Geristore®在当代牙髓学中的作用综述。

Q3 Dentistry
Iranian Endodontic Journal Pub Date : 2025-01-01 Epub Date: 2025-07-19 DOI:10.22037/iej.v20i1.48268
Mahsa Radafshar, Ardavan Parhizkar
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引用次数: 0

摘要

简介:Geristore®(GS)是一种先进的双固化树脂改性玻璃离聚体,具有良好的生物和物理性能,包括生物相容性、氟化物释放和优异的密封能力。最初是为修复目的而开发的,它的临床多功能性已经扩展到牙髓学。当前的综述主要旨在评估GS作为生物材料在现代牙髓治疗中的生物学特性、牙髓治疗应用以及可能的临床潜力。方法:在主要数据库(MEDLINE、PubMed、Scopus、Cochrane、EMBASE、谷歌Scholar和灰色文献)中进行全面的文献检索,不受日期和/或语言的限制。鉴定、筛选、调查和批判性分析了GS的成分、特性和牙髓治疗用途的相关同行评审研究。结果:Geristore®在根端填充、穿孔修复、重要牙髓治疗、逆行重要牙髓治疗、孔内屏障放置和颈外吸收管理等根管治疗中表现出了良好的效果。此外,各种研究都强调了其良好的软组织相容性、密封能力(即使在潮湿环境中)以及可接受的机械性能。然而,与硅酸钙基材料(如矿物三氧化物骨料)相比,有一些局限性,包括抗弯强度降低和细胞毒性较高。结论:Geristore®呈现为临床有用的替代特定根管适应症,其中生物相容性,密封性和易处理似乎至关重要。然而,进一步的高质量临床试验和比较研究是必要的,以验证其长期性能,并确定其相对于已建立的根管生物材料的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Critical Review of the Role of Geristore® in Contemporary Endodontics.

A Critical Review of the Role of Geristore® in Contemporary Endodontics.

A Critical Review of the Role of Geristore® in Contemporary Endodontics.

Introduction: Geristore® (GS) is an advanced dual-cure resin-modified glass ionomer with favourable biological and physical properties, including biocompatibility, fluoride release, and excellent sealing ability. Originally developed for restorative purposes, its clinical versatility has nonetheless extended into endodontics. The current critical review primarily aims to evaluate the biological characteristics, endodontic applications, and possible clinical potential of GS as a biomaterial in modern endodontic practice.

Methods: A comprehensive literature search was conducted across major databases (MEDLINE, PubMed, Scopus, Cochrane, EMBASE, Google Scholar, and grey literature) without restrictions on date and/or language. Relevant peer-reviewed studies on the composition, properties, and endodontic uses of GS were identified, screened, investigated, and critically analysed.

Results: Geristore® has demonstrated promising outcomes in endodontic procedures, e.g., root-end filling, perforation repair, vital pulp therapy, retrograde vital pulp therapy, intra-orifice barrier placement and the management of external cervical resorption, Additionally, various studies have highlighted its favourable soft tissue compatibility, sealing ability (even in moist environments) as well as its acceptable mechanical properties. However, certain limitations, including reduced flexural strength and higher cytotoxicity compared to calcium silicate-based materials, such as mineral trioxide aggregate, have been reported.

Conclusion: Geristore® presents as a clinically useful alternative for specific endodontic indications where biocompatibility, sealability, and ease of handling seem critical. However, further high-quality clinical trials and comparative studies are essential to validate its long-term performance and establish its role relative to established endodontic biomaterials.

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来源期刊
Iranian Endodontic Journal
Iranian Endodontic Journal Dentistry-Dentistry (all)
CiteScore
1.30
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The Iranian Endodontic Journal (IEJ) is an international peer-reviewed biomedical publication, the aim of which is to provide a scientific medium of communication for researchers throughout the globe. IEJ aims to publish the highest quality articles, both clinical and scientific, on all aspects of Endodontics. The journal is an official Journal of the Iranian Center for Endodontic Research (ICER) and the Iranian Association of Endodontists (IAE). The Journal welcomes articles related to the scientific or applied aspects of endodontics e.g. original researches, systematic reviews, meta-analyses, review articles, clinical trials, case series/reports, hypotheses, letters to the editor, etc. From the beginning (i.e. since 2006), the IEJ was the first open access endodontic journal in the world, which gave readers free and instant access to published articles and enabling them faster discovery of the latest endodontic research.
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