应对急诊科脆弱老年人的营养风险和脱水:一项关于检测、治疗和随访的单组可行性研究

IF 2.6 Q3 NUTRITION & DIETETICS
Clinical nutrition ESPEN Pub Date : 2025-10-01 Epub Date: 2025-07-30 DOI:10.1016/j.clnesp.2025.07.1125
Martine Kjærsgaard Nielsen, Emma Dalbæk Mejlvang Pedersen, Anne Wilkens Knudsen, Tina Munk, Anne Marie Beck
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引用次数: 0

摘要

背景和目的:脱水和营养不良在急诊科(ED)的老年人中非常普遍。到目前为止,还没有证据表明在ED环境中直接启动有针对性的营养和水合作用干预。本研究的主要目的是评估这种干预措施的可行性,从资格、招募率、保留率、代表性、干预措施的依从性和效果以及结局数据收集的完整性等方面进行定义。这一信息将有助于建立设计最终未来确定的随机对照试验(RCT)所需的参数。方法:本研究是一项可行性研究,在ED进行,并与四个市合作。有营养风险的老年患者(根据2002年全国人口调查,营养风险评分至少为3分)和/或脱水(p-渗透压>295毫摩尔/升)在急诊科接受了个人饮食咨询,并由市政当局的营养师或其他保健专业人员进行了随访。收集了关于老年参与者的资格、招募和保留以及数据收集的完整性的数据。依从性评估为能量、蛋白质和液体摄入的变化、自我效能、生活质量、再入院率和30天内的死亡率。结果:在326名研究筛选者中,314名(96%)由于脱水或营养风险而符合条件。有可能招募超过一半(58%)的受邀参与者,保留率很高(90%)。大多数被评估者的数据收集完整性在80%以上。能量(p=0.0012)、蛋白质(p=0.0002)和液体(p=0.0040)、生活质量(p=0.0007)和自我效能(p=0.0498)的摄入量均有所增加。再入院率为19%,死亡率为7%。结论:在急诊科对易受伤害的老年患者进行营养风险和脱水的检测、治疗和随访,在适格性、招募性和保留性方面是可行的。此外,大多数选择的结果具有较高的完整性,因此可能是最终未来RCT中包含的相关参数。该研究的探索性限制了确定的结论;然而,积极的研究结果支持开展一项明确的随机对照试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Addressing nutritional risk and dehydration in vulnerable older adults in the emergency department: A single-arm feasibility study on detection, treatment, and follow-up.

Background and aim: Dehydration and malnutrition are highly prevalent among older adults in the emergency department (ED). To date, there is no evidence regarding targeted nutrition and hydration interventions initiated directly in the ED setting. The primary aim of the study was to assess the feasibility of such an intervention, defined in terms of eligibility, recruitment rate, retention, representativeness, compliance to and effect of the intervention, and completeness of outcome data collection. This information will help establish the parameters required to design an eventual future definitive randomized controlled trial (RCT).

Methods: The study was a feasibility study conducted at the ED and in cooperation with four municipalities. Older patients at nutritional risk (defined by a nutritional risk score of minimum 3 according to NRS 2002) and/or dehydrated (p-osmolarity >295 mmol/L) were provided with individual dietary counselling initiated in the emergency department and followed-up by a dietitian or other health care professionals in the municipalities. Data were collected on eligibility, recruitment, and retention of the older participants and completeness of data collection. Compliance was assessed as change in intake of energy, protein and fluids, self-efficacy, quality of life, prevalence of readmissions, and mortality within 30 days.

Results: Of those 326 screened for the study, 314 (96%) were eligible due to either dehydration or nutritional risk. It was possible to recruit more than half (58%) of those invited to participate and the retention rate was high (90%). Completeness of data collection was above 80% for most of those assessed. There was an increase in intake of energy (p = 0.0012), protein (p = 0.0002), and fluid (p = 0.0040), quality of life (p = 0.0007), and self-efficacy (p = 0.0498). The prevalence of readmissions was 19%, and 7% had died.

Conclusion: The detection, treatment and follow-up of nutritional risk and dehydration in vulnerable older patients in the ED was proven to be feasible in relation to eligibility, recruitment, and retention. Further, most of the chosen outcomes had a high rate of completeness and hence may be relevant parameters to include in an eventual future RCT. The explorative nature of the study limits firm conclusions; however, the positive findings support the initiation of a definitive RCT.

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来源期刊
Clinical nutrition ESPEN
Clinical nutrition ESPEN NUTRITION & DIETETICS-
CiteScore
4.90
自引率
3.30%
发文量
512
期刊介绍: Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.
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