Shriniwas P. Patil, Rajesh Y. Chaudhari, Mahesh S. Nemade
{"title":"Cajanus cajan豆荚协助绿色合成纳米银及其细胞毒性评价。","authors":"Shriniwas P. Patil, Rajesh Y. Chaudhari, Mahesh S. Nemade","doi":"10.1007/s00114-025-02006-x","DOIUrl":null,"url":null,"abstract":"<div><p>Nowadays, the fabrication of silver nanoparticles (Ag NPs) is receiving considerable attention due to their wide range of applications in various domains. The green approach to synthesizing Ag NPs is cost-effective and ecologically safe, as it does not involve any sophisticated instruments or hazardous chemicals. <i>Cajanus cajan</i> (CC, Pigeon pea) is a plant belonging to the family Fabaceae. So far, only pigeon pea leaves and seeds have been used in the synthesis of NPs. After the removal of edible seeds, pods are fed to cattle as fodder. The pods contain different flavonoids, iridoids, and other miscellaneous compounds. The present research focuses on the use of <i>C. cajan</i> pods in the fabrication of Ag NPs and the evaluation of their cytotoxicity against normal and breast cancer cells. On characterization, Ag NPs were found to be oval in shape, crystalline in nature, and capped with phytochemicals present in CC. The results of the MTT assay revealed that Ag NPs are cytotoxic to breast cancer cells. It can be concluded that phytochemicals present in<i> C</i>. <i>cajan</i> pods reduced the precursor into Ag NPs, which were significantly biologically active.\n</p></div>","PeriodicalId":794,"journal":{"name":"The Science of Nature","volume":"112 5","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cajanus cajan pods assisted green synthesis of silver nanoparticles and assessment of their cytotoxicity\",\"authors\":\"Shriniwas P. Patil, Rajesh Y. Chaudhari, Mahesh S. Nemade\",\"doi\":\"10.1007/s00114-025-02006-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Nowadays, the fabrication of silver nanoparticles (Ag NPs) is receiving considerable attention due to their wide range of applications in various domains. The green approach to synthesizing Ag NPs is cost-effective and ecologically safe, as it does not involve any sophisticated instruments or hazardous chemicals. <i>Cajanus cajan</i> (CC, Pigeon pea) is a plant belonging to the family Fabaceae. So far, only pigeon pea leaves and seeds have been used in the synthesis of NPs. After the removal of edible seeds, pods are fed to cattle as fodder. The pods contain different flavonoids, iridoids, and other miscellaneous compounds. The present research focuses on the use of <i>C. cajan</i> pods in the fabrication of Ag NPs and the evaluation of their cytotoxicity against normal and breast cancer cells. On characterization, Ag NPs were found to be oval in shape, crystalline in nature, and capped with phytochemicals present in CC. The results of the MTT assay revealed that Ag NPs are cytotoxic to breast cancer cells. It can be concluded that phytochemicals present in<i> C</i>. <i>cajan</i> pods reduced the precursor into Ag NPs, which were significantly biologically active.\\n</p></div>\",\"PeriodicalId\":794,\"journal\":{\"name\":\"The Science of Nature\",\"volume\":\"112 5\",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-08-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Science of Nature\",\"FirstCategoryId\":\"6\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00114-025-02006-x\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MULTIDISCIPLINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Science of Nature","FirstCategoryId":"6","ListUrlMain":"https://link.springer.com/article/10.1007/s00114-025-02006-x","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
Cajanus cajan pods assisted green synthesis of silver nanoparticles and assessment of their cytotoxicity
Nowadays, the fabrication of silver nanoparticles (Ag NPs) is receiving considerable attention due to their wide range of applications in various domains. The green approach to synthesizing Ag NPs is cost-effective and ecologically safe, as it does not involve any sophisticated instruments or hazardous chemicals. Cajanus cajan (CC, Pigeon pea) is a plant belonging to the family Fabaceae. So far, only pigeon pea leaves and seeds have been used in the synthesis of NPs. After the removal of edible seeds, pods are fed to cattle as fodder. The pods contain different flavonoids, iridoids, and other miscellaneous compounds. The present research focuses on the use of C. cajan pods in the fabrication of Ag NPs and the evaluation of their cytotoxicity against normal and breast cancer cells. On characterization, Ag NPs were found to be oval in shape, crystalline in nature, and capped with phytochemicals present in CC. The results of the MTT assay revealed that Ag NPs are cytotoxic to breast cancer cells. It can be concluded that phytochemicals present in C. cajan pods reduced the precursor into Ag NPs, which were significantly biologically active.
期刊介绍:
The Science of Nature - Naturwissenschaften - is Springer''s flagship multidisciplinary science journal. The journal is dedicated to the fast publication and global dissemination of high-quality research and invites papers, which are of interest to the broader community in the biological sciences. Contributions from the chemical, geological, and physical sciences are welcome if contributing to questions of general biological significance. Particularly welcomed are contributions that bridge between traditionally isolated areas and attempt to increase the conceptual understanding of systems and processes that demand an interdisciplinary approach.