FDG PET -TDM对儿科骨髓瘤管理的贡献

IF 0.2 4区医学 Q4 PATHOLOGY

Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2025-08-01 DOI:10.1016/j.mednuc.2025.06.005

V. Isnardi , N. Jehanno , T. Cassou-Mounat , B. Jonca , P. Marec Berard

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引用次数: 0

摘要

骨肉瘤，包括骨肉瘤（OS）和尤文氏肉瘤（ES），是一种罕见但侵袭性的肿瘤，需要专门的治疗。在现有的成像技术中，FDG PET- ct （PET FDG）近年来在这一肿瘤学领域发挥了重要作用。由于其检测肺外转移的高灵敏度，特别是检测骨和骨髓的累及，它已被确定为初始分期。PET FDG也被用于评估晚期转移性疾病患者对新辅助化疗和全身治疗的治疗反应。与全身MRI相比，PET FDG提供了更好的可用性和更少的获取限制，这对管理儿科人群很重要。此外，最新的技术进步将改善这些年轻患者的辐射防护。

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Apport de la TEP-TDM FDG dans la prise en charge des sarcomes osseux en pédiatrie

Bone sarcomas, including osteosarcomas (OS) and Ewing sarcomas (ES), are rare but aggressive tumors requiring specialized care. Among the available imaging techniques, FDG PET-CT (PET FDG) has taken a significant role in this oncological field in recent years. It has been established for the initial staging due to its high sensitivity for detecting extrapulmonary metastases, particularly for detecting bone and bone marrow involvement. The use of PET FDG is also developing for the evaluation of therapeutic response to neoadjuvant chemotherapy and systemic treatments in patients with advanced metastatic disease. PET FDG offers better availability and fewer acquisition constraints compared to whole-body MRI, which is important for managing a pediatric population. Furthermore, the latest technological advances will improve radiation protection for these young patients.

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来源期刊

Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique PATHOLOGY-

CiteScore

0.30

自引率

0.00%

发文量

160

审稿时长

19.8 weeks

期刊介绍： Le but de Médecine nucléaire - Imagerie fonctionnelle et métabolique est de fournir une plate-forme d''échange d''informations cliniques et scientifiques pour la communauté francophone de médecine nucléaire, et de constituer une expérience pédagogique de la rédaction médicale en conformité avec les normes internationales.