老年人群头面部默克尔细胞和鳞状细胞癌共存1例报告并文献复习

IF 0.6 4区医学 Q4 PATHOLOGY

Polish Journal of Pathology Pub Date : 2025-01-01 DOI:10.5114/pjp.2025.149383

Shiwei Zhang, Hongliang Ji, Pan Qin

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引用次数: 0

摘要

默克尔细胞癌（MCC）是一种罕见且高度侵袭性的神经内分泌癌类型，主要影响老年人暴露在阳光下的皮肤区域，特别是头颈部（41% -50%），其次是四肢（32-38%）。MCC可能与其他皮肤恶性肿瘤，如皮肤鳞状细胞癌（CSCC）、Bowen病和基底细胞癌有关。皮肤鳞状细胞癌是最常见的MCC并发肿瘤，特别是在皮肤暴露在阳光下的区域。在此，我们提出一个颅面区MCC和CSCC共存的病例，并对该主题的相关文献进行了广泛的回顾。

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Coexistence of head and face Merkel cell and squamous cell carcinomas in the elderly population - a case report and literature review.

Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroendocrine cancer type that predominantly impacts sun-exposed skin areas in the elderly, particularly the head and neck (41-50%), followed by the limbs (32-38%). There is likely an association between MCC and other cutaneous malignancies, such as cutaneous squamous cell carcinoma (CSCC), Bowen's disease, and basal cell carcinoma. Cutaneous squamous cell carcinoma is the most common concurrent tumor with MCC, especially in sun-exposed regions of the skin. Herein, we present a case of coexistence of MCC and CSCC in the craniofacial region, accompanied by an extensive review of relevant literature on this topic.

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来源期刊

Polish Journal of Pathology PATHOLOGY-

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Polish Journal of Pathology is an official magazine of the Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology. For the last 18 years of its presence on the market it has published more than 360 original papers and scientific reports, often quoted in reviewed foreign magazines. A new extended Scientific Board of the quarterly magazine comprises people with recognised achievements in pathomorphology and biology, including molecular biology and cytogenetics, as well as clinical oncology. Polish scientists who are working abroad and are international authorities have also been invited. Apart from presenting scientific reports, the magazine will also play a didactic and training role.