年度回顾：胃肠病学和肝病学最佳论文评选2024。

IF 6.7 2区医学 Q1 MEDICINE, GENERAL & INTERNAL

Mayo Clinic proceedings Pub Date : 2025-09-01 DOI:10.1016/j.mayocp.2025.06.001

Michael Camilleri MD, DSc , Evan S. Dellon MD, MPH

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引用次数: 0

摘要

这篇综述讨论了胃肠病学和肝病学中与普通内科医生相关的话题。这些主题是根据2024年在顶级普通医学期刊（《新英格兰医学杂志》、《美国医学协会杂志》、《内科医学年鉴》、《柳叶刀》）上发表的文章选择的，通常还会补充在顶级胃肠病学期刊上发表的与同一主题有关的文章。普通内科医生可能是其中一些疾病的主要提供者，或者是第一个评估症状的人——比如不受控制的胃灼热；吞咽困难，这越来越被认为与过敏机制有关，包括食管嗜酸性粒细胞浸润；肠易激综合征；肠促胰岛素治疗（胰高血糖素样肽1和胰高血糖素依赖性胰岛素肽激动剂）对肥胖、代谢相关脂肪性肝炎或脂肪性肝病的影响，以及通过新的血液或粪便标志物筛查结直肠癌的影响。或者，内科医生可以为更复杂的疾病提供连续性的护理，包括胰腺导管腺癌的新诊断方法，局部晚期错配修复缺陷结肠直肠癌的免疫治疗，以及原发性胆管炎等罕见肝脏疾病的治疗。这些主题说明了2024年在胃肠道和肝脏疾病的诊断和管理方面取得的令人印象深刻的进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Year in Review: Selection of Best Papers in Gastroenterology and Hepatology 2024

This review addresses selected topics in gastroenterology and hepatology that are of interest and relevance to general internists. The topics were selected on the basis of publications in 2024 in top general medicine journals (New England Journal of Medicine, Journal of the American Medical Association, Annals of Internal Medicine, Lancet), often complemented with publications in the top gastroenterology journals pertaining to the same themes. General internists may be the primary providers for some of these diseases or the first to evaluate symptoms—such as uncontrolled heartburn; dysphagia, which is increasingly recognized as being associated with allergic mechanisms including eosinophil infiltration of the esophagus; irritable bowel syndrome; and the effects of incretin therapies (glucagon-like peptide 1 and glucagon-dependent insulinotropic peptide agonists) on obesity, metabolic-associated steatohepatitis, or steatotic liver diseases—and to screen for colorectal cancer by novel blood or stool markers. Alternatively, internists may provide continuity of care for more complex diseases, including a novel diagnostic approach to pancreatic ductal adenocarcinoma, immunotherapy for locally advanced mismatch repair–deficient colorectal cancer, and treatment of rarer liver diseases such as primary biliary cholangitis. These topics illustrate impressive advances in 2024 in the diagnosis and management of diseases affecting the gastrointestinal tract and liver.

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来源期刊

Mayo Clinic proceedings 医学-医学：内科

CiteScore

16.80

自引率

1.10%

发文量

383

审稿时长

37 days

期刊介绍： Mayo Clinic Proceedings is a premier peer-reviewed clinical journal in general medicine. Sponsored by Mayo Clinic, it is one of the most widely read and highly cited scientific publications for physicians. Since 1926, Mayo Clinic Proceedings has continuously published articles that focus on clinical medicine and support the professional and educational needs of its readers. The journal welcomes submissions from authors worldwide and includes Nobel-prize-winning research in its content. With an Impact Factor of 8.9, Mayo Clinic Proceedings is ranked #20 out of 167 journals in the Medicine, General and Internal category, placing it in the top 12% of these journals. It invites manuscripts on clinical and laboratory medicine, health care policy and economics, medical education and ethics, and related topics.