Muhammed A. M. Hammad, Elia Abou Chawareb, Jeffrey Lee, Mohammed Mahdi, Maryam Ahmadi, Giovanna Giannico, Faysal A. Yafi
{"title":"阴茎血管内乳头状内皮增生(马松瘤)一例。","authors":"Muhammed A. M. Hammad, Elia Abou Chawareb, Jeffrey Lee, Mohammed Mahdi, Maryam Ahmadi, Giovanna Giannico, Faysal A. Yafi","doi":"10.1038/s41443-025-01136-0","DOIUrl":null,"url":null,"abstract":"Intravascular papillary endothelial hyperplasia (IPEH), or Masson’s tumor, is an uncommon, benign vascular lesion that can mimic malignant neoplasms. Although commonly found in the skin and soft tissues, its occurrence in the penis is extremely rare. We report the case of a 51-year-old male who presented with a painless, progressively enlarging penile mass. Imaging suggested a benign etiology, and the patient underwent surgical excision. Histopathological analysis confirmed the diagnosis of Masson’s tumor, revealing papillary endothelial proliferation within a thrombotic background. The postoperative course was uneventful, with satisfactory wound healing and no recurrence at follow-up. While rare, penile Masson’s tumor should be considered in the differential diagnosis of vascular penile lesions to avoid misdiagnosis and overtreatment. Surgical excision remains the definitive treatment, with excellent prognosis.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"37 9","pages":"794-796"},"PeriodicalIF":2.5000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A rare case of intravascular papillary endothelial hyperplasia (Masson’s tumor) of the penis\",\"authors\":\"Muhammed A. M. Hammad, Elia Abou Chawareb, Jeffrey Lee, Mohammed Mahdi, Maryam Ahmadi, Giovanna Giannico, Faysal A. Yafi\",\"doi\":\"10.1038/s41443-025-01136-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Intravascular papillary endothelial hyperplasia (IPEH), or Masson’s tumor, is an uncommon, benign vascular lesion that can mimic malignant neoplasms. Although commonly found in the skin and soft tissues, its occurrence in the penis is extremely rare. We report the case of a 51-year-old male who presented with a painless, progressively enlarging penile mass. Imaging suggested a benign etiology, and the patient underwent surgical excision. Histopathological analysis confirmed the diagnosis of Masson’s tumor, revealing papillary endothelial proliferation within a thrombotic background. The postoperative course was uneventful, with satisfactory wound healing and no recurrence at follow-up. While rare, penile Masson’s tumor should be considered in the differential diagnosis of vascular penile lesions to avoid misdiagnosis and overtreatment. Surgical excision remains the definitive treatment, with excellent prognosis.\",\"PeriodicalId\":14068,\"journal\":{\"name\":\"International Journal of Impotence Research\",\"volume\":\"37 9\",\"pages\":\"794-796\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Impotence Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.nature.com/articles/s41443-025-01136-0\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Impotence Research","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s41443-025-01136-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
A rare case of intravascular papillary endothelial hyperplasia (Masson’s tumor) of the penis
Intravascular papillary endothelial hyperplasia (IPEH), or Masson’s tumor, is an uncommon, benign vascular lesion that can mimic malignant neoplasms. Although commonly found in the skin and soft tissues, its occurrence in the penis is extremely rare. We report the case of a 51-year-old male who presented with a painless, progressively enlarging penile mass. Imaging suggested a benign etiology, and the patient underwent surgical excision. Histopathological analysis confirmed the diagnosis of Masson’s tumor, revealing papillary endothelial proliferation within a thrombotic background. The postoperative course was uneventful, with satisfactory wound healing and no recurrence at follow-up. While rare, penile Masson’s tumor should be considered in the differential diagnosis of vascular penile lesions to avoid misdiagnosis and overtreatment. Surgical excision remains the definitive treatment, with excellent prognosis.
期刊介绍:
International Journal of Impotence Research: The Journal of Sexual Medicine addresses sexual medicine for both genders as an interdisciplinary field. This includes basic science researchers, urologists, endocrinologists, cardiologists, family practitioners, gynecologists, internists, neurologists, psychiatrists, psychologists, radiologists and other health care clinicians.