揭示诊断之谜:18F-FDG PET和骨扫描阴性小叶乳腺癌骨转移1例报告。

IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Sharjeel Usmani, Khulood Al Riyami, Anjali Jain, Asiya Al Busaidi, Paul Dumasig, Vipin V Jayakrishnan, Subhash Kheruka, Najeeb Ahmed
{"title":"揭示诊断之谜:18F-FDG PET和骨扫描阴性小叶乳腺癌骨转移1例报告。","authors":"Sharjeel Usmani, Khulood Al Riyami, Anjali Jain, Asiya Al Busaidi, Paul Dumasig, Vipin V Jayakrishnan, Subhash Kheruka, Najeeb Ahmed","doi":"10.4274/mirt.galenos.2025.75875","DOIUrl":null,"url":null,"abstract":"<p><p>Identifying osseous metastases by imaging is essential and may be challenging in patients with lobular breast cancer. We present a case of a 66-year-old woman with lobular breast cancer who underwent <sup>18</sup>F- fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) for staging purposes. <sup>18</sup>F-FDG PET/CT reveals minimal FDG uptake in the primary tumor cells. Prominent sclerotic lesions with low FDG avidity are seen in the spinal and pelvic bones. The subsequent Tc-99m methylene diphosphonate bone scan is unremarkable. The magnetic resonance multiple imaging (MRI) reveals bone metastases. MRI may be beneficial in invasive lobular carcinoma. MRI facilitates improved metastatic evaluation, especially in bone-only and bone-predominant metastatic malignancies, when assessment with <sup>18</sup>F-FDG PET/CT may be difficult and constrained.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Unveiling the Diagnostic Mystery: <sup>18</sup>F-FDG PET and Bone Scan Negative in Bone Metastases of Lobular Breast Cancer: A Case Report.\",\"authors\":\"Sharjeel Usmani, Khulood Al Riyami, Anjali Jain, Asiya Al Busaidi, Paul Dumasig, Vipin V Jayakrishnan, Subhash Kheruka, Najeeb Ahmed\",\"doi\":\"10.4274/mirt.galenos.2025.75875\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Identifying osseous metastases by imaging is essential and may be challenging in patients with lobular breast cancer. We present a case of a 66-year-old woman with lobular breast cancer who underwent <sup>18</sup>F- fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) for staging purposes. <sup>18</sup>F-FDG PET/CT reveals minimal FDG uptake in the primary tumor cells. Prominent sclerotic lesions with low FDG avidity are seen in the spinal and pelvic bones. The subsequent Tc-99m methylene diphosphonate bone scan is unremarkable. The magnetic resonance multiple imaging (MRI) reveals bone metastases. MRI may be beneficial in invasive lobular carcinoma. MRI facilitates improved metastatic evaluation, especially in bone-only and bone-predominant metastatic malignancies, when assessment with <sup>18</sup>F-FDG PET/CT may be difficult and constrained.</p>\",\"PeriodicalId\":44681,\"journal\":{\"name\":\"Molecular Imaging and Radionuclide Therapy\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Imaging and Radionuclide Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4274/mirt.galenos.2025.75875\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Imaging and Radionuclide Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4274/mirt.galenos.2025.75875","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

摘要

通过影像学识别骨转移是必要的,对小叶乳腺癌患者可能具有挑战性。我们报告了一位66岁的小叶性乳腺癌患者,她接受了18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG PET/CT)进行分期。18F-FDG PET/CT显示原发肿瘤细胞中FDG摄取极少。脊柱和骨盆骨可见明显的硬化性病变,FDG密度低。随后的Tc-99m二膦酸亚甲基骨扫描结果并不显著。磁共振多重成像(MRI)显示骨转移。MRI对浸润性小叶癌可能是有益的。当18F-FDG PET/CT评估可能困难且受限时,MRI有助于改善转移性评估,特别是在仅骨和骨为主的转移性恶性肿瘤中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unveiling the Diagnostic Mystery: 18F-FDG PET and Bone Scan Negative in Bone Metastases of Lobular Breast Cancer: A Case Report.

Identifying osseous metastases by imaging is essential and may be challenging in patients with lobular breast cancer. We present a case of a 66-year-old woman with lobular breast cancer who underwent 18F- fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) for staging purposes. 18F-FDG PET/CT reveals minimal FDG uptake in the primary tumor cells. Prominent sclerotic lesions with low FDG avidity are seen in the spinal and pelvic bones. The subsequent Tc-99m methylene diphosphonate bone scan is unremarkable. The magnetic resonance multiple imaging (MRI) reveals bone metastases. MRI may be beneficial in invasive lobular carcinoma. MRI facilitates improved metastatic evaluation, especially in bone-only and bone-predominant metastatic malignancies, when assessment with 18F-FDG PET/CT may be difficult and constrained.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Molecular Imaging and Radionuclide Therapy
Molecular Imaging and Radionuclide Therapy RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Molecular Imaging and Radionuclide Therapy (Mol Imaging Radionucl Ther, MIRT) is publishes original research articles, invited reviews, editorials, short communications, letters, consensus statements, guidelines and case reports with a literature review on the topic, in the field of molecular imaging, multimodality imaging, nuclear medicine, radionuclide therapy, radiopharmacy, medical physics, dosimetry and radiobiology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信