Bo Xu, Yurou Xu, Yu Wang, Rong Hua, Qiwei Shen, Wen Zhang, Xing Liu, Qiyuan Yao
{"title":"619例中国患者腹腔镜袖胃切除术后贫血与性别、BMI、术前FIB-4指数和补铁相关：一项回顾性队列研究。","authors":"Bo Xu, Yurou Xu, Yu Wang, Rong Hua, Qiwei Shen, Wen Zhang, Xing Liu, Qiyuan Yao","doi":"10.1016/j.soard.2025.06.010","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Laparoscopic sleeve gastrectomy (LSG) has become a common bariatric procedure in China, and the long-term risk of postoperative anemia remains to be estimated. This study aimed to investigate the incidence and risk factors of anemia at different times after LSG in Chinese population.</p><p><strong>Objectives: </strong>To investigate the incidence of postoperative anemia and its risk factors in a cohort of Chinese patients with obesity undergoing LSG.</p><p><strong>Setting: </strong>Huashan Hospital, Fudan University, Shanghai, China.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted on 619 patients who underwent LSG at a tertiary hospital between 2012 and 2022. The incidence of anemia at different postoperative stages was reported, and risk factors were explored using multivariable logistic regression.</p><p><strong>Results: </strong>Among the 619 patients, 567, 436, and 189 participated in 0∼3, 3+∼12, and 12+∼60 months follow-up visits, respectively. The cumulative incidence of anemia for each period were 9.3%, 6.6%, and 9.1% for males, lower than those of 13.5%, 20.6%, and 39.2% for females. During the first 3 months of follow-up, preoperative iron deficiency was associated with a higher incidence of postoperative anemia (odds ratio [OR]: 3.67, 95% confidence interval [CI]: 1.11-12.16), and iron supplementation was associated with a lower risk of anemia among all patients (.46, .27-.77) and female patients (.49, .27-.87). In the period of 3+ - 12 months, females with advanced FIB-4 level (≥1.45, an index for liver fibrosis) had a higher incidence of anemia (5.72, 1.24-26.49). Among males, higher preoperative body mass index (BMI) was associated with a lower risk (.79, .64-.98), while weight loss was positively associated with anemia (1.26, 1.06-1.48).</p><p><strong>Conclusion: </strong>Postoperative anemia was frequent in Chinese patients undergoing LSG and was associated with female gender, lower BMI, advanced preoperative FIB-4 level, and a lack of iron supplementation after surgery.</p>","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sex, BMI, preoperative FIB-4 index, and iron supplementation were associated with postoperative anemia after laparoscopic sleeve gastrectomy among 619 Chinese patients: a retrospective cohort study.\",\"authors\":\"Bo Xu, Yurou Xu, Yu Wang, Rong Hua, Qiwei Shen, Wen Zhang, Xing Liu, Qiyuan Yao\",\"doi\":\"10.1016/j.soard.2025.06.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Laparoscopic sleeve gastrectomy (LSG) has become a common bariatric procedure in China, and the long-term risk of postoperative anemia remains to be estimated. This study aimed to investigate the incidence and risk factors of anemia at different times after LSG in Chinese population.</p><p><strong>Objectives: </strong>To investigate the incidence of postoperative anemia and its risk factors in a cohort of Chinese patients with obesity undergoing LSG.</p><p><strong>Setting: </strong>Huashan Hospital, Fudan University, Shanghai, China.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted on 619 patients who underwent LSG at a tertiary hospital between 2012 and 2022. The incidence of anemia at different postoperative stages was reported, and risk factors were explored using multivariable logistic regression.</p><p><strong>Results: </strong>Among the 619 patients, 567, 436, and 189 participated in 0∼3, 3+∼12, and 12+∼60 months follow-up visits, respectively. The cumulative incidence of anemia for each period were 9.3%, 6.6%, and 9.1% for males, lower than those of 13.5%, 20.6%, and 39.2% for females. During the first 3 months of follow-up, preoperative iron deficiency was associated with a higher incidence of postoperative anemia (odds ratio [OR]: 3.67, 95% confidence interval [CI]: 1.11-12.16), and iron supplementation was associated with a lower risk of anemia among all patients (.46, .27-.77) and female patients (.49, .27-.87). In the period of 3+ - 12 months, females with advanced FIB-4 level (≥1.45, an index for liver fibrosis) had a higher incidence of anemia (5.72, 1.24-26.49). Among males, higher preoperative body mass index (BMI) was associated with a lower risk (.79, .64-.98), while weight loss was positively associated with anemia (1.26, 1.06-1.48).</p><p><strong>Conclusion: </strong>Postoperative anemia was frequent in Chinese patients undergoing LSG and was associated with female gender, lower BMI, advanced preoperative FIB-4 level, and a lack of iron supplementation after surgery.</p>\",\"PeriodicalId\":94216,\"journal\":{\"name\":\"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.soard.2025.06.010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.soard.2025.06.010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Sex, BMI, preoperative FIB-4 index, and iron supplementation were associated with postoperative anemia after laparoscopic sleeve gastrectomy among 619 Chinese patients: a retrospective cohort study.
Introduction: Laparoscopic sleeve gastrectomy (LSG) has become a common bariatric procedure in China, and the long-term risk of postoperative anemia remains to be estimated. This study aimed to investigate the incidence and risk factors of anemia at different times after LSG in Chinese population.
Objectives: To investigate the incidence of postoperative anemia and its risk factors in a cohort of Chinese patients with obesity undergoing LSG.
Methods: A retrospective cohort study was conducted on 619 patients who underwent LSG at a tertiary hospital between 2012 and 2022. The incidence of anemia at different postoperative stages was reported, and risk factors were explored using multivariable logistic regression.
Results: Among the 619 patients, 567, 436, and 189 participated in 0∼3, 3+∼12, and 12+∼60 months follow-up visits, respectively. The cumulative incidence of anemia for each period were 9.3%, 6.6%, and 9.1% for males, lower than those of 13.5%, 20.6%, and 39.2% for females. During the first 3 months of follow-up, preoperative iron deficiency was associated with a higher incidence of postoperative anemia (odds ratio [OR]: 3.67, 95% confidence interval [CI]: 1.11-12.16), and iron supplementation was associated with a lower risk of anemia among all patients (.46, .27-.77) and female patients (.49, .27-.87). In the period of 3+ - 12 months, females with advanced FIB-4 level (≥1.45, an index for liver fibrosis) had a higher incidence of anemia (5.72, 1.24-26.49). Among males, higher preoperative body mass index (BMI) was associated with a lower risk (.79, .64-.98), while weight loss was positively associated with anemia (1.26, 1.06-1.48).
Conclusion: Postoperative anemia was frequent in Chinese patients undergoing LSG and was associated with female gender, lower BMI, advanced preoperative FIB-4 level, and a lack of iron supplementation after surgery.
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