{"title":"西孟加拉邦城区有或无2型糖尿病的老年人中3型糖尿病的预测因素","authors":"Anuska Maity, Subarna Sinha Mahapatra, Piush Pandey, Rakesh Kumar, Soumit Roy, Raghunath Misra, Sumit Kumar Dash","doi":"10.4103/aam.aam_153_25","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>In view of the latest evidence, dementia is also regarded as type 3 diabetes mellitus (T3DM) due to the important role of brain insulin resistance in its pathogenesis. Our study objectives were to find out the proportion and predictors of mild cognitive impairment (MCI) and T3DM (dementia) among the elderly people living with and without type 2 diabetes mellitus (T2DM) attending a medical college outpatient department (OPD).</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted comparing elderly patients from diabetes clinic OPD and general medicine OPD of a medical college in West Bengal. Two groups consisting of 70 participants in each, based on their diabetic status, were made. A predesigned, pretested, and semistructured schedule was prepared incorporating the Alzheimer's questionnaire (AQ). Chi-square and logistics regression were used to find the predictors of MCI, T3DM in each group, and the median AQ score was compared using Mann-Whitney U-test.</p><p><strong>Results: </strong>Among people with T2DM (PwD), 27 (38.6%) had MCI, and 17 (24.3%) had T3DM. Among people without T2DM, 45 (64.3%) had normal cognition. There was a significant difference in the median AQ score of both groups. A significant association was found between cognitive status and T2DM status (P = 0.004). Among diabetics, female gender (adjusted odds ratio [AOR]: 15.38, P = 0.012), primary education (AOR 27.14, P = 0.027), and family history of dementia (AOR 27.65, P = 0.013) were found to be predictors of dementia.</p><p><strong>Conclusion: </strong>Significant difference in the proportion of MCI and T3DM among elderly PwD and elderly nondiabetics was noted. Regular screening for T2DM and cognitive status is need of the hour.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Predictors of Type 3 Diabetes Mellitus among Elderly Living with and without Type 2 Diabetes Mellitus: A Cross-sectional Study in the Urban Area of West Bengal.\",\"authors\":\"Anuska Maity, Subarna Sinha Mahapatra, Piush Pandey, Rakesh Kumar, Soumit Roy, Raghunath Misra, Sumit Kumar Dash\",\"doi\":\"10.4103/aam.aam_153_25\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>In view of the latest evidence, dementia is also regarded as type 3 diabetes mellitus (T3DM) due to the important role of brain insulin resistance in its pathogenesis. Our study objectives were to find out the proportion and predictors of mild cognitive impairment (MCI) and T3DM (dementia) among the elderly people living with and without type 2 diabetes mellitus (T2DM) attending a medical college outpatient department (OPD).</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted comparing elderly patients from diabetes clinic OPD and general medicine OPD of a medical college in West Bengal. Two groups consisting of 70 participants in each, based on their diabetic status, were made. A predesigned, pretested, and semistructured schedule was prepared incorporating the Alzheimer's questionnaire (AQ). Chi-square and logistics regression were used to find the predictors of MCI, T3DM in each group, and the median AQ score was compared using Mann-Whitney U-test.</p><p><strong>Results: </strong>Among people with T2DM (PwD), 27 (38.6%) had MCI, and 17 (24.3%) had T3DM. Among people without T2DM, 45 (64.3%) had normal cognition. There was a significant difference in the median AQ score of both groups. A significant association was found between cognitive status and T2DM status (P = 0.004). Among diabetics, female gender (adjusted odds ratio [AOR]: 15.38, P = 0.012), primary education (AOR 27.14, P = 0.027), and family history of dementia (AOR 27.65, P = 0.013) were found to be predictors of dementia.</p><p><strong>Conclusion: </strong>Significant difference in the proportion of MCI and T3DM among elderly PwD and elderly nondiabetics was noted. Regular screening for T2DM and cognitive status is need of the hour.</p>\",\"PeriodicalId\":7938,\"journal\":{\"name\":\"Annals of African Medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-08-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of African Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/aam.aam_153_25\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of African Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/aam.aam_153_25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
根据最新的证据，由于脑胰岛素抵抗在其发病机制中起重要作用，痴呆症也被视为3型糖尿病（T3DM）。我们的研究目的是了解在某医科大学门诊就诊的有2型糖尿病（T2DM）和无2型糖尿病（T2DM）的老年人中轻度认知障碍（MCI）和T3DM（痴呆）的比例及其预测因素。材料与方法：对西孟加拉邦某医学院糖尿病门诊门诊与普通内科门诊的老年患者进行横断面研究。根据患者的糖尿病状况，分为两组，每组70人。预先设计、预先测试和半结构化的时间表包括阿尔茨海默病问卷（AQ）。采用卡方回归和logistic回归寻找各组MCI、T3DM的预测因子，采用Mann-Whitney u检验比较AQ得分中位数。结果：在T2DM （PwD）患者中，27例（38.6%）患有MCI， 17例（24.3%）患有T3DM。在非T2DM人群中，45人（64.3%）认知正常。两组的平均智商得分差异有统计学意义。认知状态与T2DM状态之间存在显著相关性（P = 0.004）。在糖尿病患者中，女性（校正优势比[AOR]: 15.38, P = 0.012）、小学教育程度（AOR 27.14, P = 0.027）、痴呆家族史（AOR 27.65, P = 0.013）是痴呆的预测因素。结论：老年PwD患者与老年非糖尿病患者MCI和T3DM比例存在显著差异。定期筛查2型糖尿病和认知状况是必要的。
Predictors of Type 3 Diabetes Mellitus among Elderly Living with and without Type 2 Diabetes Mellitus: A Cross-sectional Study in the Urban Area of West Bengal.
Introduction: In view of the latest evidence, dementia is also regarded as type 3 diabetes mellitus (T3DM) due to the important role of brain insulin resistance in its pathogenesis. Our study objectives were to find out the proportion and predictors of mild cognitive impairment (MCI) and T3DM (dementia) among the elderly people living with and without type 2 diabetes mellitus (T2DM) attending a medical college outpatient department (OPD).
Materials and methods: A cross-sectional study was conducted comparing elderly patients from diabetes clinic OPD and general medicine OPD of a medical college in West Bengal. Two groups consisting of 70 participants in each, based on their diabetic status, were made. A predesigned, pretested, and semistructured schedule was prepared incorporating the Alzheimer's questionnaire (AQ). Chi-square and logistics regression were used to find the predictors of MCI, T3DM in each group, and the median AQ score was compared using Mann-Whitney U-test.
Results: Among people with T2DM (PwD), 27 (38.6%) had MCI, and 17 (24.3%) had T3DM. Among people without T2DM, 45 (64.3%) had normal cognition. There was a significant difference in the median AQ score of both groups. A significant association was found between cognitive status and T2DM status (P = 0.004). Among diabetics, female gender (adjusted odds ratio [AOR]: 15.38, P = 0.012), primary education (AOR 27.14, P = 0.027), and family history of dementia (AOR 27.65, P = 0.013) were found to be predictors of dementia.
Conclusion: Significant difference in the proportion of MCI and T3DM among elderly PwD and elderly nondiabetics was noted. Regular screening for T2DM and cognitive status is need of the hour.
期刊介绍：
The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.
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