{"title":"综合治疗对糖尿病足病患者康复管理的疗效及血液流变学状况的改善","authors":"Shuo Li, Yan Liu, Yu Chen","doi":"10.2147/DMSO.S526919","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of a multimodal intervention-comprising rehabilitation management and foot preventive measures-on clinical outcomes, hemorheological parameters, and vascular endothelial function in patients with diabetic foot (DF).</p><p><strong>Methods: </strong>This retrospective study included 126 <i>DF</i> patients admitted to our hospital from February 2023 to April 2024. Patients were divided into a control group (n = 63, receiving routine nursing care) and an intervention group (n = 63, receiving routine care plus rehabilitation management combined with foot preventive measures). Key outcome measures included: (1) clinical efficacy; (2) hemorheological indicators-whole blood low-shear viscosity (WBLSV), high-shear viscosity (WBHSV), fibrinogen (FIB), and erythrocyte deformability index (EDI); (3) vascular endothelial function indicators-endothelin (ET), basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF), and calcitonin gene-related peptide (CGRP); (4) self-management ability-Adult Health Self-Management Scale (AHSMSRS), General Self-Efficacy Scale (GSES); and (5) nursing satisfaction-Newcastle Nursing Service Satisfaction Scale (NSNS).</p><p><strong>Results: </strong>The intervention group had a significantly higher total treatment efficacy rate (92.06% vs 77.78%, P < 0.05). Post-intervention hemorheological parameters (WBLSV, WBHSV, FIB, EDI) and endothelial markers (ET, bFGF, VEGF, CGRP) showed greater improvement in the intervention group (P < 0.05). Similarly, AHSMSRS scores declined and GSES scores improved more markedly in the intervention group (P < 0.05). Nursing satisfaction was also higher (96.83% vs 71.43%, P < 0.05).</p><p><strong>Conclusion: </strong>Compared with routine nursing care alone, the multimodal intervention strategy may improve clinical efficacy, hemorheology, endothelial function, self-management capabilities, and patient satisfaction in diabetic foot care. However, these findings should be interpreted with caution given the retrospective design.</p>","PeriodicalId":11116,"journal":{"name":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy","volume":"18 ","pages":"2561-2571"},"PeriodicalIF":3.0000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317705/pdf/","citationCount":"0","resultStr":"{\"title\":\"The Effectivity MultiModality Treatment on Rehabilitation Management of Diabetic Foot Disease Patients for Improvement of Clinical Efficacy & Hemorheological Status.\",\"authors\":\"Shuo Li, Yan Liu, Yu Chen\",\"doi\":\"10.2147/DMSO.S526919\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the effectiveness of a multimodal intervention-comprising rehabilitation management and foot preventive measures-on clinical outcomes, hemorheological parameters, and vascular endothelial function in patients with diabetic foot (DF).</p><p><strong>Methods: </strong>This retrospective study included 126 <i>DF</i> patients admitted to our hospital from February 2023 to April 2024. Patients were divided into a control group (n = 63, receiving routine nursing care) and an intervention group (n = 63, receiving routine care plus rehabilitation management combined with foot preventive measures). Key outcome measures included: (1) clinical efficacy; (2) hemorheological indicators-whole blood low-shear viscosity (WBLSV), high-shear viscosity (WBHSV), fibrinogen (FIB), and erythrocyte deformability index (EDI); (3) vascular endothelial function indicators-endothelin (ET), basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF), and calcitonin gene-related peptide (CGRP); (4) self-management ability-Adult Health Self-Management Scale (AHSMSRS), General Self-Efficacy Scale (GSES); and (5) nursing satisfaction-Newcastle Nursing Service Satisfaction Scale (NSNS).</p><p><strong>Results: </strong>The intervention group had a significantly higher total treatment efficacy rate (92.06% vs 77.78%, P < 0.05). Post-intervention hemorheological parameters (WBLSV, WBHSV, FIB, EDI) and endothelial markers (ET, bFGF, VEGF, CGRP) showed greater improvement in the intervention group (P < 0.05). Similarly, AHSMSRS scores declined and GSES scores improved more markedly in the intervention group (P < 0.05). Nursing satisfaction was also higher (96.83% vs 71.43%, P < 0.05).</p><p><strong>Conclusion: </strong>Compared with routine nursing care alone, the multimodal intervention strategy may improve clinical efficacy, hemorheology, endothelial function, self-management capabilities, and patient satisfaction in diabetic foot care. 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引用次数: 0
摘要
目的：评价包括康复管理和足部预防措施在内的多模式干预对糖尿病足（DF）患者临床结局、血液流变学参数和血管内皮功能的影响。方法：对2023年2月至2024年4月我院收治的126例DF患者进行回顾性研究。将患者分为对照组（63例，给予常规护理）和干预组（63例，给予常规护理加康复管理结合足部预防措施）。主要结局指标包括：(1)临床疗效；(2)血液流变学指标——全血低剪切粘度（WBLSV）、高剪切粘度（WBHSV）、纤维蛋白原（FIB）、红细胞变形指数（EDI）；(3)血管内皮功能指标——内皮素（ET）、碱性成纤维细胞生长因子（bFGF）、血管内皮生长因子（VEGF）、降钙素基因相关肽（CGRP）；(4)自我管理能力——成人健康自我管理量表（AHSMSRS）、一般自我效能量表（GSES）；(5)护理满意度-纽卡斯尔护理服务满意度量表（NSNS）。结果：干预组总有效率明显高于对照组（92.06% vs 77.78%, P < 0.05）。干预后血液流变学参数（WBLSV、WBHSV、FIB、EDI）和内皮标志物（ET、bFGF、VEGF、CGRP）在干预组有较大改善（P < 0.05）。干预组AHSMSRS评分明显下降，GSES评分明显提高（P < 0.05）。护理满意度也较高（96.83% vs 71.43%, P < 0.05）。结论：与单纯的常规护理相比，多模式干预策略可提高糖尿病足护理的临床疗效、血液流变学、内皮功能、自我管理能力和患者满意度。然而，考虑到回顾性设计，这些发现应谨慎解释。
The Effectivity MultiModality Treatment on Rehabilitation Management of Diabetic Foot Disease Patients for Improvement of Clinical Efficacy & Hemorheological Status.
Objective: To evaluate the effectiveness of a multimodal intervention-comprising rehabilitation management and foot preventive measures-on clinical outcomes, hemorheological parameters, and vascular endothelial function in patients with diabetic foot (DF).
Methods: This retrospective study included 126 DF patients admitted to our hospital from February 2023 to April 2024. Patients were divided into a control group (n = 63, receiving routine nursing care) and an intervention group (n = 63, receiving routine care plus rehabilitation management combined with foot preventive measures). Key outcome measures included: (1) clinical efficacy; (2) hemorheological indicators-whole blood low-shear viscosity (WBLSV), high-shear viscosity (WBHSV), fibrinogen (FIB), and erythrocyte deformability index (EDI); (3) vascular endothelial function indicators-endothelin (ET), basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF), and calcitonin gene-related peptide (CGRP); (4) self-management ability-Adult Health Self-Management Scale (AHSMSRS), General Self-Efficacy Scale (GSES); and (5) nursing satisfaction-Newcastle Nursing Service Satisfaction Scale (NSNS).
Results: The intervention group had a significantly higher total treatment efficacy rate (92.06% vs 77.78%, P < 0.05). Post-intervention hemorheological parameters (WBLSV, WBHSV, FIB, EDI) and endothelial markers (ET, bFGF, VEGF, CGRP) showed greater improvement in the intervention group (P < 0.05). Similarly, AHSMSRS scores declined and GSES scores improved more markedly in the intervention group (P < 0.05). Nursing satisfaction was also higher (96.83% vs 71.43%, P < 0.05).
Conclusion: Compared with routine nursing care alone, the multimodal intervention strategy may improve clinical efficacy, hemorheology, endothelial function, self-management capabilities, and patient satisfaction in diabetic foot care. However, these findings should be interpreted with caution given the retrospective design.
期刊介绍：
An international, peer-reviewed, open access, online journal. The journal is committed to the rapid publication of the latest laboratory and clinical findings in the fields of diabetes, metabolic syndrome and obesity research. Original research, review, case reports, hypothesis formation, expert opinion and commentaries are all considered for publication.
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