Mustafa Ibas , Muruvvet Paksoy , Mehmet Nuri Elgormus , Hafize Uzun , Erkan Karatas
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Subgroup analysis was conducted for patients aged ≤7 years.</div></div><div><h3>Results</h3><div>The bleeding group had significantly higher preoperative NLR values compared to controls (2.72 ± 2.21 vs. 1.79 ± 0.72, p = 0.023). ROC analysis yielded an AUC of 0.632 for all patients and 0.697 for those aged ≤7 years. An NLR threshold of 2.35 provided 40 % sensitivity and 86 % specificity for predicting hemorrhage, while an NLR cut-off of 2.08 improved sensitivity (64 %) and specificity (83 %) in younger children. Multivariate analysis confirmed NLR as an independent predictor of postoperative bleeding (OR = 1.68, p = 0.016).</div></div><div><h3>Conclusion</h3><div>Elevated preoperative NLR is associated with an increased risk of postoperative hemorrhage after pediatric tonsillectomy, particularly in children aged ≤7 years. Preoperative NLR measurement may serve as a useful adjunct in perioperative risk stratification.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"197 ","pages":"Article 112505"},"PeriodicalIF":1.3000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Corrigendum to “Predictive value of preoperative neutrophil-to-lymphocyte ratio for post-tonsillectomy hemorrhage: Age-Specific insights from a pediatric cohort” [Int. J. Pediatr. 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引用次数: 0
摘要
目的:评价术前中性粒细胞与淋巴细胞比值(NLR)对小儿扁桃体切除术后出血的预测价值,并探讨其年龄特异性。方法:本回顾性研究纳入了2021年1月至2025年12月在单一三级中心接受扁桃体切除术的100名儿童患者。对50例术后出血患者和50例无出血患者进行分析。比较两组术前NLR值。采用受试者工作特征(ROC)曲线分析和多变量logistic回归评估NLR的预测能力。年龄≤7岁的患者进行亚组分析。结果:出血组术前NLR值明显高于对照组(2.72±2.21∶1.79±0.72,p = 0.023)。ROC分析显示,所有患者的AUC为0.632,年龄≤7岁的患者的AUC为0.697。NLR阈值2.35为预测出血提供了40%的敏感性和86%的特异性,而NLR临界值2.08则提高了年幼儿童出血的敏感性(64%)和特异性(83%)。多因素分析证实NLR是术后出血的独立预测因子(OR = 1.68, p = 0.016)。结论:术前NLR升高与儿童扁桃体切除术后出血风险增加相关,尤其是≤7岁的儿童。术前NLR测量可作为围手术期风险分层的有用辅助。
Corrigendum to “Predictive value of preoperative neutrophil-to-lymphocyte ratio for post-tonsillectomy hemorrhage: Age-Specific insights from a pediatric cohort” [Int. J. Pediatr. Otorhinolaryngol. 196 (2025) 112480]
Objective
To evaluate the predictive value of preoperative neutrophil-to-lymphocyte ratio (NLR) for postoperative hemorrhage following pediatric tonsillectomy and to explore its age-specific performance.
Methods
This retrospective study included 100 pediatric patients who underwent tonsillectomy at a single tertiary center between January 2021 and December 2025. Fifty patients with postoperative hemorrhage and 50 without bleeding were analyzed. Preoperative NLR values were compared between groups. Receiver operating characteristic (ROC) curve analysis and multivariate logistic regression were performed to assess the predictive capacity of NLR. Subgroup analysis was conducted for patients aged ≤7 years.
Results
The bleeding group had significantly higher preoperative NLR values compared to controls (2.72 ± 2.21 vs. 1.79 ± 0.72, p = 0.023). ROC analysis yielded an AUC of 0.632 for all patients and 0.697 for those aged ≤7 years. An NLR threshold of 2.35 provided 40 % sensitivity and 86 % specificity for predicting hemorrhage, while an NLR cut-off of 2.08 improved sensitivity (64 %) and specificity (83 %) in younger children. Multivariate analysis confirmed NLR as an independent predictor of postoperative bleeding (OR = 1.68, p = 0.016).
Conclusion
Elevated preoperative NLR is associated with an increased risk of postoperative hemorrhage after pediatric tonsillectomy, particularly in children aged ≤7 years. Preoperative NLR measurement may serve as a useful adjunct in perioperative risk stratification.
期刊介绍:
The purpose of the International Journal of Pediatric Otorhinolaryngology is to concentrate and disseminate information concerning prevention, cure and care of otorhinolaryngological disorders in infants and children due to developmental, degenerative, infectious, neoplastic, traumatic, social, psychiatric and economic causes. The Journal provides a medium for clinical and basic contributions in all of the areas of pediatric otorhinolaryngology. This includes medical and surgical otology, bronchoesophagology, laryngology, rhinology, diseases of the head and neck, and disorders of communication, including voice, speech and language disorders.