{"title":"社区障碍在药物可得性和药物使用之间的关联中的作用:一个有调节的中介分析","authors":"Beidi Dong , Brianna Camero , David Weisburd , Clair Uding","doi":"10.1016/j.drugalcdep.2025.112811","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Drug availability plays a crucial role in shaping drug use behavior. This study examines how reported drug presence, operationalized as living on a drug hot spot street, influences self-reported drug use through perceived drug availability and whether community disorder moderates this relationship.</div></div><div><h3>Methods</h3><div>This cross-sectional study analyzed survey data from 3738 respondents residing on 449 street segments in Baltimore, Maryland (August 2013 – June 2014), categorized as crime hot spots or non-hot spots. Logistic regression models with robust standard errors estimated the direct association between reported drug presence and self-reported drug use, as well as the indirect association mediated through perceived drug availability. Additionally, a moderated mediation analysis tested whether community disorder conditioned the indirect pathway.</div></div><div><h3>Results</h3><div>The relationship between reported drug presence and self-reported drug use was primarily indirect, operating through perceived availability. When perceived availability was included, the odds ratio for reported drug presence decreased from 1.19 [95 % CI: 1.00, 1.40] to 1.09 [95 % CI: 0.92, 1.29], while perceived availability was strongly associated with self-reported drug use (odds ratio = 1.45 [95 % CI: 1.23, 1.72]). However, this indirect pathway was statistically significant only in areas with lower levels of community disorder but insignificant in high-disorder settings.</div></div><div><h3>Conclusions</h3><div>Perceptions of drug availability significantly influence drug use behavior. While reducing perceived availability may be particularly effective in lower-disorder areas, addressing drug use in vulnerable, high-disorder settings requires a comprehensive, cross-sector approach that improves environmental conditions and addresses broader socioeconomic factors contributing to disorder and drug use.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"275 ","pages":"Article 112811"},"PeriodicalIF":3.6000,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The role of community disorder in the association between drug availability and drug use: A moderated mediation analysis\",\"authors\":\"Beidi Dong , Brianna Camero , David Weisburd , Clair Uding\",\"doi\":\"10.1016/j.drugalcdep.2025.112811\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Drug availability plays a crucial role in shaping drug use behavior. This study examines how reported drug presence, operationalized as living on a drug hot spot street, influences self-reported drug use through perceived drug availability and whether community disorder moderates this relationship.</div></div><div><h3>Methods</h3><div>This cross-sectional study analyzed survey data from 3738 respondents residing on 449 street segments in Baltimore, Maryland (August 2013 – June 2014), categorized as crime hot spots or non-hot spots. Logistic regression models with robust standard errors estimated the direct association between reported drug presence and self-reported drug use, as well as the indirect association mediated through perceived drug availability. Additionally, a moderated mediation analysis tested whether community disorder conditioned the indirect pathway.</div></div><div><h3>Results</h3><div>The relationship between reported drug presence and self-reported drug use was primarily indirect, operating through perceived availability. When perceived availability was included, the odds ratio for reported drug presence decreased from 1.19 [95 % CI: 1.00, 1.40] to 1.09 [95 % CI: 0.92, 1.29], while perceived availability was strongly associated with self-reported drug use (odds ratio = 1.45 [95 % CI: 1.23, 1.72]). However, this indirect pathway was statistically significant only in areas with lower levels of community disorder but insignificant in high-disorder settings.</div></div><div><h3>Conclusions</h3><div>Perceptions of drug availability significantly influence drug use behavior. While reducing perceived availability may be particularly effective in lower-disorder areas, addressing drug use in vulnerable, high-disorder settings requires a comprehensive, cross-sector approach that improves environmental conditions and addresses broader socioeconomic factors contributing to disorder and drug use.</div></div>\",\"PeriodicalId\":11322,\"journal\":{\"name\":\"Drug and alcohol dependence\",\"volume\":\"275 \",\"pages\":\"Article 112811\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Drug and alcohol dependence\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0376871625002649\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug and alcohol dependence","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0376871625002649","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
The role of community disorder in the association between drug availability and drug use: A moderated mediation analysis
Introduction
Drug availability plays a crucial role in shaping drug use behavior. This study examines how reported drug presence, operationalized as living on a drug hot spot street, influences self-reported drug use through perceived drug availability and whether community disorder moderates this relationship.
Methods
This cross-sectional study analyzed survey data from 3738 respondents residing on 449 street segments in Baltimore, Maryland (August 2013 – June 2014), categorized as crime hot spots or non-hot spots. Logistic regression models with robust standard errors estimated the direct association between reported drug presence and self-reported drug use, as well as the indirect association mediated through perceived drug availability. Additionally, a moderated mediation analysis tested whether community disorder conditioned the indirect pathway.
Results
The relationship between reported drug presence and self-reported drug use was primarily indirect, operating through perceived availability. When perceived availability was included, the odds ratio for reported drug presence decreased from 1.19 [95 % CI: 1.00, 1.40] to 1.09 [95 % CI: 0.92, 1.29], while perceived availability was strongly associated with self-reported drug use (odds ratio = 1.45 [95 % CI: 1.23, 1.72]). However, this indirect pathway was statistically significant only in areas with lower levels of community disorder but insignificant in high-disorder settings.
Conclusions
Perceptions of drug availability significantly influence drug use behavior. While reducing perceived availability may be particularly effective in lower-disorder areas, addressing drug use in vulnerable, high-disorder settings requires a comprehensive, cross-sector approach that improves environmental conditions and addresses broader socioeconomic factors contributing to disorder and drug use.
期刊介绍:
Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.