{"title":"更正“高效制备人间充质干细胞细胞外囊泡的微珠封装策略”","authors":"","doi":"10.1002/jev2.70144","DOIUrl":null,"url":null,"abstract":"<p>Tan, J., Y. Hu,L. Zheng, et al. 2025. “Microbead Encapsulation Strategy for Efficient Production of Extracellular Vesicles Derived From Human Mesenchymal Stem Cells.” <i>Journal of Extracellular Vesicles</i> 14: e70053. https://doi.org/10.1002/jev2.70053</p><p>In the originally published article, author Jiayi Tan was left off the author list. The correct author list appears below. This has been updated in the online version of the article.</p><p>Jiayi Tan,<sup>1</sup> Yunxia Hu,<sup>2,3,4</sup> Lijuan Zheng,<sup>2,3,4</sup> Zheng Zheng,<sup>5</sup> Mali Fu,<sup>5</sup> Haiying Peng,<sup>6</sup> Shaohua Ma<sup>2,3,4</sup></p><p><sup>1</sup>Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, Shenzhen, China</p><p><sup>2</sup>Institute of Biopharmaceutical and Health Engineering (iBHE), Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, Shenzhen, China</p><p><sup>3</sup>Key Lab of Industrial Biocatalysis, Ministry of Education, Shenzhen, China</p><p><sup>4</sup>Key Lab of Active Proteins and Peptides Green Biomanufacturing of Guangdong Higher Education Institutes, Tsinghua Shenzhen International Graduate School, Shenzhen, China</p><p><sup>5</sup>Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China</p><p><sup>6</sup>General Hospital of the Southern Theater Command of the Chinese People's Liberation Army, Guangzhou, China</p><p>Additionally, Figure 1d in this paper partially duplicates Figure 3a from Cao et al. 2022. The authors have replaced the duplicated live/dead staining image in Figure 1d with data from another batch of repeat experiments (see below).</p><p>The caption for Figure 2, which appears below, has been revised because Figure 2c, which presents the size distribution and concentration of hMSC-EVs as measured by NTA, also appeared in Appendix S25 of the publication by Cao et al., 2022.</p><p>Figure 2 Characterisation and comparison of hMSC-EVs derived from microbeads and 2D groups. (a) The experimental workflow of EV collection and isolation. (b) Representative TEM image of hMSC-EVs. Scale bar, 200 nm. (c) Size distribution and concentration of hMSC-EVs measured by NTA. Data in this panel were replicated from Appendix S25 of Cao et al., 2022. (d) Comparison of size distribution and concentration results measured by NTA of hMSC-EVs. (e–f) Average diameter and normalised particle concentration of hMSC-EVs based on NTA results. (g, h) Protein and RNA content in hMSC-EVs. (i) Western blot analysis of marker proteins (Hsp70, TSG101, CD63) in hMSC-EVs. <sup>*</sup><i>p</i> < 0.05; <sup>**</sup><i>p</i> < 0.01; <sup>***</sup><i>p</i> < 0.001; <sup>****</sup><i>p</i> < 0.0001.</p><p>We apologize for these error.</p>","PeriodicalId":15811,"journal":{"name":"Journal of Extracellular Vesicles","volume":"14 8","pages":""},"PeriodicalIF":14.5000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jev2.70144","citationCount":"0","resultStr":"{\"title\":\"Correction to \\\"Microbead Encapsulation Strategy for Efficient Production of Extracellular Vesicles Derived From Human Mesenchymal Stem Cells\\\"\",\"authors\":\"\",\"doi\":\"10.1002/jev2.70144\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Tan, J., Y. Hu,L. Zheng, et al. 2025. “Microbead Encapsulation Strategy for Efficient Production of Extracellular Vesicles Derived From Human Mesenchymal Stem Cells.” <i>Journal of Extracellular Vesicles</i> 14: e70053. https://doi.org/10.1002/jev2.70053</p><p>In the originally published article, author Jiayi Tan was left off the author list. The correct author list appears below. This has been updated in the online version of the article.</p><p>Jiayi Tan,<sup>1</sup> Yunxia Hu,<sup>2,3,4</sup> Lijuan Zheng,<sup>2,3,4</sup> Zheng Zheng,<sup>5</sup> Mali Fu,<sup>5</sup> Haiying Peng,<sup>6</sup> Shaohua Ma<sup>2,3,4</sup></p><p><sup>1</sup>Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, Shenzhen, China</p><p><sup>2</sup>Institute of Biopharmaceutical and Health Engineering (iBHE), Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, Shenzhen, China</p><p><sup>3</sup>Key Lab of Industrial Biocatalysis, Ministry of Education, Shenzhen, China</p><p><sup>4</sup>Key Lab of Active Proteins and Peptides Green Biomanufacturing of Guangdong Higher Education Institutes, Tsinghua Shenzhen International Graduate School, Shenzhen, China</p><p><sup>5</sup>Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China</p><p><sup>6</sup>General Hospital of the Southern Theater Command of the Chinese People's Liberation Army, Guangzhou, China</p><p>Additionally, Figure 1d in this paper partially duplicates Figure 3a from Cao et al. 2022. The authors have replaced the duplicated live/dead staining image in Figure 1d with data from another batch of repeat experiments (see below).</p><p>The caption for Figure 2, which appears below, has been revised because Figure 2c, which presents the size distribution and concentration of hMSC-EVs as measured by NTA, also appeared in Appendix S25 of the publication by Cao et al., 2022.</p><p>Figure 2 Characterisation and comparison of hMSC-EVs derived from microbeads and 2D groups. (a) The experimental workflow of EV collection and isolation. (b) Representative TEM image of hMSC-EVs. Scale bar, 200 nm. (c) Size distribution and concentration of hMSC-EVs measured by NTA. Data in this panel were replicated from Appendix S25 of Cao et al., 2022. (d) Comparison of size distribution and concentration results measured by NTA of hMSC-EVs. (e–f) Average diameter and normalised particle concentration of hMSC-EVs based on NTA results. (g, h) Protein and RNA content in hMSC-EVs. (i) Western blot analysis of marker proteins (Hsp70, TSG101, CD63) in hMSC-EVs. <sup>*</sup><i>p</i> < 0.05; <sup>**</sup><i>p</i> < 0.01; <sup>***</sup><i>p</i> < 0.001; <sup>****</sup><i>p</i> < 0.0001.</p><p>We apologize for these error.</p>\",\"PeriodicalId\":15811,\"journal\":{\"name\":\"Journal of Extracellular Vesicles\",\"volume\":\"14 8\",\"pages\":\"\"},\"PeriodicalIF\":14.5000,\"publicationDate\":\"2025-08-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jev2.70144\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Extracellular Vesicles\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev2.70144\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Extracellular Vesicles","FirstCategoryId":"3","ListUrlMain":"https://isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev2.70144","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
谭杰，胡玉玲，胡丽娟。郑等。2025。人间充质干细胞细胞外囊泡高效生产的微珠封装策略细胞外囊泡学报（英文版）14(6):744 - 744。https://doi.org/10.1002/jev2.70053In最初发表的文章，作者谭嘉怡被排除在作者名单之外。正确的作者列表如下所示。这已在文章的在线版本中更新。谭佳怡，1胡云霞，2,3,4郑丽娟，2,3,4郑铮，5傅玛丽，5彭海英，6马少华2,3,41中国深圳清华大学深圳国际研究生院2中国深圳清华大学深圳国际研究生院生物制药与健康工程研究所3工业生物催化教育部重点实验室，深圳，4中国广东省高等学校活性蛋白与多肽绿色生物制造重点实验室，清华深圳国际研究生院，中国深圳5中国深圳妇幼保健院，中国深圳6中国人民解放军南方战区总医院，中国广州另外，本文中的图1d部分重复了Cao等人的图3a。作者将图1d中重复的活/死染色图像替换为另一批重复实验的数据（见下文）。下图2的标题经过了修改，因为图2c显示了NTA测量的hmsc - ev的大小分布和浓度，也出现在Cao et al.， 2022出版的附录S25中。图2来自微珠和2D基团的hmsc - ev的表征和比较。(a) EV采集和分离的实验流程。(b) hmsc - ev的代表性TEM图像。比例尺，200nm。(c) NTA测定的hmsc - ev的大小分布和浓度。本小组的数据复制自Cao等人，2022年的附录S25。(d) hmsc - ev的粒径分布和NTA测定的浓度结果比较。（e-f）基于NTA结果的hmsc - ev的平均直径和归一化颗粒浓度。（g, h） hmsc - ev蛋白和RNA含量。(i) hmsc - ev标记蛋白（Hsp70、TSG101、CD63）的Western blot分析。* p & lt;0.05;* * p & lt;0.01;* * * p & lt;0.001;* * * * p & lt;0.0001.我们为这些错误道歉。
Correction to "Microbead Encapsulation Strategy for Efficient Production of Extracellular Vesicles Derived From Human Mesenchymal Stem Cells"
Tan, J., Y. Hu,L. Zheng, et al. 2025. “Microbead Encapsulation Strategy for Efficient Production of Extracellular Vesicles Derived From Human Mesenchymal Stem Cells.” Journal of Extracellular Vesicles 14: e70053. https://doi.org/10.1002/jev2.70053
In the originally published article, author Jiayi Tan was left off the author list. The correct author list appears below. This has been updated in the online version of the article.
1Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, Shenzhen, China
2Institute of Biopharmaceutical and Health Engineering (iBHE), Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, Shenzhen, China
3Key Lab of Industrial Biocatalysis, Ministry of Education, Shenzhen, China
4Key Lab of Active Proteins and Peptides Green Biomanufacturing of Guangdong Higher Education Institutes, Tsinghua Shenzhen International Graduate School, Shenzhen, China
5Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China
6General Hospital of the Southern Theater Command of the Chinese People's Liberation Army, Guangzhou, China
Additionally, Figure 1d in this paper partially duplicates Figure 3a from Cao et al. 2022. The authors have replaced the duplicated live/dead staining image in Figure 1d with data from another batch of repeat experiments (see below).
The caption for Figure 2, which appears below, has been revised because Figure 2c, which presents the size distribution and concentration of hMSC-EVs as measured by NTA, also appeared in Appendix S25 of the publication by Cao et al., 2022.
Figure 2 Characterisation and comparison of hMSC-EVs derived from microbeads and 2D groups. (a) The experimental workflow of EV collection and isolation. (b) Representative TEM image of hMSC-EVs. Scale bar, 200 nm. (c) Size distribution and concentration of hMSC-EVs measured by NTA. Data in this panel were replicated from Appendix S25 of Cao et al., 2022. (d) Comparison of size distribution and concentration results measured by NTA of hMSC-EVs. (e–f) Average diameter and normalised particle concentration of hMSC-EVs based on NTA results. (g, h) Protein and RNA content in hMSC-EVs. (i) Western blot analysis of marker proteins (Hsp70, TSG101, CD63) in hMSC-EVs. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.
期刊介绍：
The Journal of Extracellular Vesicles is an open access research publication that focuses on extracellular vesicles, including microvesicles, exosomes, ectosomes, and apoptotic bodies. It serves as the official journal of the International Society for Extracellular Vesicles and aims to facilitate the exchange of data, ideas, and information pertaining to the chemistry, biology, and applications of extracellular vesicles. The journal covers various aspects such as the cellular and molecular mechanisms of extracellular vesicles biogenesis, technological advancements in their isolation, quantification, and characterization, the role and function of extracellular vesicles in biology, stem cell-derived extracellular vesicles and their biology, as well as the application of extracellular vesicles for pharmacological, immunological, or genetic therapies.
The Journal of Extracellular Vesicles is widely recognized and indexed by numerous services, including Biological Abstracts, BIOSIS Previews, Chemical Abstracts Service (CAS), Current Contents/Life Sciences, Directory of Open Access Journals (DOAJ), Journal Citation Reports/Science Edition, Google Scholar, ProQuest Natural Science Collection, ProQuest SciTech Collection, SciTech Premium Collection, PubMed Central/PubMed, Science Citation Index Expanded, ScienceOpen, and Scopus.
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