利用量子光提高受激拉曼散射显微镜的灵敏度：现状与未来挑战

IF 3.6 2区物理与天体物理 Q2 PHYSICS, APPLIED

Applied Physics Letters Pub Date : 2025-07-29 DOI:10.1063/5.0273335

Zicong Xu, Sho Nitanai, Kenichi Oguchi, Yasuyuki Ozeki

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引用次数: 0

摘要

量子增强受激拉曼散射（qesrs）显微镜是生物医学成像、激光显微镜和量子光学的交汇点，旨在实现敏感的分子振动成像。本展望探讨了这一新兴领域的现状，整合了这些不同学科的观点，以突出其推进生物和医学成像的潜力。我们讨论了利用量子光推动SRS显微镜灵敏度极限的关键挑战和未来方向，为下一代成像模式铺平了道路。

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Pushing the sensitivity of stimulated Raman scattering microscopy with quantum light: Current status and future challenges

Quantum-enhanced stimulated Raman scattering (QE-SRS) microscopy sits at the intersection of biomedical imaging, laser microscopy, and quantum optics toward realizing sensitive molecular-vibrational imaging. This Perspective explores the current status of this emerging field, integrating viewpoints from these diverse disciplines to highlight its potential for advancing biological and medical imaging. We discuss key challenges and future directions in leveraging quantum light to push the sensitivity limits of SRS microscopy, paving the way for next-generation imaging modalities.

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来源期刊

Applied Physics Letters 物理-物理：应用

CiteScore

6.40

自引率

10.00%

发文量

1821

审稿时长

1.6 months

期刊介绍： Applied Physics Letters (APL) features concise, up-to-date reports on significant new findings in applied physics. Emphasizing rapid dissemination of key data and new physical insights, APL offers prompt publication of new experimental and theoretical papers reporting applications of physics phenomena to all branches of science, engineering, and modern technology. In addition to regular articles, the journal also publishes invited Fast Track, Perspectives, and in-depth Editorials which report on cutting-edge areas in applied physics. APL Perspectives are forward-looking invited letters which highlight recent developments or discoveries. Emphasis is placed on very recent developments, potentially disruptive technologies, open questions and possible solutions. They also include a mini-roadmap detailing where the community should direct efforts in order for the phenomena to be viable for application and the challenges associated with meeting that performance threshold. Perspectives are characterized by personal viewpoints and opinions of recognized experts in the field. Fast Track articles are invited original research articles that report results that are particularly novel and important or provide a significant advancement in an emerging field. Because of the urgency and scientific importance of the work, the peer review process is accelerated. If, during the review process, it becomes apparent that the paper does not meet the Fast Track criterion, it is returned to a normal track.