了解与急诊科高危青少年和年轻人滥用阿片类药物相关的风险和保护因素

IF 3.6 2区 医学 Q1 PSYCHIATRY
Erin E. Bonar , Meredith Kotov , Carrie Bourque , Patrick M. Carter , Sarah J. Clark , David W. Hutton , Kelley M. Kidwell , Cheryl A. King , Eve D. Losman , Sean Esteban McCabe , Kai Zheng , Maureen Walton
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引用次数: 0

摘要

背景:青少年和青壮年(AYAs)需要针对风险和保护因素量身定制的阿片类药物滥用/阿片类药物使用障碍预防策略。我们描述了一项随机对照试验中参加急诊科(EDs)的高危asa中与阿片类药物滥用相关的基线风险/保护因素。方法纳入了最近去过急诊科(16-30岁)并自我报告1)过去一年处方阿片类药物使用+滥用危险因素(即吸毒、酗酒、抑郁症状、自杀风险)或2)海洛因或处方阿片类药物滥用的人群。评估背景特征和风险/保护因素的措施。分析根据参与者是否报告阿片类药物滥用或有滥用风险来比较他们。结果共入组1155例(男性27.5%);79.5%报告阿片类药物使用+危险因素,20.5%报告阿片类药物滥用。在未经调整的分析中,与阿片类药物使用+危险因素的人相比,阿片类药物滥用的人更有可能报告:男性、黑人/非裔美国人种族、接受公共援助、粮食不安全、更强烈的阿片类药物使用动机、更多的药物使用、先前的自杀企图、暴力参与和更大的冲动。他们还报告了较低的社会支持、亲社会活动和避免物质的自我效能。在调整后的分析中,滥用阿片类药物的人明显更有可能是男性,有更多的酒精和其他物质使用,并报告暴力,自我效能感和社会支持较低。健康的社会决定因素、其他物质使用、社会支持、自我效能等是区分滥用阿片类药物的asa与未来有滥用风险的asa的关键因素。针对这些风险/保护因素,可以改进预防和早期干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Understanding risk and protective factors associated with opioid misuse among at-risk adolescents and young adults in the emergency department

Background

Opioid misuse/opioid use disorder prevention strategies tailored for risk and protective factors are needed among adolescents and young adults (AYAs). We describe baseline risk/protective factors related to opioid misuse among at-risk AYAs who attended Emergency Departments (EDs) enrolled in a randomized controlled trial.

Methods

People who recently visited an ED (ages 16–30) and self-reported 1) past-year prescription opioid use+a risk factor for misuse (i.e., drug use, binge drinking, depression symptoms, suicide risk) or 2) heroin or prescription opioid misuse at screening were enrolled. Measures assessed background characteristics and risk/protective factors. Analyses compared participants based on whether they reported opioid misuse or were at-risk for misuse.

Results

We enrolled 1155 people (27.5 % male); 79.5 % reported opioid use+risk factor and 20.5 % reported opioid misuse. In unadjusted analyses, relative to those with opioid use+risk factor, those with opioid misuse were significantly more likely to report: male sex, Black/African American race, receiving public assistance, food insecurity, stronger opioid use motives, greater substance use, a prior suicide attempt, violence involvement, and greater impulsivity. They also reported lower social support, prosocial activities, and self-efficacy to avoid substances. In adjusted analyses, those with opioid misuse were significantly more likely to be male, have greater alcohol and other substance use, and report violence, with lower self-efficacy and social support.

Discussion

Social determinants of health, other substance use, social support, self-efficacy, etc., were key factors differentiating AYAs who have misused opioids from those at-risk for future misuse. Prevention and early interventions may be improved via tailoring for these risk/protective factors.
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来源期刊
Drug and alcohol dependence
Drug and alcohol dependence 医学-精神病学
CiteScore
7.40
自引率
7.10%
发文量
409
审稿时长
41 days
期刊介绍: Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.
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