Maya K Keefer, Margaret A Mooring, Kim Love, Jennifer Halleran, Derek Foster, Kelley M Varner
{"title":"与3点椎旁远端阻滞相比,4点椎旁远端阻滞可改善术后即刻镇痛的生理指标。","authors":"Maya K Keefer, Margaret A Mooring, Kim Love, Jennifer Halleran, Derek Foster, Kelley M Varner","doi":"10.2460/javma.25.02.0120","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To determine differences in surgical and postoperative analgesia between 3-site distal paravertebral (DPV) blocks and modified 4-site DPV blocks.</p><p><strong>Methods: </strong>12 healthy dairy or dairy cross steers were randomized into 1 of 2 treatments, 3-site DPV block (3DPV) or 4-site DPV block (4DPV); 2 mg/kg of 2% lidocaine was administered at each site-lumbar vertebrae 1, 2, and 4 in the 3DPV group (6 mg/kg), and an additional injection at lumbar vertebrae 3 for the 4DPV group (8 mg/kg). Heart and respiratory rates, temperature, reaction scores, and surgical condition scores were collected. Postoperative pain scores and physiologic data were collected for 24 hours following surgery. An ordinal logistic mixed-effects model was used to compare surgical conditions, reaction scores, and pain scores. A linear mixed-effects model was used for normally distributed data.</p><p><strong>Results: </strong>The success rate of 3DPV blockade was 5 of 6 (83%), and that for 4DPV was 6 of 6 (100%). Only 11 steers were included in the data analysis due to the failed block. The 4DPV group had lower respiratory rates following the return to stall (32 ± 3 vs 44 ± 4 breaths/min; P < .019). Additionally, the 4DPV group had significantly lower heart rates immediately following the return to the stall (62 ± 8 vs 88 ± 9 beats/min; P < .036). No differences in pain scores or intraoperative conditions were identified.</p><p><strong>Conclusions: </strong>Adding an injection site at L3 in a DPV reduced postoperative heart rate and respiratory rate in steers following laparotomy.</p><p><strong>Clinical relevance: </strong>Adding a fourth injection site at L3 decreases physiologic indicators of postoperative discomfort.</p>","PeriodicalId":14658,"journal":{"name":"Javma-journal of The American Veterinary Medical Association","volume":" ","pages":"1-5"},"PeriodicalIF":1.8000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Four-site distal paravertebral blocks improve physiologic indicators of analgesia in the immediate postoperative period as opposed to a 3-site distal paravertebral block.\",\"authors\":\"Maya K Keefer, Margaret A Mooring, Kim Love, Jennifer Halleran, Derek Foster, Kelley M Varner\",\"doi\":\"10.2460/javma.25.02.0120\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To determine differences in surgical and postoperative analgesia between 3-site distal paravertebral (DPV) blocks and modified 4-site DPV blocks.</p><p><strong>Methods: </strong>12 healthy dairy or dairy cross steers were randomized into 1 of 2 treatments, 3-site DPV block (3DPV) or 4-site DPV block (4DPV); 2 mg/kg of 2% lidocaine was administered at each site-lumbar vertebrae 1, 2, and 4 in the 3DPV group (6 mg/kg), and an additional injection at lumbar vertebrae 3 for the 4DPV group (8 mg/kg). Heart and respiratory rates, temperature, reaction scores, and surgical condition scores were collected. Postoperative pain scores and physiologic data were collected for 24 hours following surgery. An ordinal logistic mixed-effects model was used to compare surgical conditions, reaction scores, and pain scores. A linear mixed-effects model was used for normally distributed data.</p><p><strong>Results: </strong>The success rate of 3DPV blockade was 5 of 6 (83%), and that for 4DPV was 6 of 6 (100%). Only 11 steers were included in the data analysis due to the failed block. The 4DPV group had lower respiratory rates following the return to stall (32 ± 3 vs 44 ± 4 breaths/min; P < .019). Additionally, the 4DPV group had significantly lower heart rates immediately following the return to the stall (62 ± 8 vs 88 ± 9 beats/min; P < .036). No differences in pain scores or intraoperative conditions were identified.</p><p><strong>Conclusions: </strong>Adding an injection site at L3 in a DPV reduced postoperative heart rate and respiratory rate in steers following laparotomy.</p><p><strong>Clinical relevance: </strong>Adding a fourth injection site at L3 decreases physiologic indicators of postoperative discomfort.</p>\",\"PeriodicalId\":14658,\"journal\":{\"name\":\"Javma-journal of The American Veterinary Medical Association\",\"volume\":\" \",\"pages\":\"1-5\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Javma-journal of The American Veterinary Medical Association\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.2460/javma.25.02.0120\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Javma-journal of The American Veterinary Medical Association","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.2460/javma.25.02.0120","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Four-site distal paravertebral blocks improve physiologic indicators of analgesia in the immediate postoperative period as opposed to a 3-site distal paravertebral block.
Objective: To determine differences in surgical and postoperative analgesia between 3-site distal paravertebral (DPV) blocks and modified 4-site DPV blocks.
Methods: 12 healthy dairy or dairy cross steers were randomized into 1 of 2 treatments, 3-site DPV block (3DPV) or 4-site DPV block (4DPV); 2 mg/kg of 2% lidocaine was administered at each site-lumbar vertebrae 1, 2, and 4 in the 3DPV group (6 mg/kg), and an additional injection at lumbar vertebrae 3 for the 4DPV group (8 mg/kg). Heart and respiratory rates, temperature, reaction scores, and surgical condition scores were collected. Postoperative pain scores and physiologic data were collected for 24 hours following surgery. An ordinal logistic mixed-effects model was used to compare surgical conditions, reaction scores, and pain scores. A linear mixed-effects model was used for normally distributed data.
Results: The success rate of 3DPV blockade was 5 of 6 (83%), and that for 4DPV was 6 of 6 (100%). Only 11 steers were included in the data analysis due to the failed block. The 4DPV group had lower respiratory rates following the return to stall (32 ± 3 vs 44 ± 4 breaths/min; P < .019). Additionally, the 4DPV group had significantly lower heart rates immediately following the return to the stall (62 ± 8 vs 88 ± 9 beats/min; P < .036). No differences in pain scores or intraoperative conditions were identified.
Conclusions: Adding an injection site at L3 in a DPV reduced postoperative heart rate and respiratory rate in steers following laparotomy.
Clinical relevance: Adding a fourth injection site at L3 decreases physiologic indicators of postoperative discomfort.
期刊介绍:
Published twice monthly, this peer-reviewed, general scientific journal provides reports of clinical research, feature articles and regular columns of interest to veterinarians in private and public practice. The News and Classified Ad sections are posted online 10 days to two weeks before they are delivered in print.