Estimation of non-traditional stable isotopes reference values for geological reference materials

The homogeneity of reference materials and the precision of their reference values are fundamental prerequisites for ensuring the accuracy of non-traditional stable isotope analysis. Nevertheless, the field currently suffers from a significant methodological gap in robust homogeneity assessment and reference value estimation protocols. To address this gap, we implemented an analytical framework that integrates data acquisition from the Geological and Environmental Reference Materials database (GeoReM) with rigorous quality control measures based on ISO (International Organization for Standardization) guidelines and the IAG Certification Protocol. This approach enabled us to systematically report the isotopic compositions of 14 non-traditional stable isotope systems along with 63 isotopic compositions. The statistical results show that most of reference materials are homogeneous. However, our investigation revealed notable difference in the δ⁷Li_LSVEC values of AGV-1 and AGV-2, indicating potential limitations in their reliability as Li isotope reference materials. Furthermore, the Mg isotopic composition of NIST SRM 980 exhibited substantial heterogeneity, corroborating previous research findings and raising concerns about its suitability for high-precision isotopic measurements. In conclusion, this study provides a comprehensive set of reference values for widely used materials and establishing a rigorous, standardized protocol for their estimation. Beyond these methodological advancements, the study provides actionable recommendations for the selection of reference materials, underscoring the critical role of material homogeneity and measurement precision in ensuring the reliability of isotopic analyses.