Dongqi You , Lining Lin , Minyi Dong , Yunhong Wu , Yijie Hu , Xinyue Hu , Yangjie Shao , Yuan Xie , Menghan Xu , Guancong Chen , Rong Lan , Haiying Ma , Yunting Zhou , Huiming Wang , Binjie Jin , Mengfei Yu
{"title":"生物医学用途的形状记忆聚合物的最新进展:桥接宏观和微观尺度效应","authors":"Dongqi You , Lining Lin , Minyi Dong , Yunhong Wu , Yijie Hu , Xinyue Hu , Yangjie Shao , Yuan Xie , Menghan Xu , Guancong Chen , Rong Lan , Haiying Ma , Yunting Zhou , Huiming Wang , Binjie Jin , Mengfei Yu","doi":"10.1016/j.smaim.2025.06.001","DOIUrl":null,"url":null,"abstract":"<div><div>Shape memory polymers (SMPs) are a class of materials capable of undergoing deformation in response to external stimuli, and their unique shape-changing properties offer vast potential for applications in the biomedical field. Based on the dimensionality of the shape memory effect (SME), deformation can be categorized into macroscopic and microscopic levels. Macroscopic deformation enables SMPs to perform functions such as adaptation, filling, and support through overall structural changes. On the other hand, microscopic deformation involves dynamic modulation of the surface morphology of micro- and nanoscale scaffolds, influencing cell morphology and further regulating cell behavior and fate. Whether at the macroscopic or microscopic level, SME significantly enhances the performance of SMPs as tissue scaffolds or medical devices. This review summarizes the progress of SMP applications in the biomedical field, focusing on SME at different dimensional levels, and provides insights into future development directions.</div></div>","PeriodicalId":22019,"journal":{"name":"Smart Materials in Medicine","volume":"6 2","pages":"Pages 240-269"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Recent advances in shape memory polymers for biomedical applications: Bridging macro- and micro-scale effects\",\"authors\":\"Dongqi You , Lining Lin , Minyi Dong , Yunhong Wu , Yijie Hu , Xinyue Hu , Yangjie Shao , Yuan Xie , Menghan Xu , Guancong Chen , Rong Lan , Haiying Ma , Yunting Zhou , Huiming Wang , Binjie Jin , Mengfei Yu\",\"doi\":\"10.1016/j.smaim.2025.06.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Shape memory polymers (SMPs) are a class of materials capable of undergoing deformation in response to external stimuli, and their unique shape-changing properties offer vast potential for applications in the biomedical field. Based on the dimensionality of the shape memory effect (SME), deformation can be categorized into macroscopic and microscopic levels. Macroscopic deformation enables SMPs to perform functions such as adaptation, filling, and support through overall structural changes. On the other hand, microscopic deformation involves dynamic modulation of the surface morphology of micro- and nanoscale scaffolds, influencing cell morphology and further regulating cell behavior and fate. Whether at the macroscopic or microscopic level, SME significantly enhances the performance of SMPs as tissue scaffolds or medical devices. This review summarizes the progress of SMP applications in the biomedical field, focusing on SME at different dimensional levels, and provides insights into future development directions.</div></div>\",\"PeriodicalId\":22019,\"journal\":{\"name\":\"Smart Materials in Medicine\",\"volume\":\"6 2\",\"pages\":\"Pages 240-269\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Smart Materials in Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S259018342500016X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Engineering\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Smart Materials in Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S259018342500016X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Engineering","Score":null,"Total":0}
Recent advances in shape memory polymers for biomedical applications: Bridging macro- and micro-scale effects
Shape memory polymers (SMPs) are a class of materials capable of undergoing deformation in response to external stimuli, and their unique shape-changing properties offer vast potential for applications in the biomedical field. Based on the dimensionality of the shape memory effect (SME), deformation can be categorized into macroscopic and microscopic levels. Macroscopic deformation enables SMPs to perform functions such as adaptation, filling, and support through overall structural changes. On the other hand, microscopic deformation involves dynamic modulation of the surface morphology of micro- and nanoscale scaffolds, influencing cell morphology and further regulating cell behavior and fate. Whether at the macroscopic or microscopic level, SME significantly enhances the performance of SMPs as tissue scaffolds or medical devices. This review summarizes the progress of SMP applications in the biomedical field, focusing on SME at different dimensional levels, and provides insights into future development directions.