Vinurajkumar S, Yamuna Devi K, Manikandan K, Sathish S
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Assessment of Gamma Band Power of Electroencephalogram in Alzheimer's disease.
Gamma transcranial alternating current stimulation (Gamma-tACS) is used for treating Alzheimer's disease (AD). The changes in the Gamma band power (GBP) of Electroencephalogram (EEG) manifested by AD can justify the reliability of enhancing the GBP via the Gamma-tACS. The EEG is the electric potential originating from the neural activity of the human brain. Our objective is to statistically investigate how far the AD patients differ from the healthy subjects in terms of GBP of resting-state EEG at the frontal electrodes. The dataset contains EEG recordings from 65 participants comprising 36 AD patients with an age of 66.39 ± 7.89 and 29 healthy subjects with an age of 67.90 ± 5.40. As a major finding, the Wilcoxon rank-sum test reveals that the difference in GBP of AD patients and healthy subjects is not significant at frontal polar 1 (FP1) (p = 0.81), FP2 (p = 0.48), frontal 3 (F3) (p = 0.77), F7 (p = 0.76), frontal zone (Fz) (p = 0.65), F4 (p = 0.91), and F8 (p = 0.42).
期刊介绍：
pplied Neuropsychology-Adult publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in adults. Full-length articles and brief communications are included. Case studies of adult patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.
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