{"title":"单肺移植受者持续性漏气和内镜下肺体积缩小的支气管内瓣膜治疗：1例报告和文献复习。","authors":"Joscha Godts, Isabelle Etienne, Christiane Knoop, Dimitri Leduc, Youri Sokolow, Maarten Vander Kuylen, Olivier Taton","doi":"10.1002/rcr2.70305","DOIUrl":null,"url":null,"abstract":"<p><p>The use of endobronchial valves (EBV) is a recommended treatment for persistent air leak (PAL) and endoscopic lung volume reduction (ELVR) in selected patients with severe emphysema and absence of collateral ventilation. We report the case of a 52-year-old man who was scheduled for a bilateral sequential lung transplantation, converted to a left single lung transplantation (SLTx) after failure to remove the right lung due to prior thoracic surgery. The post-operative course was complicated by a PAL on the right non-transplanted side, unresponsive to prolonged drainage. Placement of EBV in the right upper and middle lobes, following collateral ventilation evaluation with the Chartis system, resulted in the resolution of the air leak and a concomitant lung volume reduction. Based on a literature review regarding ELVR in single-lung transplanted recipients, we suggest that ELVR with EBV could be a therapeutic option with an acceptable safety profile in this unique population.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 8","pages":"e70305"},"PeriodicalIF":0.8000,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310813/pdf/","citationCount":"0","resultStr":"{\"title\":\"Endobronchial Valve Treatment for Persistent Air Leak and Endoscopic Lung Volume Reduction of Native Lung in a Single Lung Transplant Recipient: A Case Report and Literature Review.\",\"authors\":\"Joscha Godts, Isabelle Etienne, Christiane Knoop, Dimitri Leduc, Youri Sokolow, Maarten Vander Kuylen, Olivier Taton\",\"doi\":\"10.1002/rcr2.70305\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The use of endobronchial valves (EBV) is a recommended treatment for persistent air leak (PAL) and endoscopic lung volume reduction (ELVR) in selected patients with severe emphysema and absence of collateral ventilation. We report the case of a 52-year-old man who was scheduled for a bilateral sequential lung transplantation, converted to a left single lung transplantation (SLTx) after failure to remove the right lung due to prior thoracic surgery. The post-operative course was complicated by a PAL on the right non-transplanted side, unresponsive to prolonged drainage. Placement of EBV in the right upper and middle lobes, following collateral ventilation evaluation with the Chartis system, resulted in the resolution of the air leak and a concomitant lung volume reduction. Based on a literature review regarding ELVR in single-lung transplanted recipients, we suggest that ELVR with EBV could be a therapeutic option with an acceptable safety profile in this unique population.</p>\",\"PeriodicalId\":45846,\"journal\":{\"name\":\"Respirology Case Reports\",\"volume\":\"13 8\",\"pages\":\"e70305\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310813/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Respirology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/rcr2.70305\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respirology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/rcr2.70305","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Endobronchial Valve Treatment for Persistent Air Leak and Endoscopic Lung Volume Reduction of Native Lung in a Single Lung Transplant Recipient: A Case Report and Literature Review.
The use of endobronchial valves (EBV) is a recommended treatment for persistent air leak (PAL) and endoscopic lung volume reduction (ELVR) in selected patients with severe emphysema and absence of collateral ventilation. We report the case of a 52-year-old man who was scheduled for a bilateral sequential lung transplantation, converted to a left single lung transplantation (SLTx) after failure to remove the right lung due to prior thoracic surgery. The post-operative course was complicated by a PAL on the right non-transplanted side, unresponsive to prolonged drainage. Placement of EBV in the right upper and middle lobes, following collateral ventilation evaluation with the Chartis system, resulted in the resolution of the air leak and a concomitant lung volume reduction. Based on a literature review regarding ELVR in single-lung transplanted recipients, we suggest that ELVR with EBV could be a therapeutic option with an acceptable safety profile in this unique population.
期刊介绍：
Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
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