18F-PSMA1007 PET显示类似淋巴结的主动脉钙化。

IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Salah Nabih Oueriagli, Omar Ait Sahel, Ikram Zahfir, Meryem Aboussabr, Yassir Benameur, Abderrahim Doudouh
{"title":"18F-PSMA1007 PET显示类似淋巴结的主动脉钙化。","authors":"Salah Nabih Oueriagli, Omar Ait Sahel, Ikram Zahfir, Meryem Aboussabr, Yassir Benameur, Abderrahim Doudouh","doi":"10.4274/mirt.galenos.2025.78736","DOIUrl":null,"url":null,"abstract":"<p><p>An 82-year-old patient with high-risk prostate adenocarcinoma, previously treated with radiotherapy and hormone therapy, presented with biochemical recurrence, as evidenced by a prostate-specific antigen level of 10 ng/mL. A positron emission tomography/computed tomography (PET/CT) scan using <sup>18</sup>F-prostate-specific membrane antigen (PSMA ) 1007 revealed significant uptake at the prostate apex and multiple hypermetabolic osseous lesions in the sternum and L3, suggestive of local recurrence and metastasis. However, several hypermetabolic foci in the abdominopelvic region raised suspicion for potential involvement of the lumbar-aortic lymph nodes due to their moderate to intense uptake. After further investigation, these findings were attributed to active aortic calcifications. This case highlights a rare cause of false-positive results in <sup>18</sup>F-PSMA 1007 PET/CT imaging and underscores the need for additional evaluations, such as abdominopelvic magnetic resonance imaging and renal and phosphocalcic assessments, when such results are suspected.</p>","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Aortic Calcifications Mimicking Lymph Nodes on <sup>18</sup>F-PSMA1007 PET.\",\"authors\":\"Salah Nabih Oueriagli, Omar Ait Sahel, Ikram Zahfir, Meryem Aboussabr, Yassir Benameur, Abderrahim Doudouh\",\"doi\":\"10.4274/mirt.galenos.2025.78736\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>An 82-year-old patient with high-risk prostate adenocarcinoma, previously treated with radiotherapy and hormone therapy, presented with biochemical recurrence, as evidenced by a prostate-specific antigen level of 10 ng/mL. A positron emission tomography/computed tomography (PET/CT) scan using <sup>18</sup>F-prostate-specific membrane antigen (PSMA ) 1007 revealed significant uptake at the prostate apex and multiple hypermetabolic osseous lesions in the sternum and L3, suggestive of local recurrence and metastasis. However, several hypermetabolic foci in the abdominopelvic region raised suspicion for potential involvement of the lumbar-aortic lymph nodes due to their moderate to intense uptake. After further investigation, these findings were attributed to active aortic calcifications. This case highlights a rare cause of false-positive results in <sup>18</sup>F-PSMA 1007 PET/CT imaging and underscores the need for additional evaluations, such as abdominopelvic magnetic resonance imaging and renal and phosphocalcic assessments, when such results are suspected.</p>\",\"PeriodicalId\":44681,\"journal\":{\"name\":\"Molecular Imaging and Radionuclide Therapy\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Imaging and Radionuclide Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4274/mirt.galenos.2025.78736\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Imaging and Radionuclide Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4274/mirt.galenos.2025.78736","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

摘要

一例82岁高危前列腺腺癌患者,既往接受放疗和激素治疗,前列腺特异性抗原水平为10 ng/mL,生化复发。正电子发射断层扫描/计算机断层扫描(PET/CT)使用18f -前列腺特异性膜抗原(PSMA) 1007扫描显示前列腺尖明显摄取,胸骨和L3多发高代谢骨性病变,提示局部复发和转移。然而,在腹部骨盆区域的几个高代谢灶由于其中度至强烈的摄取,引起了腰主动脉淋巴结潜在受累的怀疑。进一步调查后,这些发现归因于活跃的主动脉钙化。该病例强调了18F-PSMA 1007 PET/CT成像假阳性结果的罕见原因,并强调了当怀疑此类结果时需要进行额外的评估,如腹部骨盆磁共振成像和肾脏和磷钙评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aortic Calcifications Mimicking Lymph Nodes on 18F-PSMA1007 PET.

An 82-year-old patient with high-risk prostate adenocarcinoma, previously treated with radiotherapy and hormone therapy, presented with biochemical recurrence, as evidenced by a prostate-specific antigen level of 10 ng/mL. A positron emission tomography/computed tomography (PET/CT) scan using 18F-prostate-specific membrane antigen (PSMA ) 1007 revealed significant uptake at the prostate apex and multiple hypermetabolic osseous lesions in the sternum and L3, suggestive of local recurrence and metastasis. However, several hypermetabolic foci in the abdominopelvic region raised suspicion for potential involvement of the lumbar-aortic lymph nodes due to their moderate to intense uptake. After further investigation, these findings were attributed to active aortic calcifications. This case highlights a rare cause of false-positive results in 18F-PSMA 1007 PET/CT imaging and underscores the need for additional evaluations, such as abdominopelvic magnetic resonance imaging and renal and phosphocalcic assessments, when such results are suspected.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Molecular Imaging and Radionuclide Therapy
Molecular Imaging and Radionuclide Therapy RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Molecular Imaging and Radionuclide Therapy (Mol Imaging Radionucl Ther, MIRT) is publishes original research articles, invited reviews, editorials, short communications, letters, consensus statements, guidelines and case reports with a literature review on the topic, in the field of molecular imaging, multimodality imaging, nuclear medicine, radionuclide therapy, radiopharmacy, medical physics, dosimetry and radiobiology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信