Rosai-Dorfman病的中枢神经系统表现。

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Journal of the Pakistan Medical Association Pub Date : 2025-07-01 DOI:10.47391/JPMA.25-57

Zanib Javed, Moeez Tariq, Muhammad Shahzad Shamim

{"title":"Rosai-Dorfman病的中枢神经系统表现。","authors":"Zanib Javed, Moeez Tariq, Muhammad Shahzad Shamim","doi":"10.47391/JPMA.25-57","DOIUrl":null,"url":null,"abstract":"Rosai-Dorfman disease (RDD) is an abnormal proliferation of histiocytes which manifest classically as bilateral cervical lymphadenopathy and B symptoms. Rarely, it also presents with involvement of other systems. CNS RDD is extremely rare and accounts for 5% of reported cases. The clinical picture is dependent on the area of CNS affected. It is mostly diagnosed on MRI, however, it may be confused with a meningioma, dural based metastases, lymphoma, sarcoidosis, etc. Diagnosis is based on typical histopathological features. The recommended treatment for symptomatic CNS manifestations of RDD is complete surgical resection.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 7","pages":"1148-1150"},"PeriodicalIF":0.8000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CNS Manifestations of Rosai-Dorfman Disease.\",\"authors\":\"Zanib Javed, Moeez Tariq, Muhammad Shahzad Shamim\",\"doi\":\"10.47391/JPMA.25-57\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Rosai-Dorfman disease (RDD) is an abnormal proliferation of histiocytes which manifest classically as bilateral cervical lymphadenopathy and B symptoms. Rarely, it also presents with involvement of other systems. CNS RDD is extremely rare and accounts for 5% of reported cases. The clinical picture is dependent on the area of CNS affected. It is mostly diagnosed on MRI, however, it may be confused with a meningioma, dural based metastases, lymphoma, sarcoidosis, etc. Diagnosis is based on typical histopathological features. The recommended treatment for symptomatic CNS manifestations of RDD is complete surgical resection.\",\"PeriodicalId\":54369,\"journal\":{\"name\":\"Journal of the Pakistan Medical Association\",\"volume\":\"75 7\",\"pages\":\"1148-1150\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Pakistan Medical Association\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.47391/JPMA.25-57\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Pakistan Medical Association","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.47391/JPMA.25-57","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

摘要

rossai - dorfman病（RDD）是一种组织细胞的异常增生，典型表现为双侧宫颈淋巴结病和B症状。很少情况下，它也会涉及到其他系统。中枢神经系统RDD极为罕见，占报告病例的5%。临床表现取决于中枢神经系统受影响的区域。它主要通过MRI诊断，然而，它可能与脑膜瘤、硬脑膜转移、淋巴瘤、结节病等相混淆。诊断基于典型的组织病理学特征。对于RDD的症状性中枢神经系统表现，推荐的治疗方法是完全手术切除。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

CNS Manifestations of Rosai-Dorfman Disease.

Rosai-Dorfman disease (RDD) is an abnormal proliferation of histiocytes which manifest classically as bilateral cervical lymphadenopathy and B symptoms. Rarely, it also presents with involvement of other systems. CNS RDD is extremely rare and accounts for 5% of reported cases. The clinical picture is dependent on the area of CNS affected. It is mostly diagnosed on MRI, however, it may be confused with a meningioma, dural based metastases, lymphoma, sarcoidosis, etc. Diagnosis is based on typical histopathological features. The recommended treatment for symptomatic CNS manifestations of RDD is complete surgical resection.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of the Pakistan Medical Association Medicine-General Medicine

CiteScore

1.10

自引率

11.10%

发文量

983

审稿时长

3-6 weeks

期刊介绍： Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.