在巴西的亚马逊河流域，一种弓形虫中毒后胎盘早剥和早产

IF 2.4 4区医学 Q2 PHARMACOLOGY & PHARMACY

Toxicon Pub Date : 2025-08-05 DOI:10.1016/j.toxicon.2025.108514

Jacqueline de Almeida Gonçalves Sachett , Handerson da Silva Pereira , Débora Nery Oliveira , Thaís Pinto Nascimento , Maria Cristina Martins de Oliveira , Joseir Saturnino Cristino , Felipe Queiroz Araújo , Erica Silva Carvalho , Wuelton Marcelo Monteiro

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引用次数: 0

摘要

孕妇中毒可导致显著不良的孕产妇和新生儿结局。本病例报告了一位12岁的怀孕少女，她经历了B. atrox中毒，并发展为胎盘早剥和早产。患者出现全身并发症，包括凝血功能障碍和严重贫血，需要抗蛇毒血清治疗和分娩后输血支持。这名早产儿和低出生体重新生儿需要重症监护支持。本报告强调了河流人口对蛇咬伤的高度脆弱性，特别是怀孕的青少年，并强调需要制定预防方案和改善卫生基础设施，以尽量减少相关并发症。它还强调了充分的住院随访的重要性，因为短期住院可能不足以确保产妇完全康复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Placental abruption and premature birth following a Bothrops atrox envenomation in the Brazilian Amazon

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Placental abruption and premature birth following a Bothrops atrox envenomation in the Brazilian Amazon

Bothrops atrox envenomation in pregnant women can result in significant adverse maternal and neonatal outcomes. This case reports of a 12-year-old pregnant adolescent who experienced B. atrox envenomation who developed placental abruption and premature birth. The patient presented systemic complications, including coagulation disorders and severe anemia, requiring treatment with antivenom and transfusion support after delivery. The newborn, premature and with low birth weight, needed intensive care support. This report highlights the high vulnerability of riverine populations to snakebite envenomation, especially pregnant adolescents, and emphasizes the need for prevention programs and improvements in health infrastructure to minimize the associated complications. It also underscores the importance of adequate inpatient follow-up, as short hospital stays may be insufficient to ensure full maternal recovery.

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来源期刊

Toxicon 医学-毒理学

CiteScore

4.80

自引率

10.70%

发文量

358

审稿时长

68 days

期刊介绍： Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee. Toxicon''s "aims and scope" are to publish: -articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms -papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins -molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins -clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained. -material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems. -articles on the translational application of toxins, for example as drugs and insecticides -epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged. -articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon. -review articles on problems related to toxinology. To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.