猫的纯红细胞发育不全和无核细胞血小板减少症。

IF 1.1 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Veterinary Medical Science Pub Date : 2025-10-01 Epub Date: 2025-08-04 DOI:10.1292/jvms.24-0514

Akihisa Suwa

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引用次数: 0

摘要

一只14岁，阉割的雄性杂交猫出现体重减轻和鼻炎几个月，由于贫血和血小板减少而被转诊。全血细胞计数（CBC）显示严重的非再生性贫血（血细胞比容（HCT）， 9.7%）和血小板减少（0 /μL）。血清猫免疫缺陷病毒（FIV）抗体阳性。骨髓穿刺显示中度髓系增生，严重红系发育不全，巨核细胞发育不全。这只猫被诊断为纯红细胞发育不全（PRCA）和单核细胞血小板减少症（AMT），并接受皮质类固醇治疗，最终康复。第242天，骨髓抽吸显示红细胞和巨核细胞的产生。到第600天，没有药物治疗，两种疾病都没有复发。这是一只fiv感染的猫并发PRCA和AMT的记录病例。

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Pure red cell aplasia and amegakaryocytic thrombocytopenia in a cat.

A 14-year-old, castrated male mixed-breed cat presented with weight loss and rhinitis for several months and was referred due to anemia and thrombocytopenia. A complete blood cell count (CBC) revealed severe non-regenerative anemia (hematocrit (HCT), 9.7%) and thrombocytopenia (0 /μL). Serology was positive for feline immunodeficiency virus (FIV) antibodies. Bone marrow aspiration showed moderate myeloid hyperplasia, severe erythroid hypoplasia, and megakaryocytic hypoplasia. The cat was diagnosed with pure red cell aplasia (PRCA) and amegakaryocytic thrombocytopenia (AMT) and treated with corticosteroids, leading to recovery. On day 242, bone marrow aspirates showed erythroid and megakaryocytic cell production. By day 600, both diseases had not recurred without medication. This is the documented case of concurrent PRCA and AMT in an FIV-infected cat.

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来源期刊

Journal of Veterinary Medical Science 农林科学-兽医学

CiteScore

2.30

自引率

8.30%

发文量

230

审稿时长

9-18 weeks

期刊介绍： JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.