{"title":"休克指标在急诊科钝性创伤患者中的预测作用。","authors":"Ozan Utku Deveci, Ataman Köse, Çağrı Safa Buyurgan, Akif Yarkaç, Seyran Bozkurt, Cumhur Özcan, Didem Derici Yıldırım","doi":"10.1080/17520363.2025.2542109","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the effectiveness of Shock Index (SI), Modified Shock Index (MSI), and Age Shock Index (Age SI) in predicting blood transfusion need, surgical intervention, hospital outcomes, and injury severity in blunt trauma patients.</p><p><strong>Methods: </strong>This retrospective study included 267 adult patients admitted with blunt trauma to the emergency department of a tertiary university hospital between 1 December 2018, and 1 December 2019. Patients with isolated hand/foot trauma, isolated traumatic brain injury, isolated spinal injuries, or minor trauma (AIS ≤2) were excluded. SI, MSI, and Age SI were calculated and analyzed.</p><p><strong>Results: </strong>SI (<i>p</i> < 0.001), Age SI (<i>p</i> = 0.001), and MSI (<i>p</i> < 0.001) were significantly associated with blood transfusion and mortality. SI > 0.933 and MSI > 1.159 showed good predictive accuracy for blood transfusion; Age SI > 30.945 showed moderate accuracy. For mortality, SI > 1.015, MSI > 1.333, and Age SI > 67.065 demonstrated good predictive power (all <i>p</i> < 0.001). SI and MSI correlated moderately with injury severity (<i>p</i> < 0.001), with SI > 0.905 and MSI > 1.181 indicating significant predictive value.</p><p><strong>Conclusion: </strong>SI, MSI, and Age SI can predict early blood transfusion and mortality in blunt trauma patients. SI and MSI appear more reliable than Age SI, particularly in predicting transfusion need and injury severity.</p>","PeriodicalId":9182,"journal":{"name":"Biomarkers in medicine","volume":" ","pages":"747-755"},"PeriodicalIF":2.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416162/pdf/","citationCount":"0","resultStr":"{\"title\":\"Shock indices as predictors in blunt trauma patients in the emergency department.\",\"authors\":\"Ozan Utku Deveci, Ataman Köse, Çağrı Safa Buyurgan, Akif Yarkaç, Seyran Bozkurt, Cumhur Özcan, Didem Derici Yıldırım\",\"doi\":\"10.1080/17520363.2025.2542109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>To evaluate the effectiveness of Shock Index (SI), Modified Shock Index (MSI), and Age Shock Index (Age SI) in predicting blood transfusion need, surgical intervention, hospital outcomes, and injury severity in blunt trauma patients.</p><p><strong>Methods: </strong>This retrospective study included 267 adult patients admitted with blunt trauma to the emergency department of a tertiary university hospital between 1 December 2018, and 1 December 2019. Patients with isolated hand/foot trauma, isolated traumatic brain injury, isolated spinal injuries, or minor trauma (AIS ≤2) were excluded. SI, MSI, and Age SI were calculated and analyzed.</p><p><strong>Results: </strong>SI (<i>p</i> < 0.001), Age SI (<i>p</i> = 0.001), and MSI (<i>p</i> < 0.001) were significantly associated with blood transfusion and mortality. SI > 0.933 and MSI > 1.159 showed good predictive accuracy for blood transfusion; Age SI > 30.945 showed moderate accuracy. For mortality, SI > 1.015, MSI > 1.333, and Age SI > 67.065 demonstrated good predictive power (all <i>p</i> < 0.001). SI and MSI correlated moderately with injury severity (<i>p</i> < 0.001), with SI > 0.905 and MSI > 1.181 indicating significant predictive value.</p><p><strong>Conclusion: </strong>SI, MSI, and Age SI can predict early blood transfusion and mortality in blunt trauma patients. SI and MSI appear more reliable than Age SI, particularly in predicting transfusion need and injury severity.</p>\",\"PeriodicalId\":9182,\"journal\":{\"name\":\"Biomarkers in medicine\",\"volume\":\" \",\"pages\":\"747-755\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416162/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomarkers in medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/17520363.2025.2542109\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomarkers in medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/17520363.2025.2542109","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Shock indices as predictors in blunt trauma patients in the emergency department.
Aims: To evaluate the effectiveness of Shock Index (SI), Modified Shock Index (MSI), and Age Shock Index (Age SI) in predicting blood transfusion need, surgical intervention, hospital outcomes, and injury severity in blunt trauma patients.
Methods: This retrospective study included 267 adult patients admitted with blunt trauma to the emergency department of a tertiary university hospital between 1 December 2018, and 1 December 2019. Patients with isolated hand/foot trauma, isolated traumatic brain injury, isolated spinal injuries, or minor trauma (AIS ≤2) were excluded. SI, MSI, and Age SI were calculated and analyzed.
Results: SI (p < 0.001), Age SI (p = 0.001), and MSI (p < 0.001) were significantly associated with blood transfusion and mortality. SI > 0.933 and MSI > 1.159 showed good predictive accuracy for blood transfusion; Age SI > 30.945 showed moderate accuracy. For mortality, SI > 1.015, MSI > 1.333, and Age SI > 67.065 demonstrated good predictive power (all p < 0.001). SI and MSI correlated moderately with injury severity (p < 0.001), with SI > 0.905 and MSI > 1.181 indicating significant predictive value.
Conclusion: SI, MSI, and Age SI can predict early blood transfusion and mortality in blunt trauma patients. SI and MSI appear more reliable than Age SI, particularly in predicting transfusion need and injury severity.
期刊介绍：
Biomarkers are physical, functional or biochemical indicators of physiological or disease processes. These key indicators can provide vital information in determining disease prognosis, in predicting of response to therapies, adverse events and drug interactions, and in establishing baseline risk. The explosion of interest in biomarker research is driving the development of new predictive, diagnostic and prognostic products in modern medical practice, and biomarkers are also playing an increasingly important role in the discovery and development of new drugs. For the full utility of biomarkers to be realized, we require greater understanding of disease mechanisms, and the interplay between disease mechanisms, therapeutic interventions and the proposed biomarkers. However, in attempting to evaluate the pros and cons of biomarkers systematically, we are moving into new, challenging territory.
Biomarkers in Medicine (ISSN 1752-0363) is a peer-reviewed, rapid publication journal delivering commentary and analysis on the advances in our understanding of biomarkers and their potential and actual applications in medicine. The journal facilitates translation of our research knowledge into the clinic to increase the effectiveness of medical practice.
As the scientific rationale and regulatory acceptance for biomarkers in medicine and in drug development become more fully established, Biomarkers in Medicine provides the platform for all players in this increasingly vital area to communicate and debate all issues relating to the potential utility and applications.
Each issue includes a diversity of content to provide rounded coverage for the research professional. Articles include Guest Editorials, Interviews, Reviews, Research Articles, Perspectives, Priority Paper Evaluations, Special Reports, Case Reports, Conference Reports and Company Profiles. Review coverage is divided into themed sections according to area of therapeutic utility with some issues including themed sections on an area of topical interest.
Biomarkers in Medicine provides a platform for commentary and debate for all professionals with an interest in the identification of biomarkers, elucidation of their role and formalization and approval of their application in modern medicine. The audience for Biomarkers in Medicine includes academic and industrial researchers, clinicians, pathologists, clinical chemists and regulatory professionals.
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