[回缩]Twist通过调节TGF - β/Smad3信号通路诱导宫颈癌发生中的上皮-间质转化。

IF 3.9 3区 医学 Q2 ONCOLOGY
Oncology reports Pub Date : 2025-10-01 Epub Date: 2025-08-01 DOI:10.3892/or.2025.8960
Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li-Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao
{"title":"[回缩]Twist通过调节TGF - β/Smad3信号通路诱导宫颈癌发生中的上皮-间质转化。","authors":"Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li-Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao","doi":"10.3892/or.2025.8960","DOIUrl":null,"url":null,"abstract":"<p><p>Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, for the Transwell migration and invasion assay experiments shown in Fig. 3C and D on p. 1791, two pairs of the data panels appeared to be overlapping, suggesting that the same data may have been used in this figure to represent data that were intended to show the results from differently performed experiments. Although the authors responded to the original emailed request from the Editorial Office concerning these data and repeated the experiments shown in this figure, upon performing an independent analysis of the original (published) figures in the office, it came to light that Figs. 1 and 4 also contained probable anomalies. In Fig. 1C and D, there were cells/small areas of the images located in the bottom left hand corners of the images that were strikingly similar, to the extent that this would have been difficult to attribute to coincidence. Furthermore, in the case of Fig. 4, the gel slices in Fig. 4B showed evidence of possible cutting‑and‑splicing events. Owing to the fact that these probable anomalies were also identified that could have affected the interpretation of two additional figures in the published article, the Editor of <i>Oncology Reports</i> has decided that this paper should be retracted from the Journal due to a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 34: 1787‑1794, 2015; DOI: 10.3892/or.2015.4143].</p>","PeriodicalId":19527,"journal":{"name":"Oncology reports","volume":"54 4","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329635/pdf/","citationCount":"0","resultStr":"{\"title\":\"[Retracted] Twist induces epithelial‑mesenchymal transition in cervical carcinogenesis by regulating the TGF‑β/Smad3 signaling pathway.\",\"authors\":\"Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li-Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao\",\"doi\":\"10.3892/or.2025.8960\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, for the Transwell migration and invasion assay experiments shown in Fig. 3C and D on p. 1791, two pairs of the data panels appeared to be overlapping, suggesting that the same data may have been used in this figure to represent data that were intended to show the results from differently performed experiments. Although the authors responded to the original emailed request from the Editorial Office concerning these data and repeated the experiments shown in this figure, upon performing an independent analysis of the original (published) figures in the office, it came to light that Figs. 1 and 4 also contained probable anomalies. In Fig. 1C and D, there were cells/small areas of the images located in the bottom left hand corners of the images that were strikingly similar, to the extent that this would have been difficult to attribute to coincidence. Furthermore, in the case of Fig. 4, the gel slices in Fig. 4B showed evidence of possible cutting‑and‑splicing events. Owing to the fact that these probable anomalies were also identified that could have affected the interpretation of two additional figures in the published article, the Editor of <i>Oncology Reports</i> has decided that this paper should be retracted from the Journal due to a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 34: 1787‑1794, 2015; DOI: 10.3892/or.2015.4143].</p>\",\"PeriodicalId\":19527,\"journal\":{\"name\":\"Oncology reports\",\"volume\":\"54 4\",\"pages\":\"\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329635/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oncology reports\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3892/or.2025.8960\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/1 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oncology reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3892/or.2025.8960","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

在这篇论文发表之后,一位关心的读者提请编辑注意,对于图3C和D所示的Transwell迁移和入侵分析实验,两对数据面板似乎是重叠的,这表明在这个图中可能使用了相同的数据来表示旨在显示不同实验结果的数据。虽然作者回复了编辑部关于这些数据的原始电子邮件请求,并重复了图中所示的实验,但在编辑部对原始(已发表)数据进行独立分析后,发现图1和图4也可能存在异常。在图1C和D中,位于图像左下角的图像的细胞/小区域惊人地相似,以至于很难将其归因于巧合。此外,在图4的情况下,图4B中的凝胶切片显示了可能的切割和剪接事件的证据。由于这些可能的异常也被确定,可能会影响对已发表文章中另外两个数字的解释,《肿瘤学报告》的编辑决定,由于对所呈现的数据缺乏信心,这篇论文应该从该杂志上撤回。作者被要求对这些问题作出解释,但编辑部没有收到令人满意的答复。对于由此给读者带来的不便,本刊编辑深表歉意。肿瘤报告34:1787‑1794,2015;DOI: 10.3892 / or.2015.4143]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Retracted] Twist induces epithelial‑mesenchymal transition in cervical carcinogenesis by regulating the TGF‑β/Smad3 signaling pathway.

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, for the Transwell migration and invasion assay experiments shown in Fig. 3C and D on p. 1791, two pairs of the data panels appeared to be overlapping, suggesting that the same data may have been used in this figure to represent data that were intended to show the results from differently performed experiments. Although the authors responded to the original emailed request from the Editorial Office concerning these data and repeated the experiments shown in this figure, upon performing an independent analysis of the original (published) figures in the office, it came to light that Figs. 1 and 4 also contained probable anomalies. In Fig. 1C and D, there were cells/small areas of the images located in the bottom left hand corners of the images that were strikingly similar, to the extent that this would have been difficult to attribute to coincidence. Furthermore, in the case of Fig. 4, the gel slices in Fig. 4B showed evidence of possible cutting‑and‑splicing events. Owing to the fact that these probable anomalies were also identified that could have affected the interpretation of two additional figures in the published article, the Editor of Oncology Reports has decided that this paper should be retracted from the Journal due to a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 34: 1787‑1794, 2015; DOI: 10.3892/or.2015.4143].

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Oncology reports
Oncology reports 医学-肿瘤学
CiteScore
8.50
自引率
2.40%
发文量
187
审稿时长
3 months
期刊介绍: Oncology Reports is a monthly, peer-reviewed journal devoted to the publication of high quality original studies and reviews concerning a broad and comprehensive view of fundamental and applied research in oncology, focusing on carcinogenesis, metastasis and epidemiology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信