08164622.2025.2542325","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

临床意义:Nd:YAG激光囊切开术是治疗后囊膜混浊的标准方法。虽然有效,但可能引起视网膜结构或灌注的亚临床改变。光学相干断层血管造影能够实现视网膜微血管的无创可视化,是监测眼内激光手术潜在血管效应的宝贵工具。背景:后囊膜混浊是白内障手术后最常见的延迟性并发症。Nd:YAG激光后囊膜切开术是标准的治疗方法,但其对视网膜微循环的影响仍有待研究。光学相干断层血管造影提供了高分辨率的血管成像,但在介质清除后区分真正的血管改变和改善的视觉效果是诊断上的挑战。方法:本前瞻性研究包括30例假性白内障患者,他们接受Nd:YAG囊切开术治疗视觉上明显的后囊膜混浊。在基线、治疗后1小时、1周和1个月进行光学相干断层扫描血管造影成像。25例未治疗的假性近视患者作为内部对照。血管密度测量来自浅毛细血管丛(SCP-VD)、深毛细血管丛(DCP-VD)和径向乳头周围毛细血管。组内变化采用重复测量方差分析分析,眼间比较采用独立样本t检验。结果:SCP-VD在第1周和第1个月时显示出鼻、下凹旁和凹周区显著增加(p p = 0.013)。随着时间的推移,乳突周围毛细血管密度显著增加(p = 0.035),但眼间差异不显著。结论:光学相干断层扫描血管造影可检测Nd:YAG囊切开术后的局部血管改变。结合同眼对照,通过最大限度地减少图像质量改善的混淆效应,增强了解释的准确性,支持光学相干断层血管造影在假性晶状体患者术后视网膜评估中的临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retinal vascular density changes detected by optical coherence tomography angiography following Nd:YAG laser posterior capsulotomy.

Clinical relevance: Nd:YAG laser capsulotomy is a standard treatment for posterior capsule opacification. While effective, it may induce subclinical changes in retinal structure or perfusion. Optical coherence tomography angiography enables non-invasive visualisation of retinal microvasculature and is a valuable tool for monitoring potential vascular effects of intraocular laser procedures.

Background: Posterior capsule opacification is the most common delayed complication following cataract surgery. Nd:YAG laser posterior capsulotomy is the standard treatment, but its effects on retinal microcirculation remain under-investigated. Optical coherence tomography angiography offers high-resolution vascular imaging but differentiating true vascular alterations from improved visualisation after media clearing presents a diagnostic challenge.

Methods: This prospective study included 30 pseudophakic patients undergoing Nd:YAG capsulotomy for visually significant posterior capsule opacification. optical coherence tomography angiography imaging was performed at baseline, 1 hour, 1 week, and 1 month after treatment. The untreated pseudophakic fellow eyes of 25 patients served as internal controls. Vessel density measurements were obtained from the superficial capillary plexus (SCP-VD), deep capillary plexus (DCP-VD), and radial peripapillary capillaries. Intra-group changes were analysed with repeated measures ANOVA, and inter-eye comparisons were performed using independent samples t-tests.

Results: SCP-VD showed significant increases in nasal and inferior parafoveal and perifoveal sectors at 1 week and 1 month (p < 0.05). DCP-VD also increased postoperatively, particularly in the foveal and superior perifoveal areas. Deep foveal vascular density at 1 month was significantly higher than in fellow eyes (p = 0.013). Peripapillary capillaries vascular density increased significantly over time (p = 0.035), though inter-eye differences were not significant.

Conclusion: Optical coherence tomography angiography detects localised vascular changes following Nd:YAG capsulotomy. Incorporating fellow-eye controls strengthens interpretive accuracy by minimising the confounding effects of image quality improvement, supporting the clinical use of optical coherence tomography angiography in postoperative retinal assessment of pseudophakic patients.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
4.10
自引率
5.30%
发文量
132
审稿时长
6-12 weeks
期刊介绍: Clinical and Experimental Optometry is a peer reviewed journal listed by ISI and abstracted by PubMed, Web of Science, Scopus, Science Citation Index and Current Contents. It publishes original research papers and reviews in clinical optometry and vision science. Debate and discussion of controversial scientific and clinical issues is encouraged and letters to the Editor and short communications expressing points of view on matters within the Journal''s areas of interest are welcome. The Journal is published six times annually.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信